ENSG00000112697

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000230461 ENSG00000112697 No_inf pgwt_inf TMEM30A protein_coding protein_coding 179.6687 201.1381 148.641 1.4426 0.9012363 -0.4363291 105.71579 102.70486 101.15792 2.032912 2.297350 -0.0218931 0.59668333 0.510725 0.680800 0.170075 9.073950e-01 6.43381e-09 FALSE TRUE
ENST00000370050 ENSG00000112697 No_inf pgwt_inf TMEM30A protein_coding protein_coding 179.6687 201.1381 148.641 1.4426 0.9012363 -0.4363291 10.20404 0.00000 19.03909 0.000000 2.237303 10.8955064 0.06273333 0.000000 0.128000 0.128000 6.433810e-09 6.43381e-09 FALSE TRUE
ENST00000674151 ENSG00000112697 No_inf pgwt_inf TMEM30A protein_coding protein_coding 179.6687 201.1381 148.641 1.4426 0.9012363 -0.4363291 62.38656 97.45377 26.85057 3.223560 3.646212 -1.8593763 0.33272500 0.484375 0.180525 -0.303850 1.502537e-01 6.43381e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000112697 E001 1.6220896 8.467496e-03 7.727432e-01 9.207633e-01 6 75252924 75252936 13 - 0.385 0.429 0.240
ENSG00000112697 E002 3.1115755 4.510853e-03 8.062784e-01 9.336502e-01 6 75252937 75252947 11 - 0.585 0.619 0.147
ENSG00000112697 E003 2.9969806 4.680631e-03 6.261200e-01 8.502374e-01 6 75252948 75252948 1 - 0.552 0.619 0.299
ENSG00000112697 E004 8.0624870 1.766290e-03 6.866257e-02 2.969709e-01 6 75252949 75252963 15 - 0.826 1.011 0.700
ENSG00000112697 E005 429.3292113 9.842498e-05 6.384944e-81 3.389511e-77 6 75252964 75253612 649 - 2.415 2.718 1.008
ENSG00000112697 E006 1418.7187906 2.739823e-05 1.092614e-13 1.959544e-11 6 75253613 75254598 986 - 3.108 3.162 0.177
ENSG00000112697 E007 522.3531286 7.778223e-05 7.606498e-01 9.148871e-01 6 75254599 75255062 464 - 2.706 2.710 0.015
ENSG00000112697 E008 1225.8159749 2.572633e-05 1.464957e-08 1.238355e-06 6 75255063 75256295 1233 - 3.104 3.061 -0.144
ENSG00000112697 E009 235.2887548 7.558017e-05 2.161760e-08 1.757415e-06 6 75258780 75258986 207 - 2.426 2.317 -0.365
ENSG00000112697 E010 130.4427708 5.205517e-04 1.644460e-05 6.548973e-04 6 75259347 75259441 95 - 2.177 2.058 -0.400
ENSG00000112697 E011 76.6733052 2.338886e-04 7.310866e-03 7.569820e-02 6 75259442 75259490 49 - 1.934 1.841 -0.313
ENSG00000112697 E012 0.1145948 1.119250e-02 3.943492e-01   6 75260122 75260402 281 - 0.109 0.000 -11.176
ENSG00000112697 E013 105.1359494 1.221703e-03 5.154458e-05 1.714471e-03 6 75260824 75260911 88 - 2.091 1.959 -0.441
ENSG00000112697 E014 129.3722083 1.295600e-04 1.476637e-08 1.246244e-06 6 75265231 75265338 108 - 2.190 2.040 -0.503
ENSG00000112697 E015 119.9846721 1.319943e-04 1.131478e-06 6.322698e-05 6 75267641 75267748 108 - 2.149 2.015 -0.450
ENSG00000112697 E016 0.4561064 1.593635e-02 2.131587e-02   6 75272464 75272900 437 - 0.330 0.000 -13.018
ENSG00000112697 E017 0.2279811 1.535146e-02 1.546538e-01   6 75283897 75284014 118 - 0.196 0.000 -12.038
ENSG00000112697 E018 1.2093345 4.698645e-02 2.925866e-01 6.208431e-01 6 75284220 75284401 182 - 0.433 0.265 -1.023
ENSG00000112697 E019 116.7086498 1.366010e-04 1.215883e-03 2.082030e-02 6 75284402 75284496 95 - 2.113 2.023 -0.304
ENSG00000112697 E020 168.6627864 1.077638e-04 3.051162e-11 3.950585e-09 6 75284497 75284948 452 - 2.306 2.152 -0.515

Help

Please Click HERE to learn more details about the results from DEXseq.