ENSG00000115053

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000494618 ENSG00000115053 No_inf pgwt_inf NCL protein_coding retained_intron 317.3441 197.1358 367.729 2.245043 5.113359 0.8994191 37.47097 28.31304 41.77619 3.676175 6.888934 0.5610499 0.1215583 0.143225 0.113100 -0.030125 9.928472e-01 3.344217e-09 FALSE TRUE
ENST00000676690 ENSG00000115053 No_inf pgwt_inf NCL protein_coding protein_coding 317.3441 197.1358 367.729 2.245043 5.113359 0.8994191 44.51793 0.00000 69.22149 0.000000 10.935274 12.7572128 0.1183167 0.000000 0.188375 0.188375 3.344217e-09 3.344217e-09 FALSE TRUE
ENST00000677703 ENSG00000115053 No_inf pgwt_inf NCL protein_coding retained_intron 317.3441 197.1358 367.729 2.245043 5.113359 0.8994191 20.47647 16.50166 24.45495 5.947020 5.678557 0.5672310 0.0679000 0.083950 0.066425 -0.017525 1.000000e+00 3.344217e-09 FALSE TRUE
ENST00000678246 ENSG00000115053 No_inf pgwt_inf NCL protein_coding protein_coding 317.3441 197.1358 367.729 2.245043 5.113359 0.8994191 66.82109 60.54116 52.49608 4.703551 10.245352 -0.2056701 0.2254917 0.306950 0.143750 -0.163200 7.978201e-01 3.344217e-09 FALSE TRUE
ENST00000679348 ENSG00000115053 No_inf pgwt_inf NCL protein_coding protein_coding 317.3441 197.1358 367.729 2.245043 5.113359 0.8994191 113.20547 76.96862 127.64126 3.991230 6.126306 0.7296781 0.3623167 0.391050 0.347675 -0.043375 9.929037e-01 3.344217e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000115053 E001 3.6280842 5.823675e-03 0.6428356098 0.859068170 2 231453531 231454747 1217 - 0.633 0.693 0.253
ENSG00000115053 E002 0.3591300 1.677435e-02 1.0000000000   2 231454748 231454748 1 - 0.136 0.123 -0.162
ENSG00000115053 E003 1.7973741 8.341056e-03 0.8401611762 0.947058993 2 231454749 231454750 2 - 0.452 0.421 -0.162
ENSG00000115053 E004 2.0601848 1.179804e-02 0.6583786237 0.866642877 2 231454751 231454751 1 - 0.452 0.517 0.323
ENSG00000115053 E005 21.8378719 9.924162e-04 0.0001531387 0.004132954 2 231454752 231454807 56 - 1.238 1.479 0.838
ENSG00000115053 E006 42.6753006 3.780718e-04 0.0002738264 0.006619467 2 231454808 231454878 71 - 1.556 1.725 0.573
ENSG00000115053 E007 22.9330121 6.277555e-04 0.0949868907 0.354355171 2 231454879 231454894 16 - 1.325 1.429 0.360
ENSG00000115053 E008 32.7288060 4.478031e-04 0.0768969499 0.315638404 2 231454895 231454907 13 - 1.479 1.572 0.319
ENSG00000115053 E009 446.3336343 2.049015e-04 0.1853978280 0.499112145 2 231454908 231455190 283 - 2.632 2.652 0.065
ENSG00000115053 E010 226.6819491 9.417440e-05 0.5931384408 0.834107037 2 231455191 231455258 68 - 2.343 2.353 0.035
ENSG00000115053 E011 101.2035079 1.706971e-04 0.8538922192 0.952425145 2 231455259 231455261 3 - 1.997 2.002 0.017
ENSG00000115053 E012 102.1380676 1.056623e-03 0.9572317434 0.989458191 2 231455262 231455267 6 - 2.003 2.004 0.003
ENSG00000115053 E013 0.7350922 1.445454e-02 0.4836805782 0.770284609 2 231455268 231455275 8 - 0.190 0.297 0.838
ENSG00000115053 E014 1.4368586 9.979089e-03 0.8578252454 0.954153528 2 231455276 231455400 125 - 0.392 0.363 -0.162
ENSG00000115053 E015 137.2687551 1.903065e-04 0.6074789867 0.841385658 2 231455401 231455457 57 - 2.125 2.138 0.044
ENSG00000115053 E016 199.7701231 9.401494e-05 0.3127483428 0.638613763 2 231455458 231455572 115 - 2.284 2.305 0.072
ENSG00000115053 E017 139.7752177 3.951397e-04 0.9776589989 0.996769673 2 231455573 231455624 52 - 2.139 2.137 -0.005
ENSG00000115053 E018 1.7177372 7.941215e-03 0.2855056436 0.613222803 2 231455625 231455799 175 - 0.358 0.517 0.838
ENSG00000115053 E019 0.8845460 1.334231e-02 0.0584945204 0.271448391 2 231455800 231455827 28 - 0.136 0.421 2.160
ENSG00000115053 E020 1.1121579 8.165661e-02 0.2630811620 0.591165011 2 231455828 231455904 77 - 0.239 0.421 1.160
ENSG00000115053 E021 1.4397801 3.956965e-01 0.6865264262 0.880379693 2 231455905 231456009 105 - 0.392 0.364 -0.161
ENSG00000115053 E022 262.6647083 7.216271e-05 0.1088193840 0.380778183 2 231456010 231456136 127 - 2.423 2.391 -0.105
ENSG00000115053 E023 0.2456120 1.605493e-02 0.6502947436   2 231456137 231456159 23 - 0.073 0.123 0.838
ENSG00000115053 E024 2.0798537 1.235114e-01 0.4814115941 0.768769843 2 231456160 231456443 284 - 0.423 0.559 0.668
ENSG00000115053 E025 2.4043124 2.000290e-02 0.9422556803 0.985396996 2 231456444 231456630 187 - 0.529 0.517 -0.055
ENSG00000115053 E026 286.4937728 6.393079e-05 0.5754753399 0.824735739 2 231456631 231456764 134 - 2.444 2.454 0.032
ENSG00000115053 E027 0.3594082 1.675612e-02 1.0000000000   2 231456765 231457000 236 - 0.136 0.123 -0.162
ENSG00000115053 E028 265.3492482 2.622410e-04 0.3734265519 0.691231943 2 231457001 231457124 124 - 2.422 2.404 -0.062
ENSG00000115053 E029 4.8238713 2.881928e-03 0.8294878860 0.942596127 2 231457125 231457285 161 - 0.747 0.772 0.101
ENSG00000115053 E030 3.7270419 8.593660e-02 0.9737495721 0.995483463 2 231457286 231457357 72 - 0.669 0.663 -0.024
ENSG00000115053 E031 2.8317365 8.260757e-02 0.2038631963 0.522840796 2 231457358 231457425 68 - 0.479 0.693 0.964
ENSG00000115053 E032 7.2466915 3.096527e-03 0.0212202228 0.149481561 2 231457426 231457642 217 - 0.800 1.034 0.887
ENSG00000115053 E033 402.0476757 4.936799e-05 0.3705919555 0.689006120 2 231457643 231457800 158 - 2.601 2.586 -0.048
ENSG00000115053 E034 3.2705305 4.620578e-03 0.6038687399 0.839244141 2 231457801 231458265 465 - 0.594 0.663 0.297
ENSG00000115053 E035 298.7417408 5.396326e-04 0.4594370735 0.754100055 2 231458266 231458344 79 - 2.461 2.475 0.047
ENSG00000115053 E036 215.5224072 8.133491e-05 0.0886664161 0.341684385 2 231458345 231458389 45 - 2.311 2.346 0.118
ENSG00000115053 E037 5.2290355 1.489540e-01 0.4219846705 0.727754455 2 231458390 231458620 231 - 0.732 0.858 0.501
ENSG00000115053 E038 8.5704396 1.614984e-03 0.0314752823 0.189637593 2 231458621 231459000 380 - 0.880 1.084 0.755
ENSG00000115053 E039 338.4898589 5.983283e-05 0.2346634436 0.559804260 2 231459001 231459125 125 - 2.513 2.532 0.064
ENSG00000115053 E040 339.1445853 2.059611e-04 0.5034552503 0.782741948 2 231460152 231460293 142 - 2.526 2.514 -0.041
ENSG00000115053 E041 269.4304420 6.404091e-04 0.4294308416 0.732920707 2 231460478 231460564 87 - 2.428 2.411 -0.058
ENSG00000115053 E042 383.3995939 6.326778e-05 0.1490602670 0.446331622 2 231460669 231460866 198 - 2.583 2.560 -0.078
ENSG00000115053 E043 0.3773519 1.685106e-02 0.2862389789   2 231460867 231461171 305 - 0.073 0.219 1.838
ENSG00000115053 E044 534.4824764 2.778264e-04 0.3419673714 0.663619551 2 231461540 231462017 478 - 2.724 2.709 -0.048
ENSG00000115053 E045 0.1138060 1.105694e-02 1.0000000000   2 231462992 231463199 208 - 0.073 0.000 -10.319
ENSG00000115053 E046 171.4343797 1.112815e-03 0.0010174019 0.018213614 2 231463200 231463312 113 - 2.260 2.168 -0.307
ENSG00000115053 E047 50.9038981 2.939455e-04 0.2136084341 0.535645599 2 231463313 231463316 4 - 1.726 1.670 -0.188
ENSG00000115053 E048 0.0000000       2 231463586 231463700 115 -      
ENSG00000115053 E049 1.1431749 9.050045e-02 0.0122075377 0.105803975 2 231463701 231464142 442 - 0.452 0.000 -12.793
ENSG00000115053 E050 2.1085679 2.252988e-02 0.0835557967 0.330634313 2 231464143 231464159 17 - 0.574 0.297 -1.484
ENSG00000115053 E051 1.3258685 2.053611e-02 0.9706198852 0.994503664 2 231464160 231464335 176 - 0.358 0.363 0.030
ENSG00000115053 E052 116.1258268 1.000300e-03 0.1343244623 0.424752705 2 231464336 231464551 216 - 2.077 2.028 -0.162
ENSG00000115053 E053 0.4562506 4.399142e-02 0.1583242790   2 231482684 231483641 958 - 0.239 0.000 -11.836

Help

Please Click HERE to learn more details about the results from DEXseq.