ENSG00000118503

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000237289 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding protein_coding 75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 27.254442 15.2939054 29.134439 0.6246685 1.982355 0.9293208 0.35899167 0.347850 0.307125 -0.040725 0.99323661 0.02296223 FALSE TRUE
ENST00000421450 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding protein_coding 75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 9.587079 2.4599782 10.566566 2.4599782 4.632992 2.0983012 0.11590000 0.058450 0.111575 0.053125 0.89220587 0.02296223 FALSE TRUE
ENST00000612899 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding protein_coding 75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 3.509287 3.9412874 6.586575 2.2812621 3.938641 0.7393943 0.05251667 0.088350 0.069200 -0.019150 1.00000000 0.02296223 FALSE TRUE
MSTRG.25389.11 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding   75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 3.408205 0.1036054 7.612911 0.1036054 1.796973 6.0682386 0.03674167 0.002450 0.080325 0.077875 0.02296223 0.02296223 FALSE TRUE
MSTRG.25389.13 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding   75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 3.227472 0.6175666 7.069078 0.6175666 3.417365 3.4957210 0.03737500 0.014675 0.074625 0.059950 0.93306155 0.02296223 FALSE TRUE
MSTRG.25389.14 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding   75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 4.025809 0.5952029 8.289136 0.3125079 1.269329 3.7774703 0.04555000 0.013425 0.087425 0.074000 0.29667742 0.02296223 FALSE TRUE
MSTRG.25389.2 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding   75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 3.949844 3.1931006 3.921511 1.1882681 2.567074 0.2956148 0.05549167 0.071325 0.041125 -0.030200 0.99284725 0.02296223 FALSE TRUE
MSTRG.25389.3 ENSG00000118503 No_inf pgwt_inf TNFAIP3 protein_coding   75.82646 44.0604 94.8938 0.670299 0.2581222 1.106656 15.123594 14.3339288 17.891206 1.2425165 2.935923 0.3196165 0.22015833 0.324525 0.188475 -0.136050 0.96896348 0.02296223 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000118503 E001 0.3767609 1.674133e-02 0.2265157046   6 137867214 137867242 29 + 0.067 0.234 2.094
ENSG00000118503 E002 0.3767609 1.674133e-02 0.2265157046   6 137867243 137867243 1 + 0.067 0.234 2.094
ENSG00000118503 E003 1.0156923 1.166757e-02 0.0141533831 0.116397598 6 137867244 137867258 15 + 0.126 0.498 2.679
ENSG00000118503 E004 0.8840305 1.317475e-02 0.0357189611 0.204704391 6 137867259 137867263 5 + 0.126 0.445 2.416
ENSG00000118503 E005 6.2152342 2.087538e-02 0.0853532452 0.334395747 6 137867264 137867320 57 + 0.755 0.965 0.810
ENSG00000118503 E006 5.7084088 1.416804e-02 0.1661580079 0.472137883 6 137867321 137867321 1 + 0.742 0.911 0.661
ENSG00000118503 E007 20.0388817 7.418331e-04 0.0065111174 0.069828117 6 137867322 137867443 122 + 1.228 1.416 0.654
ENSG00000118503 E008 15.8424296 1.113013e-02 0.1158699418 0.393481877 6 137867444 137867494 51 + 1.153 1.292 0.491
ENSG00000118503 E009 6.4863696 2.326559e-03 0.6471161092 0.861037315 6 137867495 137867518 24 + 0.837 0.892 0.213
ENSG00000118503 E010 4.0336448 3.532079e-03 0.4705573391 0.761484404 6 137867519 137867542 24 + 0.715 0.625 -0.380
ENSG00000118503 E011 0.0000000       6 137867587 137867736 150 +      
ENSG00000118503 E012 0.4907861 1.036805e-01 0.4869414814   6 137870759 137870816 58 + 0.126 0.234 1.094
ENSG00000118503 E013 3.3962599 3.738205e-02 0.1024783816 0.368717228 6 137870817 137870912 96 + 0.701 0.445 -1.169
ENSG00000118503 E014 3.6092348 1.262584e-01 0.0784578360 0.319476312 6 137870913 137871000 88 + 0.742 0.386 -1.662
ENSG00000118503 E015 6.4951234 2.100808e-03 0.0001746596 0.004601478 6 137871001 137871108 108 + 0.972 0.498 -1.965
ENSG00000118503 E016 4.1774384 3.427909e-03 0.0032592970 0.043114836 6 137871109 137871212 104 + 0.804 0.386 -1.906
ENSG00000118503 E017 16.3661436 8.178479e-04 0.1190991086 0.399190647 6 137871213 137871227 15 + 1.257 1.142 -0.408
ENSG00000118503 E018 67.6563697 2.935945e-03 0.1583753835 0.460635306 6 137871228 137871418 191 + 1.836 1.778 -0.194
ENSG00000118503 E019 52.1230236 1.018305e-03 0.3302090946 0.653938670 6 137871419 137871522 104 + 1.718 1.680 -0.130
ENSG00000118503 E020 80.4495692 4.125982e-04 0.3589062363 0.678691143 6 137874845 137875035 191 + 1.900 1.873 -0.090
ENSG00000118503 E021 4.0253561 6.354501e-03 0.1216584783 0.403642374 6 137875036 137875687 652 + 0.604 0.804 0.831
ENSG00000118503 E022 39.1934249 4.413900e-04 0.2364466085 0.561768691 6 137875688 137875835 148 + 1.603 1.548 -0.185
ENSG00000118503 E023 27.4396504 5.264757e-04 0.7552245821 0.912830375 6 137875836 137875995 160 + 1.425 1.450 0.085
ENSG00000118503 E024 75.1474037 2.072916e-04 0.0023678715 0.034297634 6 137875996 137876166 171 + 1.896 1.789 -0.363
ENSG00000118503 E025 76.2486997 3.136623e-03 0.3587424369 0.678550595 6 137877076 137877256 181 + 1.879 1.845 -0.114
ENSG00000118503 E026 349.4935887 6.508721e-05 0.1044215860 0.372458106 6 137878432 137879351 920 + 2.531 2.512 -0.065
ENSG00000118503 E027 3.9921519 2.648792e-02 0.4215024965 0.727426082 6 137879352 137880070 719 + 0.639 0.752 0.473
ENSG00000118503 E028 103.1774561 8.610817e-03 0.9919308908 1.000000000 6 137880071 137880252 182 + 1.994 2.004 0.031
ENSG00000118503 E029 34.1428305 2.829297e-03 0.7927090924 0.928558642 6 137881035 137881036 2 + 1.519 1.539 0.071
ENSG00000118503 E030 912.4496315 7.389370e-04 0.0029012187 0.039879362 6 137881037 137883314 2278 + 2.927 2.963 0.119

Help

Please Click HERE to learn more details about the results from DEXseq.