ENSG00000114978

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396049 ENSG00000114978 No_inf pgwt_inf MOB1A protein_coding protein_coding 88.82182 47.18058 99.20639 0.6089189 2.689262 1.072079 61.619564 39.373404 68.16324 5.470409 1.022027 0.7916178 0.72186667 0.8324 0.689200 -0.143200 9.266828e-01 3.984009e-06 FALSE TRUE
ENST00000497054 ENSG00000114978 No_inf pgwt_inf MOB1A protein_coding protein_coding_CDS_not_defined 88.82182 47.18058 99.20639 0.6089189 2.689262 1.072079 14.710450 0.000000 14.33149 0.000000 2.537923 10.4859788 0.13050000 0.0000 0.142825 0.142825 2.080904e-05 3.984009e-06 FALSE TRUE
MSTRG.16515.2 ENSG00000114978 No_inf pgwt_inf MOB1A protein_coding   88.82182 47.18058 99.20639 0.6089189 2.689262 1.072079 1.919797 5.759392 0.00000 5.759392 0.000000 -9.1722755 0.04150000 0.1245 0.000000 -0.124500 9.928472e-01 3.984009e-06 FALSE TRUE
MSTRG.16515.4 ENSG00000114978 No_inf pgwt_inf MOB1A protein_coding   88.82182 47.18058 99.20639 0.6089189 2.689262 1.072079 8.182074 0.000000 15.29030 0.000000 1.622030 10.5793438 0.07676667 0.0000 0.154000 0.154000 3.984009e-06 3.984009e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000114978 E001 0.2449549 1.640615e-02 7.135417e-01   2 74152528 74152597 70 - 0.077 0.117 0.686
ENSG00000114978 E002 1118.0957618 7.509218e-05 8.053659e-30 5.089721e-27 2 74152598 74156354 3757 - 3.014 3.080 0.218
ENSG00000114978 E003 164.8649096 9.256736e-05 9.261955e-03 8.844759e-02 2 74156355 74156645 291 - 2.238 2.178 -0.199
ENSG00000114978 E004 3.1664315 4.446613e-03 2.679664e-02 1.727005e-01 2 74158654 74158771 118 - 0.720 0.407 -1.452
ENSG00000114978 E005 0.1138060 1.116810e-02 9.030539e-01   2 74159069 74159090 22 - 0.077 0.000 -8.771
ENSG00000114978 E006 26.8497250 5.590936e-04 1.284783e-01 4.157300e-01 2 74159091 74159108 18 - 1.474 1.385 -0.304
ENSG00000114978 E007 77.3467378 2.010301e-04 1.436857e-02 1.174010e-01 2 74159109 74159254 146 - 1.921 1.837 -0.284
ENSG00000114978 E008 1.0782419 1.146672e-02 7.547787e-01 9.127148e-01 2 74164022 74165217 1196 - 0.334 0.286 -0.314
ENSG00000114978 E009 76.9783611 1.514403e-03 7.865264e-02 3.199996e-01 2 74165218 74165351 134 - 1.912 1.847 -0.221
ENSG00000114978 E010 69.5438887 2.145732e-04 3.029739e-03 4.100886e-02 2 74167014 74167107 94 - 1.885 1.776 -0.367
ENSG00000114978 E011 72.8793922 1.561254e-03 4.839365e-06 2.251556e-04 2 74172586 74172675 90 - 1.929 1.748 -0.611
ENSG00000114978 E012 53.5478303 2.519879e-04 2.009777e-07 1.320434e-05 2 74172676 74172749 74 - 1.811 1.586 -0.762
ENSG00000114978 E013 21.8104522 6.377295e-04 1.229147e-02 1.061675e-01 2 74172750 74172752 3 - 1.413 1.250 -0.570
ENSG00000114978 E014 0.4907892 1.594044e-02 6.402597e-01   2 74178008 74178114 107 - 0.142 0.210 0.686
ENSG00000114978 E015 0.8506513 2.524208e-01 9.301278e-01 9.804503e-01 2 74178115 74178281 167 - 0.248 0.286 0.272
ENSG00000114978 E016 0.0000000       2 74178282 74178314 33 -      
ENSG00000114978 E017 64.9963794 8.350410e-04 4.338875e-06 2.049230e-04 2 74178661 74178898 238 - 1.881 1.697 -0.623

Help

Please Click HERE to learn more details about the results from DEXseq.