ENSG00000112339

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367820 ENSG00000112339 No_inf pgwt_inf HBS1L protein_coding protein_coding 40.42793 27.07588 44.54185 1.718406 0.6852149 0.7179446 4.075144 2.498684 1.717882 1.748267 1.717882 -0.5379261 0.08823333 0.083650 0.037100 -0.046550 0.99284725 0.02996485 FALSE TRUE
ENST00000367826 ENSG00000112339 No_inf pgwt_inf HBS1L protein_coding protein_coding 40.42793 27.07588 44.54185 1.718406 0.6852149 0.7179446 12.588746 5.622738 16.443276 2.600951 2.208081 1.5464665 0.29669167 0.207625 0.371650 0.164025 0.99284725 0.02996485 FALSE TRUE
ENST00000526100 ENSG00000112339 No_inf pgwt_inf HBS1L protein_coding nonsense_mediated_decay 40.42793 27.07588 44.54185 1.718406 0.6852149 0.7179446 3.577966 0.000000 9.171484 0.000000 3.377467 9.8425835 0.08235000 0.000000 0.209450 0.209450 0.25349151 0.02996485 FALSE TRUE
ENST00000533274 ENSG00000112339 No_inf pgwt_inf HBS1L protein_coding protein_coding 40.42793 27.07588 44.54185 1.718406 0.6852149 0.7179446 5.332750 0.000000 3.949830 0.000000 3.949830 8.6292945 0.10565833 0.000000 0.085275 0.085275 1.00000000 0.02996485 FALSE TRUE
MSTRG.25333.2 ENSG00000112339 No_inf pgwt_inf HBS1L protein_coding   40.42793 27.07588 44.54185 1.718406 0.6852149 0.7179446 4.927786 11.203809 0.778521 2.840408 0.778521 -3.8299834 0.16299167 0.406475 0.017325 -0.389150 0.02996485 0.02996485 FALSE TRUE
MSTRG.25333.3 ENSG00000112339 No_inf pgwt_inf HBS1L protein_coding   40.42793 27.07588 44.54185 1.718406 0.6852149 0.7179446 6.836973 4.609219 9.323637 1.778020 2.286470 1.0147905 0.17924167 0.178750 0.208475 0.029725 0.99323661 0.02996485 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000112339 E001 8.9709776 0.0015149808 0.0001828596 0.004774857 6 134960378 134964628 4251 - 0.812 1.160 1.293
ENSG00000112339 E002 0.1308632 0.0122460406 0.3395246782   6 134964629 134964630 2 - 0.000 0.116 11.639
ENSG00000112339 E003 0.1308632 0.0122460406 0.3395246782   6 134964631 134964632 2 - 0.000 0.116 11.639
ENSG00000112339 E004 16.3970974 0.0008952964 0.0424495109 0.226170151 6 134964633 134964841 209 - 1.168 1.313 0.511
ENSG00000112339 E005 56.2100622 0.0002742348 0.0051270665 0.059310406 6 134964842 134965148 307 - 1.703 1.812 0.371
ENSG00000112339 E006 46.6006437 0.0041366984 0.3164359258 0.642137521 6 134965149 134965290 142 - 1.651 1.701 0.171
ENSG00000112339 E007 42.5871200 0.0003477833 0.6548418111 0.865462362 6 134966329 134966473 145 - 1.643 1.623 -0.068
ENSG00000112339 E008 34.7128940 0.0027280238 0.1669374566 0.473096403 6 134969238 134969338 101 - 1.578 1.503 -0.256
ENSG00000112339 E009 38.0099877 0.0094015834 0.6928395859 0.883182651 6 134978679 134978787 109 - 1.576 1.600 0.083
ENSG00000112339 E010 33.3252275 0.0005369170 0.4964381908 0.777998400 6 134979178 134979268 91 - 1.515 1.551 0.121
ENSG00000112339 E011 0.2287699 0.0154275231 0.4357047041   6 134982293 134982457 165 - 0.144 0.000 -11.560
ENSG00000112339 E012 27.8034423 0.0005288069 0.3107118964 0.637023587 6 134982458 134982562 105 - 1.429 1.486 0.196
ENSG00000112339 E013 1.1122192 0.0109132341 0.3241499538 0.648446488 6 134982563 134983573 1011 - 0.251 0.403 0.963
ENSG00000112339 E014 20.4550927 0.0006754548 0.7630238250 0.915862530 6 134985341 134985409 69 - 1.318 1.338 0.070
ENSG00000112339 E015 26.6128705 0.0005038442 0.4508938745 0.748290103 6 134986066 134986183 118 - 1.454 1.411 -0.149
ENSG00000112339 E016 20.9166677 0.0006688140 0.3449366983 0.666301927 6 134986736 134986810 75 - 1.361 1.300 -0.213
ENSG00000112339 E017 14.9716961 0.0010356123 0.9281763222 0.980032889 6 134987645 134987653 9 - 1.201 1.195 -0.022
ENSG00000112339 E018 35.6922370 0.0004078183 0.7489436767 0.909885810 6 134987654 134987791 138 - 1.553 1.569 0.056
ENSG00000112339 E019 27.2882522 0.0007117338 0.0373041884 0.209914156 6 134993758 134993875 118 - 1.494 1.373 -0.417
ENSG00000112339 E020 15.7888083 0.0010764342 0.0837991851 0.331117831 6 134996777 134996821 45 - 1.271 1.141 -0.459
ENSG00000112339 E021 28.6029800 0.0006620248 0.2238833039 0.548153725 6 134996822 134996942 121 - 1.494 1.426 -0.234
ENSG00000112339 E022 13.5798985 0.0011413115 0.4187469577 0.725083208 6 134997397 134997421 25 - 1.185 1.121 -0.227
ENSG00000112339 E023 38.3382391 0.0003656111 0.5318953178 0.800161386 6 134997422 134997656 235 - 1.602 1.573 -0.101
ENSG00000112339 E024 0.1138060 0.0111972800 0.8600090692   6 135002621 135002733 113 - 0.078 0.000 -10.560
ENSG00000112339 E025 16.9252335 0.0008645635 0.9653355913 0.992380549 6 135002734 135002781 48 - 1.247 1.251 0.013
ENSG00000112339 E026 15.7308133 0.0009578971 0.8332459844 0.943961486 6 135002782 135002814 33 - 1.212 1.228 0.056
ENSG00000112339 E027 16.1834391 0.0008895464 0.9452408895 0.986178359 6 135002815 135002842 28 - 1.232 1.228 -0.016
ENSG00000112339 E028 1.1478696 0.0547236712 0.0261728066 0.170584360 6 135010614 135010731 118 - 0.144 0.497 2.448
ENSG00000112339 E029 0.1141751 0.0111767561 0.8600314325   6 135026854 135026863 10 - 0.078 0.000 -10.560
ENSG00000112339 E030 0.2281253 0.0154077118 0.4357170413   6 135026864 135027066 203 - 0.144 0.000 -11.560
ENSG00000112339 E031 0.0000000       6 135027067 135027196 130 -      
ENSG00000112339 E032 6.3119461 0.0022778310 0.6403080176 0.857689008 6 135035857 135036695 839 - 0.838 0.888 0.193
ENSG00000112339 E033 1.0632624 0.0851605307 0.3239708741 0.648234813 6 135036696 135036794 99 - 0.375 0.207 -1.167
ENSG00000112339 E034 8.2749796 0.0127874490 0.3619632195 0.681415191 6 135036795 135037810 1016 - 1.001 0.905 -0.359
ENSG00000112339 E035 1.1130902 0.1973082016 0.4766893001 0.765562220 6 135037811 135037848 38 - 0.251 0.403 0.963
ENSG00000112339 E036 2.0604448 0.0073741551 0.8629398232 0.956188262 6 135037849 135038026 178 - 0.471 0.497 0.126
ENSG00000112339 E037 0.0000000       6 135038027 135038031 5 -      
ENSG00000112339 E038 29.7445913 0.0006216233 0.0871244084 0.338412698 6 135039573 135039767 195 - 1.521 1.426 -0.325
ENSG00000112339 E039 17.7175086 0.0007814346 0.0924001423 0.348991437 6 135042001 135042126 126 - 1.314 1.195 -0.418
ENSG00000112339 E040 12.7536215 0.0011028197 0.4346374776 0.737018260 6 135050582 135050647 66 - 1.106 1.169 0.226
ENSG00000112339 E041 16.1664379 0.0147022511 0.8450932353 0.948871488 6 135054649 135054884 236 - 1.237 1.220 -0.062
ENSG00000112339 E042 0.0000000       6 135102928 135103056 129 -      

Help

Please Click HERE to learn more details about the results from DEXseq.