ENSG00000115306

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000333896 ENSG00000115306 No_inf pgwt_inf SPTBN1 protein_coding protein_coding 13.74535 26.79392 6.484068 0.5426933 0.1271495 -2.045249 0.2061387 0.000000 0.3943139 0.0000000 0.07864746 5.3374039 0.02963333 0.000000 0.060850 0.060850 2.935686e-02 1.505308e-05 FALSE TRUE
ENST00000356805 ENSG00000115306 No_inf pgwt_inf SPTBN1 protein_coding protein_coding 13.74535 26.79392 6.484068 0.5426933 0.1271495 -2.045249 5.1596531 13.739572 0.0000000 0.9038185 0.00000000 -10.4251710 0.24314167 0.513425 0.000000 -0.513425 1.505308e-05 1.505308e-05 FALSE TRUE
ENST00000467371 ENSG00000115306 No_inf pgwt_inf SPTBN1 protein_coding retained_intron 13.74535 26.79392 6.484068 0.5426933 0.1271495 -2.045249 2.7387055 7.061648 0.4865750 0.2627687 0.16637850 -3.8319629 0.14080833 0.263350 0.074875 -0.188475 4.992274e-01 1.505308e-05 FALSE TRUE
ENST00000496323 ENSG00000115306 No_inf pgwt_inf SPTBN1 protein_coding retained_intron 13.74535 26.79392 6.484068 0.5426933 0.1271495 -2.045249 0.7377649 2.213295 0.0000000 0.2694981 0.00000000 -7.7965553 0.02754167 0.082625 0.000000 -0.082625 1.880816e-01 1.505308e-05 FALSE TRUE
MSTRG.16267.5 ENSG00000115306 No_inf pgwt_inf SPTBN1 protein_coding   13.74535 26.79392 6.484068 0.5426933 0.1271495 -2.045249 4.8812039 3.713765 5.6031794 0.7914020 0.26154747 0.5920562 0.55807500 0.138175 0.864275 0.726100 2.418172e-05 1.505308e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000115306 E001 0.0000000       2 54456317 54456326 10 +      
ENSG00000115306 E002 0.7857505 0.3196527725 3.453046e-01 6.667416e-01 2 54456327 54456518 192 + 0.000 0.253 10.339
ENSG00000115306 E003 0.1315150 0.0122290278 1.000000e+00   2 54457261 54457307 47 + 0.000 0.054 10.714
ENSG00000115306 E004 0.0000000       2 54515744 54516341 598 +      
ENSG00000115306 E005 3.4127206 0.0045061853 6.286247e-04 1.258340e-02 2 54526372 54526566 195 + 0.000 0.647 15.090
ENSG00000115306 E006 0.6567038 0.0143325590 2.987898e-01 6.262855e-01 2 54526567 54528715 2149 + 0.000 0.220 12.935
ENSG00000115306 E007 4.5293242 0.0170421205 3.458982e-04 7.921636e-03 2 54558394 54558887 494 + 0.984 0.528 -1.861
ENSG00000115306 E008 4.7984257 0.0103302527 3.746919e-01 6.922907e-01 2 54599092 54599243 152 + 0.778 0.659 -0.487
ENSG00000115306 E009 6.0492316 0.0027504199 1.686001e-01 4.754133e-01 2 54612161 54612334 174 + 0.893 0.729 -0.645
ENSG00000115306 E010 4.9486555 0.0120206319 6.612188e-01 8.677603e-01 2 54616207 54616298 92 + 0.744 0.684 -0.247
ENSG00000115306 E011 6.1424939 0.0118006197 6.604933e-02 2.906652e-01 2 54617608 54617688 81 + 0.941 0.718 -0.870
ENSG00000115306 E012 7.7505742 0.0816880432 8.668993e-02 3.373421e-01 2 54618078 54618193 116 + 1.059 0.789 -1.021
ENSG00000115306 E013 6.7162142 0.0188558718 6.204201e-03 6.753254e-02 2 54621400 54621512 113 + 1.041 0.718 -1.242
ENSG00000115306 E014 9.1268765 0.0096602658 4.717979e-01 7.622655e-01 2 54622300 54622487 188 + 0.984 0.903 -0.303
ENSG00000115306 E015 6.8615037 0.0215178934 1.885396e-02 1.389534e-01 2 54623479 54623596 118 + 1.023 0.739 -1.087
ENSG00000115306 E016 9.4803085 0.0618421436 2.171146e-02 1.514724e-01 2 54624804 54624962 159 + 1.151 0.858 -1.086
ENSG00000115306 E017 13.0835100 0.0013382732 1.646489e-04 4.381230e-03 2 54625932 54626234 303 + 1.293 0.975 -1.140
ENSG00000115306 E018 7.3825969 0.0030507090 2.501934e-02 1.657114e-01 2 54628097 54628250 154 + 1.023 0.779 -0.927
ENSG00000115306 E019 22.7930759 0.0010280795 1.435528e-01 4.382954e-01 2 54628933 54629536 604 + 1.366 1.262 -0.364
ENSG00000115306 E020 14.5472592 0.0064737665 8.900910e-01 9.661474e-01 2 54629537 54629803 267 + 1.092 1.105 0.049
ENSG00000115306 E021 10.4096576 0.0031917707 5.189396e-01 7.919037e-01 2 54629892 54630029 138 + 1.023 0.957 -0.244
ENSG00000115306 E022 45.2632596 0.0004177834 8.931436e-02 3.430745e-01 2 54630855 54631611 757 + 1.640 1.553 -0.298
ENSG00000115306 E023 18.2050706 0.0008392559 9.816839e-02 3.612232e-01 2 54632566 54632768 203 + 1.293 1.164 -0.454
ENSG00000115306 E024 11.2242652 0.0012552147 9.083802e-02 3.461508e-01 2 54637713 54637803 91 + 1.123 0.963 -0.583
ENSG00000115306 E025 12.8323780 0.0010879271 6.011109e-01 8.381419e-01 2 54642983 54643129 147 + 1.092 1.043 -0.179
ENSG00000115306 E026 20.5916840 0.0012952075 5.200158e-01 7.925398e-01 2 54644323 54644586 264 + 1.283 1.233 -0.174
ENSG00000115306 E027 0.0000000       2 54644587 54644590 4 +      
ENSG00000115306 E028 0.0000000       2 54645157 54645158 2 +      
ENSG00000115306 E029 24.1154737 0.0005989820 7.775482e-01 9.227114e-01 2 54645229 54645453 225 + 1.293 1.312 0.069
ENSG00000115306 E030 16.8667391 0.0008349677 5.605983e-01 8.163692e-01 2 54645928 54646017 90 + 1.123 1.172 0.177
ENSG00000115306 E031 29.8492309 0.0004804467 7.808359e-01 9.241319e-01 2 54646194 54646475 282 + 1.383 1.401 0.061
ENSG00000115306 E032 16.5033821 0.0008987824 3.813554e-01 6.975768e-01 2 54647131 54647261 131 + 1.092 1.168 0.274
ENSG00000115306 E033 24.7261828 0.0005561031 2.347206e-01 5.598123e-01 2 54648986 54649184 199 + 1.383 1.301 -0.285
ENSG00000115306 E034 7.9452159 0.0017739979 1.650079e-01 4.704232e-01 2 54649185 54649190 6 + 0.984 0.833 -0.571
ENSG00000115306 E035 0.0000000       2 54649572 54649577 6 +      
ENSG00000115306 E036 45.2102729 0.0063885323 3.447412e-01 6.661664e-01 2 54649615 54649989 375 + 1.617 1.559 -0.198
ENSG00000115306 E037 0.2626639 0.0160106505 1.000000e+00   2 54652518 54653608 1091 + 0.000 0.102 11.667
ENSG00000115306 E038 31.6149943 0.0004781149 8.881614e-01 9.653513e-01 2 54653609 54653853 245 + 1.415 1.423 0.029
ENSG00000115306 E039 31.1890853 0.0004862956 7.874545e-01 9.263667e-01 2 54655070 54655208 139 + 1.430 1.412 -0.061
ENSG00000115306 E040 29.6402506 0.0074691696 5.434000e-01 8.071881e-01 2 54655914 54655998 85 + 1.358 1.403 0.156
ENSG00000115306 E041 43.8629846 0.0050787183 2.725103e-01 6.007323e-01 2 54657850 54658046 197 + 1.504 1.572 0.233
ENSG00000115306 E042 29.3514405 0.0004915432 1.169803e-01 3.956684e-01 2 54659154 54659266 113 + 1.303 1.410 0.372
ENSG00000115306 E043 24.5206935 0.0005796547 4.434251e-01 7.433069e-01 2 54659936 54659999 64 + 1.358 1.304 -0.188
ENSG00000115306 E044 17.2296020 0.0048043834 5.683743e-02 2.665435e-01 2 54660000 54662308 2309 + 1.023 1.202 0.645
ENSG00000115306 E045 21.5756067 0.0006586118 3.810094e-07 2.349160e-05 2 54662901 54664452 1552 + 0.839 1.326 1.774
ENSG00000115306 E046 25.5094719 0.0005454918 8.528536e-01 9.519667e-01 2 54664453 54664691 239 + 1.322 1.334 0.043
ENSG00000115306 E047 30.7325738 0.0004679563 3.248477e-01 6.492551e-01 2 54665915 54666088 174 + 1.458 1.396 -0.213
ENSG00000115306 E048 21.2449251 0.0011186901 6.666849e-01 8.706985e-01 2 54667604 54667646 43 + 1.282 1.250 -0.116
ENSG00000115306 E049 276.2169481 0.0001015183 1.180091e-08 1.010424e-06 2 54668351 54671446 3096 + 2.253 2.369 0.387

Help

Please Click HERE to learn more details about the results from DEXseq.