ENSG00000115762

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000438882 ENSG00000115762 No_inf pgwt_inf PLEKHB2 protein_coding protein_coding 63.1439 41.70402 68.57402 1.316899 1.622452 0.7173402 5.882676 17.648028 0.000000 2.386461 0.000000 -10.7861085 0.14178333 0.425350 0.000000 -0.42535 3.700517e-09 3.700517e-09 FALSE TRUE
ENST00000628582 ENSG00000115762 No_inf pgwt_inf PLEKHB2 protein_coding protein_coding 63.1439 41.70402 68.57402 1.316899 1.622452 0.7173402 3.128755 3.048839 3.309148 1.760373 1.912469 0.1178289 0.05226667 0.069525 0.049725 -0.01980 1.000000e+00 3.700517e-09 FALSE TRUE
ENST00000693505 ENSG00000115762 No_inf pgwt_inf PLEKHB2 protein_coding protein_coding 63.1439 41.70402 68.57402 1.316899 1.622452 0.7173402 48.997184 17.178968 59.874866 2.146288 2.837657 1.8007085 0.72277500 0.411975 0.872025 0.46005 1.325579e-02 3.700517e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000115762 E001 0.0000000       2 131104847 131104943 97 +      
ENSG00000115762 E002 0.0000000       2 131104944 131105301 358 +      
ENSG00000115762 E003 1.0605626 1.307476e-02 3.276265e-01 6.519336e-01 2 131105302 131105328 27 + 0.367 0.212 -1.077
ENSG00000115762 E004 1.0605626 1.307476e-02 3.276265e-01 6.519336e-01 2 131105329 131105335 7 + 0.367 0.212 -1.077
ENSG00000115762 E005 6.0606356 2.328351e-03 1.297535e-01 4.179922e-01 2 131105336 131105352 17 + 0.905 0.734 -0.672
ENSG00000115762 E006 14.7544503 9.238923e-04 2.868958e-02 1.791938e-01 2 131105353 131105398 46 + 1.253 1.080 -0.616
ENSG00000115762 E007 0.7192760 1.425771e-02 8.284140e-01 9.422103e-01 2 131107461 131107555 95 + 0.246 0.212 -0.270
ENSG00000115762 E008 2.1120118 6.474979e-03 8.073327e-02 3.246592e-01 2 131107556 131108064 509 + 0.367 0.618 1.245
ENSG00000115762 E009 0.3761872 1.679968e-02 3.177763e-01   2 131118891 131118978 88 + 0.076 0.212 1.728
ENSG00000115762 E010 0.6229665 3.418204e-01 5.155422e-01   2 131120235 131120933 699 + 0.140 0.289 1.315
ENSG00000115762 E011 22.6060759 6.535434e-04 9.357309e-02 3.517256e-01 2 131120934 131120978 45 + 1.407 1.299 -0.374
ENSG00000115762 E012 48.4673754 2.876560e-04 1.188183e-01 3.988931e-01 2 131125753 131125905 153 + 1.714 1.645 -0.233
ENSG00000115762 E013 40.8547721 3.461460e-04 1.009382e-02 9.330328e-02 2 131126684 131126786 103 + 1.661 1.537 -0.425
ENSG00000115762 E014 0.8508389 1.722960e-02 7.796678e-01 9.237247e-01 2 131126787 131127059 273 + 0.246 0.289 0.315
ENSG00000115762 E015 26.4072691 5.613313e-04 4.738118e-02 2.399158e-01 2 131130721 131130760 40 + 1.476 1.357 -0.409
ENSG00000115762 E016 32.2445331 3.790337e-03 1.396850e-04 3.850112e-03 2 131132902 131132991 90 + 1.595 1.363 -0.799
ENSG00000115762 E017 1.3079182 1.119554e-01 5.473897e-01 8.093092e-01 2 131132992 131133015 24 + 0.402 0.289 -0.685
ENSG00000115762 E018 11.2010543 2.395169e-03 1.465895e-03 2.398105e-02 2 131140167 131140169 3 + 1.178 0.882 -1.087
ENSG00000115762 E019 28.9836293 4.907566e-04 1.339156e-02 1.122008e-01 2 131140170 131140275 106 + 1.523 1.381 -0.489
ENSG00000115762 E020 4.9762173 3.001347e-03 4.690245e-03 5.570518e-02 2 131144408 131144449 42 + 0.607 0.933 1.315
ENSG00000115762 E021 909.8739183 4.686556e-05 4.582921e-12 6.470451e-10 2 131146637 131149852 3216 + 2.939 2.971 0.109
ENSG00000115762 E022 0.0000000       2 131353020 131353709 690 +      

Help

Please Click HERE to learn more details about the results from DEXseq.