ENSG00000116667

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000235307 ENSG00000116667 No_inf pgwt_inf C1orf21 protein_coding protein_coding 12.83219 2.336473 19.39036 0.02529287 2.34068 3.047518 5.964196 2.284019 8.792079 0.04148555 0.135801 1.939967 0.6206917 0.9775 0.47205 -0.50545 0.019047354 0.002815486 FALSE TRUE
ENST00000477517 ENSG00000116667 No_inf pgwt_inf C1orf21 protein_coding protein_coding_CDS_not_defined 12.83219 2.336473 19.39036 0.02529287 2.34068 3.047518 6.799227 0.000000 10.473429 0.00000000 2.326229 10.033895 0.3687583 0.0000 0.52060 0.52060 0.002815486 0.002815486   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000116667 E001 4.1128816 0.0035039380 0.9753325135 0.995740256 1 184387029 184387270 242 + 0.644 0.648 0.019
ENSG00000116667 E002 2.2540585 0.0070852153 0.4950068462 0.776959512 1 184387271 184387288 18 + 0.432 0.540 0.533
ENSG00000116667 E003 14.2201716 0.0009891273 0.9899225143 1.000000000 1 184387289 184387368 80 + 1.107 1.108 0.004
ENSG00000116667 E004 32.0157879 0.0004575028 0.5257384408 0.796045376 1 184477386 184477507 122 + 1.449 1.409 -0.138
ENSG00000116667 E005 35.1175048 0.0004676675 0.2032954097 0.522400892 1 184477508 184477603 96 + 1.495 1.417 -0.269
ENSG00000116667 E006 0.2281253 0.0154359369 1.0000000000   1 184504537 184504751 215 + 0.095 0.000 -9.012
ENSG00000116667 E007 0.5878162 0.0154922453 1.0000000000   1 184506722 184506916 195 + 0.172 0.174 0.019
ENSG00000116667 E008 20.0705032 0.0009339817 0.7191091622 0.896932853 1 184507588 184507597 10 + 1.253 1.225 -0.100
ENSG00000116667 E009 43.8267569 0.0004701539 0.2738121633 0.602062399 1 184507598 184507682 85 + 1.585 1.525 -0.204
ENSG00000116667 E010 1.0803569 0.0129296981 0.3448494343 0.666241346 1 184509310 184509452 143 + 0.238 0.394 1.019
ENSG00000116667 E011 0.0000000       1 184539993 184540101 109 +      
ENSG00000116667 E012 0.0000000       1 184542546 184542648 103 +      
ENSG00000116667 E013 0.1141751 0.0112141458 1.0000000000   1 184545920 184546032 113 + 0.050 0.000 -8.086
ENSG00000116667 E014 0.1138060 0.0111806198 1.0000000000   1 184568399 184568485 87 + 0.050 0.000 -8.086
ENSG00000116667 E015 23.4282208 0.0008040802 0.4025996072 0.713357113 1 184590739 184590747 9 + 1.324 1.261 -0.218
ENSG00000116667 E016 42.9620603 0.0003419713 0.1821204890 0.494833057 1 184590748 184590815 68 + 1.579 1.506 -0.252
ENSG00000116667 E017 0.0000000       1 184592225 184592290 66 +      
ENSG00000116667 E018 35.3115314 0.0005673674 0.0089854019 0.086522591 1 184598401 184598461 61 + 1.513 1.346 -0.577
ENSG00000116667 E019 0.0000000       1 184599340 184599609 270 +      
ENSG00000116667 E020 200.0892179 0.0001350146 0.0000348747 0.001233417 1 184619518 184629019 9502 + 2.204 2.283 0.262

Help

Please Click HERE to learn more details about the results from DEXseq.