ENSG00000114738

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357955 ENSG00000114738 No_inf pgwt_inf MAPKAPK3 protein_coding protein_coding 61.19411 45.51443 60.04753 0.7098994 2.178278 0.3997042 24.983115 15.597867 20.032601 2.640914 2.770170 0.3607963 0.39180000 0.341100 0.331950 -0.009150 1.0000000000 0.0001359962 FALSE TRUE
ENST00000430409 ENSG00000114738 No_inf pgwt_inf MAPKAPK3 protein_coding protein_coding 61.19411 45.51443 60.04753 0.7098994 2.178278 0.3997042 3.951932 0.000000 6.024296 0.000000 1.203695 9.2370417 0.05618333 0.000000 0.098675 0.098675 0.0001359962 0.0001359962 FALSE TRUE
ENST00000451680 ENSG00000114738 No_inf pgwt_inf MAPKAPK3 protein_coding protein_coding 61.19411 45.51443 60.04753 0.7098994 2.178278 0.3997042 2.968222 7.625163 1.279505 1.376129 1.279505 -2.5658420 0.06262500 0.167800 0.020075 -0.147725 0.1644872430 0.0001359962 FALSE TRUE
ENST00000621469 ENSG00000114738 No_inf pgwt_inf MAPKAPK3 protein_coding protein_coding 61.19411 45.51443 60.04753 0.7098994 2.178278 0.3997042 7.015224 7.911709 5.370806 2.832942 3.228778 -0.5579895 0.12560833 0.175575 0.095500 -0.080075 0.9928472467 0.0001359962 FALSE TRUE
MSTRG.20197.4 ENSG00000114738 No_inf pgwt_inf MAPKAPK3 protein_coding   61.19411 45.51443 60.04753 0.7098994 2.178278 0.3997042 17.548390 12.359547 24.267614 2.973944 2.060031 0.9728340 0.29400000 0.271125 0.402950 0.131825 0.9928472467 0.0001359962 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000114738 E001 0.0000000       3 50611520 50611737 218 +      
ENSG00000114738 E002 0.0000000       3 50611908 50611993 86 +      
ENSG00000114738 E003 0.1315150 0.0122552829 4.100893e-01   3 50611994 50612129 136 + 0.000 0.107 10.155
ENSG00000114738 E004 0.0000000       3 50612328 50612699 372 +      
ENSG00000114738 E005 0.1315150 0.0122552829 4.100893e-01   3 50612848 50612942 95 + 0.000 0.107 12.038
ENSG00000114738 E006 0.5255549 0.0159456670 2.340047e-02   3 50613792 50614018 227 + 0.000 0.327 13.941
ENSG00000114738 E007 0.2625250 0.0160774522 1.637257e-01   3 50614019 50614117 99 + 0.000 0.193 12.976
ENSG00000114738 E008 0.2620121 0.0160563386 1.637115e-01   3 50617122 50617130 9 + 0.000 0.193 12.976
ENSG00000114738 E009 1.4214020 0.0260249685 2.009168e-01 0.5196525233 3 50617131 50617150 20 + 0.466 0.265 -1.192
ENSG00000114738 E010 4.3822060 0.0034381106 8.964094e-01 0.9688258688 3 50617151 50617169 19 + 0.722 0.739 0.071
ENSG00000114738 E011 9.0379708 0.0015845960 2.935475e-01 0.6219283655 3 50617170 50617226 57 + 1.043 0.947 -0.355
ENSG00000114738 E012 2.4993422 0.0057565792 1.675788e-01 0.4742113945 3 50617227 50617241 15 + 0.624 0.429 -0.929
ENSG00000114738 E013 0.8491254 0.0138574235 9.791606e-01 0.9973230220 3 50617390 50617513 124 + 0.268 0.265 -0.022
ENSG00000114738 E014 27.6834079 0.0029908117 8.142351e-01 0.9366469605 3 50617514 50617709 196 + 1.462 1.450 -0.041
ENSG00000114738 E015 25.0667109 0.0006123797 4.186584e-01 0.7249771847 3 50617710 50617784 75 + 1.436 1.390 -0.158
ENSG00000114738 E016 0.4737217 0.0219784964 4.664560e-01   3 50627820 50628002 183 + 0.215 0.107 -1.192
ENSG00000114738 E017 43.8767086 0.0003345779 3.917809e-01 0.7053991518 3 50640366 50640505 140 + 1.668 1.631 -0.123
ENSG00000114738 E018 36.7431330 0.0004329276 8.083096e-01 0.9347549412 3 50641707 50641771 65 + 1.570 1.583 0.047
ENSG00000114738 E019 46.1973245 0.0034539329 5.626998e-01 0.8174114410 3 50642253 50642332 80 + 1.685 1.659 -0.089
ENSG00000114738 E020 56.0079371 0.0003184051 1.309507e-01 0.4196839282 3 50644409 50644532 124 + 1.781 1.723 -0.195
ENSG00000114738 E021 34.4749546 0.0064716028 6.559870e-01 0.8658095953 3 50645710 50645785 76 + 1.536 1.564 0.096
ENSG00000114738 E022 36.5022140 0.0043761190 5.721775e-01 0.8229373032 3 50646140 50646211 72 + 1.587 1.557 -0.101
ENSG00000114738 E023 34.1753750 0.0004172436 7.721431e-04 0.0147128458 3 50646212 50646264 53 + 1.617 1.446 -0.585
ENSG00000114738 E024 37.3476170 0.0004073478 2.382372e-02 0.1604902802 3 50646740 50646825 86 + 1.630 1.522 -0.369
ENSG00000114738 E025 32.9525789 0.0005973457 3.949747e-01 0.7078396741 3 50647123 50647203 81 + 1.549 1.507 -0.144
ENSG00000114738 E026 0.0000000       3 50647204 50647204 1 +      
ENSG00000114738 E027 354.4578088 0.0001443445 3.180854e-06 0.0001556302 3 50647894 50649291 1398 + 2.521 2.580 0.197

Help

Please Click HERE to learn more details about the results from DEXseq.