ENSG00000117676

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374163 ENSG00000117676 No_inf pgwt_inf RPS6KA1 protein_coding nonsense_mediated_decay 189.003 165.0365 200.1403 3.108788 7.347046 0.2782111 41.052439 33.35279 36.95765 2.541899 1.675785 0.14802326 0.21711667 0.20190 0.186125 -0.015775 1.000000e+00 9.426834e-07 FALSE  
ENST00000374168 ENSG00000117676 No_inf pgwt_inf RPS6KA1 protein_coding protein_coding 189.003 165.0365 200.1403 3.108788 7.347046 0.2782111 16.650525 16.40377 17.88436 2.767517 3.036456 0.12459801 0.08869167 0.09910 0.089925 -0.009175 1.000000e+00 9.426834e-07 FALSE  
ENST00000438977 ENSG00000117676 No_inf pgwt_inf RPS6KA1 protein_coding protein_coding 189.003 165.0365 200.1403 3.108788 7.347046 0.2782111 36.180892 43.23848 42.30831 3.746396 8.740362 -0.03136734 0.19343333 0.26125 0.207500 -0.053750 9.928472e-01 9.426834e-07 FALSE  
ENST00000530003 ENSG00000117676 No_inf pgwt_inf RPS6KA1 protein_coding protein_coding 189.003 165.0365 200.1403 3.108788 7.347046 0.2782111 77.748734 63.63251 78.98638 3.438309 3.871742 0.31179574 0.41190000 0.38700 0.397700 0.010700 1.000000e+00 9.426834e-07 FALSE  
ENST00000531382 ENSG00000117676 No_inf pgwt_inf RPS6KA1 protein_coding protein_coding 189.003 165.0365 200.1403 3.108788 7.347046 0.2782111 8.440215 0.00000 15.83375 0.000000 3.327862 10.62969769 0.04107500 0.00000 0.077675 0.077675 9.426834e-07 9.426834e-07 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000117676 E001 0.8846068 1.262140e-02 1.515850e-01 0.4505186700 1 26529761 26529774 14 + 0.158 0.375 1.648
ENSG00000117676 E002 0.8846068 1.262140e-02 1.515850e-01 0.4505186700 1 26529775 26529777 3 + 0.158 0.375 1.648
ENSG00000117676 E003 8.6230020 1.583669e-03 1.588142e-01 0.4612546026 1 26529778 26529983 206 + 0.915 1.047 0.491
ENSG00000117676 E004 0.0000000       1 26530745 26530902 158 +      
ENSG00000117676 E005 0.0000000       1 26531218 26531327 110 +      
ENSG00000117676 E006 0.0000000       1 26531328 26531438 111 +      
ENSG00000117676 E007 6.4764426 2.182362e-02 7.236234e-01 0.8986425262 1 26536925 26536969 45 + 0.853 0.895 0.163
ENSG00000117676 E008 0.8672487 1.621166e-02 5.036520e-01 0.7828891016 1 26543112 26543129 18 + 0.219 0.322 0.741
ENSG00000117676 E009 0.9981119 1.564982e-02 3.103753e-01 0.6366401070 1 26543130 26543161 32 + 0.219 0.375 1.063
ENSG00000117676 E010 1.2265199 5.531860e-02 7.376492e-01 0.9049047470 1 26543162 26543221 60 + 0.321 0.375 0.327
ENSG00000117676 E011 0.3586193 1.662908e-02 7.335696e-01   1 26544075 26544178 104 + 0.158 0.105 -0.674
ENSG00000117676 E012 0.9812020 1.173291e-02 7.518752e-01 0.9110092059 1 26545842 26545844 3 + 0.273 0.322 0.326
ENSG00000117676 E013 1.5878904 8.580730e-03 8.973439e-01 0.9692982949 1 26545845 26545851 7 + 0.403 0.422 0.104
ENSG00000117676 E014 48.0847197 3.184460e-04 1.572708e-01 0.4592594567 1 26545852 26546035 184 + 1.719 1.657 -0.210
ENSG00000117676 E015 37.6879925 3.753238e-04 2.598900e-01 0.5873360054 1 26546867 26546899 33 + 1.613 1.557 -0.189
ENSG00000117676 E016 60.3280877 2.349273e-04 3.484552e-01 0.6692232667 1 26546900 26546983 84 + 1.804 1.768 -0.124
ENSG00000117676 E017 50.9353154 4.348301e-03 6.693746e-03 0.0711115044 1 26547189 26547242 54 + 1.775 1.638 -0.464
ENSG00000117676 E018 42.9671839 6.052924e-04 1.595483e-04 0.0042776682 1 26547243 26547270 28 + 1.719 1.541 -0.608
ENSG00000117676 E019 3.2248726 4.431826e-03 1.784845e-01 0.4905471897 1 26547271 26547590 320 + 0.532 0.709 0.774
ENSG00000117676 E020 58.0446646 2.903972e-04 5.022863e-05 0.0016801747 1 26551397 26551445 49 + 1.842 1.678 -0.554
ENSG00000117676 E021 50.2011760 1.365753e-02 1.991504e-01 0.5170593486 1 26551446 26551477 32 + 1.746 1.665 -0.273
ENSG00000117676 E022 1.3244883 2.404935e-02 6.035777e-01 0.8391568240 1 26551478 26551586 109 + 0.403 0.322 -0.481
ENSG00000117676 E023 78.4155781 2.521044e-03 6.312141e-02 0.2832289759 1 26551644 26551723 80 + 1.934 1.859 -0.251
ENSG00000117676 E024 1.2101185 1.145110e-02 7.843440e-01 0.9251913117 1 26552818 26552896 79 + 0.364 0.322 -0.259
ENSG00000117676 E025 95.0432624 3.812274e-03 4.226291e-02 0.2256657489 1 26553391 26553497 107 + 2.020 1.937 -0.277
ENSG00000117676 E026 0.9820992 2.252312e-01 8.139738e-01 0.9366469605 1 26553498 26554135 638 + 0.273 0.322 0.327
ENSG00000117676 E027 56.8874234 2.603597e-04 2.664616e-01 0.5945935154 1 26554214 26554251 38 + 1.783 1.738 -0.152
ENSG00000117676 E028 0.2626639 1.604605e-02 1.741618e-01   1 26554252 26554447 196 + 0.000 0.190 10.471
ENSG00000117676 E029 119.4548148 1.354602e-04 8.385987e-02 0.3312093676 1 26554596 26554738 143 + 2.103 2.055 -0.162
ENSG00000117676 E030 69.4008310 2.035364e-04 2.502797e-01 0.5771151986 1 26555151 26555183 33 + 1.867 1.825 -0.142
ENSG00000117676 E031 66.8957996 1.961014e-04 7.638933e-01 0.9162766438 1 26555184 26555198 15 + 1.826 1.837 0.036
ENSG00000117676 E032 69.8667943 1.906993e-04 9.614497e-01 0.9907785031 1 26555199 26555221 23 + 1.851 1.849 -0.007
ENSG00000117676 E033 107.8221214 1.371232e-04 5.244909e-01 0.7952972378 1 26555537 26555625 89 + 2.045 2.026 -0.063
ENSG00000117676 E034 0.6048706 1.888504e-02 8.457941e-01   1 26556076 26556163 88 + 0.219 0.190 -0.259
ENSG00000117676 E035 91.7402417 1.622020e-04 4.703016e-01 0.7613574351 1 26556654 26556718 65 + 1.978 1.955 -0.078
ENSG00000117676 E036 86.1457407 3.135447e-03 5.576248e-01 0.8151022421 1 26556998 26557042 45 + 1.951 1.927 -0.079
ENSG00000117676 E037 80.3878682 2.230630e-04 1.030555e-02 0.0945851399 1 26557043 26557100 58 + 1.950 1.862 -0.295
ENSG00000117676 E038 117.4106803 1.241248e-04 4.578562e-01 0.7530363960 1 26558807 26558937 131 + 2.083 2.062 -0.070
ENSG00000117676 E039 136.2959249 1.206529e-04 1.309283e-01 0.4196839282 1 26560726 26560851 126 + 2.118 2.157 0.130
ENSG00000117676 E040 128.2907236 1.399404e-04 9.267625e-01 0.9795348183 1 26561045 26561134 90 + 2.112 2.110 -0.009
ENSG00000117676 E041 193.4261371 9.513899e-05 2.945049e-01 0.6227727830 1 26561505 26561663 159 + 2.278 2.300 0.075
ENSG00000117676 E042 4.8165326 2.978998e-03 2.948032e-04 0.0070242028 1 26571229 26571448 220 + 0.503 0.938 1.812
ENSG00000117676 E043 200.3627151 8.020920e-05 3.320293e-01 0.6556363318 1 26571449 26571610 162 + 2.294 2.314 0.068
ENSG00000117676 E044 126.0087919 1.087944e-03 2.282616e-01 0.5532597162 1 26571849 26571925 77 + 2.120 2.084 -0.122
ENSG00000117676 E045 4.2855030 1.177826e-02 6.336775e-01 0.8540256367 1 26571926 26572175 250 + 0.693 0.753 0.244
ENSG00000117676 E046 162.3328823 1.020647e-04 7.186741e-02 0.3044329234 1 26572176 26572269 94 + 2.233 2.190 -0.144
ENSG00000117676 E047 107.5154221 2.460407e-03 9.788202e-01 0.9972296931 1 26572270 26572293 24 + 2.035 2.035 0.001
ENSG00000117676 E048 229.0896738 2.139061e-03 2.580008e-01 0.5858990143 1 26573224 26573361 138 + 2.347 2.377 0.100
ENSG00000117676 E049 193.5481382 9.952367e-05 3.919871e-02 0.2161976749 1 26574079 26574197 119 + 2.267 2.311 0.148
ENSG00000117676 E050 234.9396887 7.820630e-04 1.765665e-04 0.0046425020 1 26574198 26574376 179 + 2.331 2.414 0.277
ENSG00000117676 E051 579.7005626 3.768698e-05 4.384708e-06 0.0002067199 1 26574377 26575030 654 + 2.737 2.791 0.180

Help

Please Click HERE to learn more details about the results from DEXseq.