ENSG00000116688

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000235329 ENSG00000116688 No_inf pgwt_inf MFN2 protein_coding protein_coding 43.73142 35.67796 50.93611 1.128081 5.39139 0.5135347 14.511382 9.015369 20.611212 0.4682468 1.365468 1.1920714 0.32738333 0.254550 0.418225 0.163675 9.716538e-01 1.010008e-05 FALSE TRUE
ENST00000484391 ENSG00000116688 No_inf pgwt_inf MFN2 protein_coding protein_coding_CDS_not_defined 43.73142 35.67796 50.93611 1.128081 5.39139 0.5135347 2.100088 0.000000 6.300265 0.0000000 6.300265 9.3015568 0.03133333 0.000000 0.094000 0.094000 9.933124e-01 1.010008e-05   FALSE
ENST00000675043 ENSG00000116688 No_inf pgwt_inf MFN2 protein_coding protein_coding_CDS_not_defined 43.73142 35.67796 50.93611 1.128081 5.39139 0.5135347 15.757369 13.804716 16.901282 1.1857362 1.293447 0.2917802 0.36799167 0.386975 0.346600 -0.040375 9.936872e-01 1.010008e-05   FALSE
ENST00000675528 ENSG00000116688 No_inf pgwt_inf MFN2 protein_coding protein_coding_CDS_not_defined 43.73142 35.67796 50.93611 1.128081 5.39139 0.5135347 2.858252 5.494373 0.000000 1.0841735 0.000000 -9.1044343 0.07535000 0.152475 0.000000 -0.152475 1.010008e-05 1.010008e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000116688 E001 0.0000000       1 11980181 11980188 8 +      
ENSG00000116688 E002 0.0000000       1 11980189 11980190 2 +      
ENSG00000116688 E003 0.1308632 0.0122200833 0.4037289783   1 11980191 11980208 18 + 0.000 0.108 9.189
ENSG00000116688 E004 0.1308632 0.0122200833 0.4037289783   1 11980209 11980214 6 + 0.000 0.108 11.234
ENSG00000116688 E005 0.1308632 0.0122200833 0.4037289783   1 11980215 11980215 1 + 0.000 0.108 11.234
ENSG00000116688 E006 0.2448134 0.0163362897 0.8268913498   1 11980216 11980236 21 + 0.084 0.108 0.411
ENSG00000116688 E007 0.2448134 0.0163362897 0.8268913498   1 11980237 11980237 1 + 0.084 0.108 0.411
ENSG00000116688 E008 0.3589885 0.0166698561 0.7734699409   1 11980238 11980258 21 + 0.154 0.108 -0.589
ENSG00000116688 E009 0.4898517 0.0784174720 0.7921714271   1 11980259 11980275 17 + 0.154 0.194 0.411
ENSG00000116688 E010 0.3589885 0.0166698561 0.7734699409   1 11980276 11980280 5 + 0.154 0.108 -0.589
ENSG00000116688 E011 0.5873893 0.0144402017 0.2892347506   1 11980281 11980298 18 + 0.267 0.108 -1.589
ENSG00000116688 E012 1.6821044 0.0645401900 0.5902134269 0.83274950 1 11980299 11980369 71 + 0.464 0.382 -0.438
ENSG00000116688 E013 1.2085211 0.1107295340 0.8456931776 0.94911968 1 11980370 11980370 1 + 0.357 0.328 -0.175
ENSG00000116688 E014 1.6984335 0.0344786898 0.9787971018 0.99722969 1 11980371 11980434 64 + 0.431 0.430 -0.004
ENSG00000116688 E015 0.8314746 0.0905005738 0.4715412595 0.76213644 1 11980435 11980443 9 + 0.314 0.194 -0.911
ENSG00000116688 E016 0.8493305 0.0514073458 0.9999394657 1.00000000 1 11980444 11980445 2 + 0.267 0.266 -0.004
ENSG00000116688 E017 6.2770590 0.0023131589 0.5110397626 0.78727806 1 11980446 11980484 39 + 0.892 0.823 -0.267
ENSG00000116688 E018 0.0000000       1 11981810 11981853 44 +      
ENSG00000116688 E019 0.3608515 0.2568833287 0.8254031152   1 11981854 11981969 116 + 0.154 0.108 -0.590
ENSG00000116688 E020 5.9200909 0.0024799550 0.5523568666 0.81222942 1 11981970 11981973 4 + 0.867 0.804 -0.248
ENSG00000116688 E021 12.8669139 0.0010895282 0.1167462421 0.39529805 1 11981974 11982066 93 + 1.195 1.069 -0.450
ENSG00000116688 E022 9.6804659 0.0014714069 0.5901196549 0.83268013 1 11982067 11982114 48 + 1.049 1.001 -0.174
ENSG00000116688 E023 0.4734391 0.0154649408 0.4731647412   1 11982523 11982590 68 + 0.214 0.108 -1.174
ENSG00000116688 E024 0.0000000       1 11988427 11988516 90 +      
ENSG00000116688 E025 0.2458369 0.0165423485 0.8263755097   1 11988722 11988781 60 + 0.084 0.108 0.411
ENSG00000116688 E026 0.2458369 0.0165423485 0.8263755097   1 11988782 11988843 62 + 0.084 0.108 0.411
ENSG00000116688 E027 22.5756879 0.0006209474 0.2118949445 0.53336439 1 11989165 11989343 179 + 1.405 1.329 -0.265
ENSG00000116688 E028 0.2287699 0.0154486098 0.3550820573   1 11992252 11992278 27 + 0.154 0.000 -12.484
ENSG00000116688 E029 0.9647016 0.0532157517 0.7594332769 0.91464939 1 11992279 11992463 185 + 0.314 0.266 -0.327
ENSG00000116688 E030 0.2462566 0.0165034701 0.8266283344   1 11992464 11992554 91 + 0.084 0.108 0.411
ENSG00000116688 E031 17.0941601 0.0008642865 0.1232903502 0.40671722 1 11992555 11992690 136 + 1.303 1.195 -0.381
ENSG00000116688 E032 0.0000000       1 11996155 11996155 1 +      
ENSG00000116688 E033 18.5834728 0.0039080411 0.2646844682 0.59267081 1 11996156 11996318 163 + 1.326 1.247 -0.276
ENSG00000116688 E034 16.5630305 0.0008457838 0.0010844454 0.01907517 1 11997297 11997421 125 + 1.339 1.099 -0.846
ENSG00000116688 E035 0.9974704 0.0117907189 0.2737032852 0.60199895 1 11998680 11998769 90 + 0.214 0.382 1.148
ENSG00000116688 E036 18.2920626 0.0007852917 0.0883494013 0.34102496 1 11998770 11998878 109 + 1.334 1.218 -0.408
ENSG00000116688 E037 0.7700022 0.0134130512 0.0443574852 0.23133525 1 11998879 11998987 109 + 0.084 0.382 2.733
ENSG00000116688 E038 15.7051863 0.0029602834 0.0335382789 0.19664861 1 11998988 11999095 108 + 1.289 1.128 -0.573
ENSG00000116688 E039 2.5661379 0.0485804535 0.7282119097 0.90083094 1 11999096 11999845 750 + 0.523 0.582 0.273
ENSG00000116688 E040 5.3559465 0.0091540200 0.0276067655 0.17562324 1 12000350 12001400 1051 + 0.664 0.921 1.024
ENSG00000116688 E041 22.4183002 0.0006301656 0.0092661381 0.08847056 1 12001401 12001554 154 + 1.437 1.274 -0.566
ENSG00000116688 E042 8.3315116 0.0020427134 0.0136991957 0.11407616 1 12001769 12001783 15 + 1.065 0.823 -0.911
ENSG00000116688 E043 17.2422671 0.0011397354 0.8586782901 0.95458736 1 12001784 12001836 53 + 1.265 1.254 -0.040
ENSG00000116688 E044 28.4465450 0.0037038080 0.9624666670 0.99115828 1 12001982 12002103 122 + 1.466 1.470 0.014
ENSG00000116688 E045 1.3235828 0.0113586536 0.6589403741 0.86680543 1 12002104 12003462 1359 + 0.396 0.328 -0.397
ENSG00000116688 E046 0.7716647 0.0525466613 0.0503073268 0.24870971 1 12003758 12003889 132 + 0.084 0.382 2.733
ENSG00000116688 E047 30.1715916 0.0096899959 0.6039895671 0.83925127 1 12003992 12004118 127 + 1.508 1.474 -0.117
ENSG00000116688 E048 24.8061935 0.0100666595 0.4639948130 0.75695674 1 12004509 12004613 105 + 1.433 1.383 -0.174
ENSG00000116688 E049 23.0582315 0.0134788136 0.8742846749 0.96044633 1 12004825 12004927 103 + 1.387 1.373 -0.049
ENSG00000116688 E050 43.9547455 0.0037856082 0.5895274323 0.83222771 1 12005711 12005931 221 + 1.638 1.667 0.098
ENSG00000116688 E051 26.7283690 0.0005350918 0.0516142487 0.25253401 1 12006538 12006693 156 + 1.387 1.498 0.384
ENSG00000116688 E052 1.5397190 0.0090067944 0.0043938192 0.05319300 1 12006768 12007052 285 + 0.154 0.582 2.733
ENSG00000116688 E053 30.6503126 0.0227010665 0.4018075775 0.71275227 1 12007053 12007249 197 + 1.469 1.532 0.215
ENSG00000116688 E054 0.0000000       1 12007250 12007295 46 +      
ENSG00000116688 E055 0.3763310 0.0167236049 0.4235901584   1 12009555 12009591 37 + 0.084 0.194 1.411
ENSG00000116688 E056 24.8864865 0.0006344986 0.3769411551 0.69444857 1 12009592 12009726 135 + 1.387 1.440 0.184
ENSG00000116688 E057 412.7578607 0.0001070592 0.0009209098 0.01688101 1 12011496 12013514 2019 + 2.598 2.636 0.126
ENSG00000116688 E058 0.2450383 0.0163431759 0.8268814473   1 12014257 12015211 955 + 0.084 0.108 0.411

Help

Please Click HERE to learn more details about the results from DEXseq.