ENSG00000112739

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337659 ENSG00000112739 No_inf pgwt_inf PRPF4B protein_coding protein_coding 12.82688 12.92782 12.44988 0.7479194 0.3138717 -0.05430416 2.801930 3.4411491 3.023336 0.3663588 0.4710617 -0.1861716 0.21862500 0.264450 0.243425 -0.021025 1.000000e+00 1.933138e-05 FALSE TRUE
ENST00000480058 ENSG00000112739 No_inf pgwt_inf PRPF4B protein_coding nonsense_mediated_decay 12.82688 12.92782 12.44988 0.7479194 0.3138717 -0.05430416 1.201207 0.0000000 1.262991 0.0000000 0.7308152 6.9920782 0.09480833 0.000000 0.101425 0.101425 9.676424e-01 1.933138e-05 TRUE TRUE
MSTRG.24126.3 ENSG00000112739 No_inf pgwt_inf PRPF4B protein_coding   12.82688 12.92782 12.44988 0.7479194 0.3138717 -0.05430416 2.073357 5.3157793 0.000000 0.6138110 0.0000000 -9.0568488 0.16165833 0.419200 0.000000 -0.419200 1.933138e-05 1.933138e-05 TRUE TRUE
MSTRG.24126.4 ENSG00000112739 No_inf pgwt_inf PRPF4B protein_coding   12.82688 12.92782 12.44988 0.7479194 0.3138717 -0.05430416 1.264098 0.3973176 1.623717 0.3973176 0.9752687 2.0039317 0.09436667 0.026525 0.125025 0.098500 9.928472e-01 1.933138e-05 FALSE TRUE
MSTRG.24126.5 ENSG00000112739 No_inf pgwt_inf PRPF4B protein_coding   12.82688 12.92782 12.44988 0.7479194 0.3138717 -0.05430416 4.089317 2.3279495 4.951201 0.2752775 1.0595856 1.0854457 0.32255000 0.181500 0.403000 0.221500 9.425485e-01 1.933138e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000112739 E001 0.0000000       6 4021267 4021299 33 +      
ENSG00000112739 E002 0.0000000       6 4021300 4021333 34 +      
ENSG00000112739 E003 0.1141751 0.0111878491 4.719390e-01   6 4021334 4021366 33 + 0.101 0.000 -10.587
ENSG00000112739 E004 3.2703418 0.2889110541 4.601928e-01 7.544019e-01 6 4021367 4021442 76 + 0.715 0.547 -0.732
ENSG00000112739 E005 4.7430433 0.1009331586 4.058831e-01 7.155435e-01 6 4021443 4021466 24 + 0.830 0.690 -0.564
ENSG00000112739 E006 75.2257140 0.0002276847 4.598211e-01 7.542320e-01 6 4031559 4032755 1197 + 1.865 1.888 0.077
ENSG00000112739 E007 5.6270700 0.0027311961 4.628409e-01 7.562562e-01 6 4037397 4037418 22 + 0.862 0.781 -0.319
ENSG00000112739 E008 11.6950659 0.0012042089 9.689821e-02 3.585096e-01 6 4037419 4037570 152 + 1.172 1.035 -0.495
ENSG00000112739 E009 6.5862014 0.0023395245 2.351365e-03 3.413304e-02 6 4040772 4040847 76 + 1.029 0.709 -1.233
ENSG00000112739 E010 3.4466668 0.0042791355 5.558277e-03 6.231609e-02 6 4040848 4040848 1 + 0.813 0.452 -1.586
ENSG00000112739 E011 7.9629047 0.0044700046 1.453492e-02 1.181228e-01 6 4040849 4040927 79 + 1.069 0.828 -0.907
ENSG00000112739 E012 11.0353094 0.0031678684 4.559158e-01 7.522000e-01 6 4042487 4042568 82 + 1.039 1.103 0.231
ENSG00000112739 E013 19.9382513 0.0007219664 4.056252e-01 7.153589e-01 6 4043813 4044023 211 + 1.286 1.339 0.185
ENSG00000112739 E014 0.1316618 0.0122516994 6.123866e-01   6 4044024 4044226 203 + 0.000 0.090 12.097
ENSG00000112739 E015 9.3125553 0.0050251660 4.398497e-01 7.405164e-01 6 4047175 4047248 74 + 1.050 0.976 -0.269
ENSG00000112739 E016 11.1865516 0.0027382592 6.497220e-02 2.877265e-01 6 4049016 4049106 91 + 1.165 1.007 -0.572
ENSG00000112739 E017 16.3043584 0.0012759090 3.281225e-02 1.940155e-01 6 4049732 4049879 148 + 1.315 1.162 -0.540
ENSG00000112739 E018 8.3853932 0.0130408640 1.373596e-01 4.292115e-01 6 4051957 4051981 25 + 1.050 0.896 -0.572
ENSG00000112739 E019 11.4598424 0.0190080008 2.223931e-01 5.465468e-01 6 4051982 4052094 113 + 1.157 1.035 -0.439
ENSG00000112739 E020 13.1549941 0.0024467390 7.045495e-01 8.893943e-01 6 4052720 4052873 154 + 1.165 1.133 -0.113
ENSG00000112739 E021 13.3041803 0.0510391791 9.608488e-01 9.906924e-01 6 4056321 4056435 115 + 1.157 1.148 -0.032
ENSG00000112739 E022 0.1315150 0.0123693932 6.121852e-01   6 4056436 4056526 91 + 0.000 0.090 12.097
ENSG00000112739 E023 0.1145948 0.0112981953 4.718592e-01   6 4056527 4056688 162 + 0.101 0.000 -13.314
ENSG00000112739 E024 0.4914338 0.0162740006 8.966785e-01   6 4056689 4057035 347 + 0.183 0.164 -0.193
ENSG00000112739 E025 16.4771119 0.0062673139 7.096951e-01 8.921353e-01 6 4057036 4057159 124 + 1.256 1.225 -0.107
ENSG00000112739 E026 6.2986213 0.0025492667 8.162513e-01 9.372917e-01 6 4057160 4057187 28 + 0.846 0.870 0.090
ENSG00000112739 E027 8.5536951 0.0016605602 3.074340e-01 6.338774e-01 6 4058728 4058814 87 + 1.029 0.932 -0.359
ENSG00000112739 E028 0.1308632 0.0122419390 6.123355e-01   6 4058815 4058890 76 + 0.000 0.090 12.097
ENSG00000112739 E029 20.0567513 0.0008307666 1.412751e-01 4.347150e-01 6 4060413 4060644 232 + 1.371 1.275 -0.334
ENSG00000112739 E030 10.3573540 0.0186611415 9.342568e-01 9.818267e-01 6 4060645 4060686 42 + 1.050 1.053 0.013
ENSG00000112739 E031 26.3347614 0.0005519371 5.301642e-01 7.989184e-01 6 4060687 4060981 295 + 1.413 1.447 0.119
ENSG00000112739 E032 9.1498073 0.0015781928 7.147872e-01 8.941600e-01 6 4060982 4061014 33 + 0.984 1.016 0.120
ENSG00000112739 E033 19.4081700 0.0021618286 5.147085e-01 7.895687e-01 6 4061015 4061147 133 + 1.331 1.286 -0.157
ENSG00000112739 E034 39.9122931 0.0003790316 7.454330e-02 3.102231e-01 6 4061148 4061654 507 + 1.653 1.570 -0.282
ENSG00000112739 E035 9.1588578 0.0014914014 2.542629e-01 5.813256e-01 6 4061655 4061700 46 + 1.060 0.955 -0.386
ENSG00000112739 E036 20.7674451 0.0006891109 5.311676e-01 7.995452e-01 6 4061701 4062103 403 + 1.357 1.316 -0.142
ENSG00000112739 E037 7.8963841 0.0017952419 5.952308e-02 2.742205e-01 6 4062104 4062212 109 + 0.830 1.016 0.705
ENSG00000112739 E038 5.6679484 0.0029807067 3.485494e-02 2.014861e-01 6 4062213 4062299 87 + 0.669 0.908 0.953
ENSG00000112739 E039 4.6972279 0.0030714902 8.074338e-01 9.343120e-01 6 4062300 4062556 257 + 0.736 0.764 0.111
ENSG00000112739 E040 6.2509360 0.0022737539 5.455346e-01 8.083677e-01 6 4062557 4062633 77 + 0.892 0.828 -0.250
ENSG00000112739 E041 3.8306945 0.0037513211 8.630249e-01 9.562227e-01 6 4062634 4062760 127 + 0.669 0.690 0.087
ENSG00000112739 E042 6.6256746 0.0029547427 6.336210e-01 8.540193e-01 6 4062761 4063073 313 + 0.907 0.856 -0.193
ENSG00000112739 E043 3.7682495 0.0038472877 1.408719e-01 4.344123e-01 6 4063074 4063119 46 + 0.558 0.747 0.807
ENSG00000112739 E044 66.7268991 0.0005650209 8.732217e-14 1.587529e-11 6 4063120 4064800 1681 + 1.648 1.926 0.939
ENSG00000112739 E045 6.7190665 0.0021554941 2.581854e-03 3.656891e-02 6 4064801 4064983 183 + 0.669 0.997 1.285

Help

Please Click HERE to learn more details about the results from DEXseq.