ENSG00000119714

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000529300 ENSG00000119714 No_inf pgwt_inf GPR68 protein_coding protein_coding_CDS_not_defined 46.46992 10.43495 68.30331 0.7622212 1.935402 2.709361 2.355541 1.3244598 2.729511 0.4749663 1.441629 1.0376626 0.06901667 0.119950 0.038500 -0.081450 0.99284725 0.04304598 FALSE FALSE
ENST00000535815 ENSG00000119714 No_inf pgwt_inf GPR68 protein_coding protein_coding 46.46992 10.43495 68.30331 0.7622212 1.935402 2.709361 1.509241 2.3958969 2.131826 1.0994902 2.131826 -0.1677332 0.08190833 0.214300 0.031425 -0.182875 0.46283833 0.04304598 FALSE TRUE
ENST00000650645 ENSG00000119714 No_inf pgwt_inf GPR68 protein_coding protein_coding 46.46992 10.43495 68.30331 0.7622212 1.935402 2.709361 13.509702 0.1836396 23.914780 0.1836396 3.072808 6.9489881 0.21459167 0.020975 0.351100 0.330125 0.04304598 0.04304598 FALSE TRUE
MSTRG.8978.1 ENSG00000119714 No_inf pgwt_inf GPR68 protein_coding   46.46992 10.43495 68.30331 0.7622212 1.935402 2.709361 14.127404 3.4267587 20.325574 1.3895512 3.060018 2.5648853 0.31892500 0.342000 0.300625 -0.041375 1.00000000 0.04304598 FALSE TRUE
MSTRG.8978.2 ENSG00000119714 No_inf pgwt_inf GPR68 protein_coding   46.46992 10.43495 68.30331 0.7622212 1.935402 2.709361 7.726100 0.8708529 13.149474 0.3408217 1.116214 3.9010568 0.14326667 0.084425 0.192775 0.108350 0.95092873 0.04304598 FALSE TRUE
MSTRG.8978.3 ENSG00000119714 No_inf pgwt_inf GPR68 protein_coding   46.46992 10.43495 68.30331 0.7622212 1.935402 2.709361 5.393230 2.2333409 6.052141 1.3361552 2.801917 1.4341785 0.14367500 0.218325 0.085600 -0.132725 1.00000000 0.04304598 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000119714 E001 0.2454678 1.661599e-02 0.127705925   14 91232460 91232531 72 - 0.038 0.217 2.814
ENSG00000119714 E002 0.5707012 1.469862e-02 1.000000000   14 91232532 91232532 1 - 0.165 0.000 -8.747
ENSG00000119714 E003 298.3452247 7.786619e-05 0.003366469 0.04406123 14 91232533 91234036 1504 - 2.311 2.362 0.169
ENSG00000119714 E004 222.6431328 1.075991e-04 0.017177552 0.13156652 14 91234037 91235117 1081 - 2.200 2.142 -0.195
ENSG00000119714 E005 16.2285948 1.443090e-02 0.581690421 0.82766504 14 91235118 91235179 62 - 1.098 1.031 -0.244
ENSG00000119714 E006 3.6591257 3.880446e-02 0.141549168 0.43498713 14 91237281 91237487 207 - 0.507 0.744 1.036
ENSG00000119714 E007 2.7102582 1.001773e-01 0.253425905 0.58037636 14 91238578 91238746 169 - 0.425 0.628 0.967
ENSG00000119714 E008 13.8300643 1.165670e-03 0.036517698 0.20753436 14 91243109 91243610 502 - 1.055 0.792 -0.993
ENSG00000119714 E009 3.5726254 6.081290e-03 0.273661064 0.60195455 14 91244297 91244434 138 - 0.566 0.361 -1.044
ENSG00000119714 E010 12.1731364 1.135560e-03 0.528265504 0.79780486 14 91244435 91244751 317 - 0.986 0.911 -0.281
ENSG00000119714 E011 0.2456120 1.662740e-02 0.127714993   14 91253715 91253925 211 - 0.038 0.217 2.814

Help

Please Click HERE to learn more details about the results from DEXseq.