ENSG00000113716

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000502717 ENSG00000113716 No_inf pgwt_inf HMGXB3 protein_coding protein_coding 48.1698 42.37862 56.51844 1.420091 2.063441 0.4153 4.420470 0.000000 6.331055 0.0000000 1.5196524 9.30857907 0.08771667 0.000000 0.110750 0.110750 0.0002027873 0.0002027873 FALSE TRUE
ENST00000513318 ENSG00000113716 No_inf pgwt_inf HMGXB3 protein_coding retained_intron 48.1698 42.37862 56.51844 1.420091 2.063441 0.4153 2.658883 3.551976 4.424672 1.2998273 0.8599507 0.31614964 0.05262500 0.080950 0.076925 -0.004025 1.0000000000 0.0002027873   FALSE
MSTRG.23765.10 ENSG00000113716 No_inf pgwt_inf HMGXB3 protein_coding   48.1698 42.37862 56.51844 1.420091 2.063441 0.4153 5.061738 7.059747 4.191913 2.4002907 3.0109559 -0.75061232 0.10895000 0.161800 0.080225 -0.081575 0.9928472467 0.0002027873 FALSE TRUE
MSTRG.23765.3 ENSG00000113716 No_inf pgwt_inf HMGXB3 protein_coding   48.1698 42.37862 56.51844 1.420091 2.063441 0.4153 4.282994 4.193507 4.285261 0.1665314 0.4862374 0.03115227 0.09033333 0.099325 0.075750 -0.023575 0.9928472467 0.0002027873 FALSE TRUE
MSTRG.23765.4 ENSG00000113716 No_inf pgwt_inf HMGXB3 protein_coding   48.1698 42.37862 56.51844 1.420091 2.063441 0.4153 5.209976 5.966226 4.745624 0.3665109 0.4319555 -0.32960013 0.11118333 0.141150 0.084950 -0.056200 0.9928472467 0.0002027873 TRUE TRUE
MSTRG.23765.7 ENSG00000113716 No_inf pgwt_inf HMGXB3 protein_coding   48.1698 42.37862 56.51844 1.420091 2.063441 0.4153 18.715084 13.888765 21.579558 1.0217313 0.9175822 0.63537707 0.38898333 0.330425 0.383250 0.052825 0.9928472467 0.0002027873 FALSE TRUE
MSTRG.23765.9 ENSG00000113716 No_inf pgwt_inf HMGXB3 protein_coding   48.1698 42.37862 56.51844 1.420091 2.063441 0.4153 6.347700 7.320167 7.672380 1.4566562 2.7587899 0.06770720 0.13254167 0.176625 0.131000 -0.045625 0.9928472467 0.0002027873 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000113716 E001 0.0000000       5 150000046 150000055 10 +      
ENSG00000113716 E002 0.0000000       5 150000321 150000372 52 +      
ENSG00000113716 E003 0.0000000       5 150000373 150000453 81 +      
ENSG00000113716 E004 0.2284008 1.546086e-02 3.460604e-01   5 150000454 150000665 212 + 0.155 0.000 -9.491
ENSG00000113716 E005 0.5717655 3.564576e-02 4.382588e-02   5 150000666 150000706 41 + 0.317 0.000 -12.965
ENSG00000113716 E006 2.3871207 9.051293e-03 2.255200e-01 5.497775e-01 5 150000707 150000738 32 + 0.603 0.427 -0.845
ENSG00000113716 E007 25.4778346 2.705494e-03 1.942263e-05 7.520567e-04 5 150000739 150001179 441 + 1.530 1.256 -0.949
ENSG00000113716 E008 16.4092044 7.893412e-03 2.701600e-01 5.982421e-01 5 150004851 150004989 139 + 1.280 1.191 -0.314
ENSG00000113716 E009 19.2209233 3.143743e-03 3.518352e-01 6.720225e-01 5 150006473 150006647 175 + 1.335 1.269 -0.230
ENSG00000113716 E010 32.4891060 8.760517e-04 1.070124e-03 1.890469e-02 5 150010111 150010608 498 + 1.598 1.422 -0.606
ENSG00000113716 E011 10.0388625 1.431919e-03 5.002154e-01 7.806225e-01 5 150012255 150012353 99 + 1.070 1.009 -0.222
ENSG00000113716 E012 12.5366677 1.212188e-03 2.223843e-01 5.465468e-01 5 150018566 150018697 132 + 1.175 1.075 -0.359
ENSG00000113716 E013 0.0000000       5 150023012 150023064 53 +      
ENSG00000113716 E014 14.4680389 9.175959e-04 1.887129e-01 5.030977e-01 5 150024262 150024408 147 + 1.233 1.132 -0.359
ENSG00000113716 E015 7.4441898 3.494969e-03 7.070195e-01 8.906701e-01 5 150024409 150024448 40 + 0.908 0.945 0.141
ENSG00000113716 E016 10.2179162 9.224766e-03 9.199092e-01 9.768032e-01 5 150024449 150024504 56 + 1.045 1.054 0.033
ENSG00000113716 E017 23.7264059 6.157787e-04 3.768792e-03 4.768464e-02 5 150024505 150024680 176 + 1.468 1.288 -0.622
ENSG00000113716 E018 22.2761410 1.409345e-02 1.195593e-01 4.001089e-01 5 150026706 150026881 176 + 1.421 1.294 -0.439
ENSG00000113716 E019 10.7598797 1.835553e-02 4.940545e-01 7.765547e-01 5 150027020 150027062 43 + 1.100 1.032 -0.248
ENSG00000113716 E020 9.6495308 2.933850e-02 3.680446e-01 6.865461e-01 5 150027063 150027117 55 + 1.070 0.972 -0.359
ENSG00000113716 E021 47.8942967 1.125133e-03 2.580772e-10 2.878211e-08 5 150027118 150028513 1396 + 1.532 1.816 0.963
ENSG00000113716 E022 1.7522960 6.302069e-02 1.541827e-01 4.546307e-01 5 150028620 150028680 61 + 0.317 0.545 1.225
ENSG00000113716 E023 60.2332088 1.323207e-03 6.762780e-06 3.006775e-04 5 150028681 150029792 1112 + 1.691 1.873 0.615
ENSG00000113716 E024 10.1512727 1.441372e-03 8.186979e-05 2.504980e-03 5 150029793 150029857 65 + 0.846 1.198 1.298
ENSG00000113716 E025 7.8773900 1.712993e-03 1.554711e-03 2.510903e-02 5 150029858 150029887 30 + 0.774 1.085 1.176
ENSG00000113716 E026 28.3505000 5.170899e-04 8.097967e-09 7.082186e-07 5 150029888 150030316 429 + 1.285 1.609 1.118
ENSG00000113716 E027 28.0655712 1.690985e-03 1.034976e-02 9.479419e-02 5 150030317 150030740 424 + 1.388 1.534 0.504
ENSG00000113716 E028 21.0227463 1.097447e-02 3.225573e-01 6.471334e-01 5 150030741 150030839 99 + 1.376 1.300 -0.263
ENSG00000113716 E029 42.8870828 3.758795e-04 1.057395e-02 9.619482e-02 5 150032454 150032603 150 + 1.693 1.575 -0.403
ENSG00000113716 E030 64.2876212 3.669225e-03 8.445569e-02 3.323510e-01 5 150036636 150036937 302 + 1.849 1.771 -0.262
ENSG00000113716 E031 28.4924057 4.829767e-04 7.592989e-01 9.145805e-01 5 150037400 150037527 128 + 1.461 1.477 0.056
ENSG00000113716 E032 40.5337848 1.050826e-02 4.233756e-01 7.286165e-01 5 150040748 150040879 132 + 1.596 1.640 0.151
ENSG00000113716 E033 51.2081138 3.040462e-04 2.051356e-01 5.249020e-01 5 150041785 150041969 185 + 1.741 1.688 -0.182
ENSG00000113716 E034 69.8461122 2.055758e-04 3.130474e-02 1.890177e-01 5 150045466 150045685 220 + 1.884 1.807 -0.262
ENSG00000113716 E035 1.3415873 3.409662e-02 8.973533e-01 9.692983e-01 5 150047485 150047623 139 + 0.360 0.379 0.115
ENSG00000113716 E036 46.2437579 3.296213e-04 6.361687e-01 8.551518e-01 5 150047624 150047757 134 + 1.684 1.662 -0.073
ENSG00000113716 E037 37.7513654 1.200358e-03 7.152950e-01 8.944515e-01 5 150048569 150048685 117 + 1.579 1.597 0.060
ENSG00000113716 E038 81.3971493 2.310649e-04 1.991863e-01 5.170971e-01 5 150050252 150050461 210 + 1.895 1.936 0.139
ENSG00000113716 E039 340.7347125 6.897306e-05 5.859800e-01 8.301946e-01 5 150051725 150053219 1495 + 2.537 2.528 -0.028

Help

Please Click HERE to learn more details about the results from DEXseq.