ENSG00000119950

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000239007 ENSG00000119950 No_inf pgwt_inf MXI1 protein_coding protein_coding 4.039024 3.744807 4.350038 0.5811456 0.5832624 0.2156018 1.5043002 1.6444980 0.6710002 0.64654387 0.4079290 -1.28066648 0.4062167 0.515025 0.128425 -0.386600 0.992847247 0.005386696 FALSE TRUE
ENST00000332674 ENSG00000119950 No_inf pgwt_inf MXI1 protein_coding protein_coding 4.039024 3.744807 4.350038 0.5811456 0.5832624 0.2156018 1.1558362 1.3109005 1.2947893 0.63877098 0.2732277 -0.01770499 0.2824167 0.316325 0.336300 0.019975 1.000000000 0.005386696 FALSE TRUE
ENST00000369612 ENSG00000119950 No_inf pgwt_inf MXI1 protein_coding protein_coding 4.039024 3.744807 4.350038 0.5811456 0.5832624 0.2156018 0.1455095 0.4365285 0.0000000 0.43652849 0.0000000 -5.48068032 0.0288000 0.086400 0.000000 -0.086400 0.992847247 0.005386696 FALSE TRUE
ENST00000650952 ENSG00000119950 No_inf pgwt_inf MXI1 protein_coding protein_coding 4.039024 3.744807 4.350038 0.5811456 0.5832624 0.2156018 0.7770090 0.0000000 2.0275744 0.00000000 0.5804247 7.67070896 0.1774750 0.000000 0.441725 0.441725 0.005386696 0.005386696 FALSE TRUE
ENST00000652323 ENSG00000119950 No_inf pgwt_inf MXI1 protein_coding nonsense_mediated_decay 4.039024 3.744807 4.350038 0.5811456 0.5832624 0.2156018 0.2066890 0.1862589 0.3566740 0.08096422 0.1773366 0.90173964 0.0512000 0.043725 0.093575 0.049850 0.992914090 0.005386696   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000119950 E001 0.1316618 0.0124340283 0.558949263   10 110207605 110207683 79 + 0.000 0.094 9.489
ENSG00000119950 E002 0.9638715 0.3513795676 0.640424288 0.8577733 10 110207684 110208082 399 + 0.351 0.237 -0.778
ENSG00000119950 E003 0.0000000       10 110210231 110210315 85 +      
ENSG00000119950 E004 0.2628107 0.0164829578 0.257192462   10 110225993 110226034 42 + 0.000 0.171 12.259
ENSG00000119950 E005 0.5090673 0.0190023696 0.342653101   10 110226035 110226083 49 + 0.096 0.236 1.543
ENSG00000119950 E006 0.6241751 0.4926447186 0.856001338   10 110226084 110226190 107 + 0.175 0.237 0.543
ENSG00000119950 E007 0.2462566 0.0163371312 0.973268691   10 110226191 110226203 13 + 0.096 0.094 -0.042
ENSG00000119950 E008 0.7551235 0.0423477762 0.446791945 0.7453600 10 110226204 110226283 80 + 0.175 0.293 0.958
ENSG00000119950 E009 0.0000000       10 110226284 110226350 67 +      
ENSG00000119950 E010 0.0000000       10 110226351 110226386 36 +      
ENSG00000119950 E011 0.0000000       10 110226590 110226626 37 +      
ENSG00000119950 E012 0.0000000       10 110226777 110226796 20 +      
ENSG00000119950 E013 0.0000000       10 110226805 110226810 6 +      
ENSG00000119950 E014 0.0000000       10 110226811 110226816 6 +      
ENSG00000119950 E015 0.0000000       10 110226817 110226818 2 +      
ENSG00000119950 E016 0.0000000       10 110226819 110226830 12 +      
ENSG00000119950 E017 0.0000000       10 110226831 110226834 4 +      
ENSG00000119950 E018 0.0000000       10 110226835 110226850 16 +      
ENSG00000119950 E019 0.0000000       10 110226851 110226852 2 +      
ENSG00000119950 E020 0.0000000       10 110226853 110226854 2 +      
ENSG00000119950 E021 0.0000000       10 110226855 110226874 20 +      
ENSG00000119950 E022 0.0000000       10 110226875 110226885 11 +      
ENSG00000119950 E023 0.0000000       10 110226995 110227014 20 +      
ENSG00000119950 E024 0.0000000       10 110227074 110227086 13 +      
ENSG00000119950 E025 0.0000000       10 110227087 110227100 14 +      
ENSG00000119950 E026 0.0000000       10 110227101 110227118 18 +      
ENSG00000119950 E027 0.0000000       10 110227125 110227136 12 +      
ENSG00000119950 E028 0.0000000       10 110227137 110227142 6 +      
ENSG00000119950 E029 0.0000000       10 110227143 110227162 20 +      
ENSG00000119950 E030 0.0000000       10 110227179 110227182 4 +      
ENSG00000119950 E031 0.0000000       10 110227183 110227202 20 +      
ENSG00000119950 E032 0.0000000       10 110227203 110227213 11 +      
ENSG00000119950 E033 0.0000000       10 110227306 110227317 12 +      
ENSG00000119950 E034 0.0000000       10 110227318 110227325 8 +      
ENSG00000119950 E035 0.0000000       10 110227326 110227337 12 +      
ENSG00000119950 E036 0.0000000       10 110227338 110227339 2 +      
ENSG00000119950 E037 0.0000000       10 110227340 110227345 6 +      
ENSG00000119950 E038 0.0000000       10 110227346 110227354 9 +      
ENSG00000119950 E039 0.0000000       10 110227355 110227365 11 +      
ENSG00000119950 E040 0.0000000       10 110227366 110227377 12 +      
ENSG00000119950 E041 0.0000000       10 110227378 110227386 9 +      
ENSG00000119950 E042 0.0000000       10 110227387 110227398 12 +      
ENSG00000119950 E043 0.0000000       10 110227399 110227406 8 +      
ENSG00000119950 E044 0.1311489 0.0128638264 0.558422324   10 110227413 110227431 19 + 0.000 0.094 11.398
ENSG00000119950 E045 0.1311489 0.0128638264 0.558422324   10 110227478 110227501 24 + 0.000 0.094 11.398
ENSG00000119950 E046 0.0000000       10 110227510 110227540 31 +      
ENSG00000119950 E047 0.0000000       10 110227541 110227542 2 +      
ENSG00000119950 E048 0.0000000       10 110227543 110227642 100 +      
ENSG00000119950 E049 0.0000000       10 110227643 110227678 36 +      
ENSG00000119950 E050 0.1308632 0.0123471925 0.559014505   10 110227679 110227785 107 + 0.000 0.094 11.398
ENSG00000119950 E051 0.3594082 0.0169029885 0.557790477   10 110227786 110227882 97 + 0.175 0.094 -1.042
ENSG00000119950 E052 0.9645699 0.0129164486 0.438706139 0.7399490 10 110227883 110228188 306 + 0.351 0.236 -0.779
ENSG00000119950 E053 1.4888500 0.0944630848 0.628049825 0.8509444 10 110228189 110228202 14 + 0.351 0.430 0.443
ENSG00000119950 E054 3.1888326 0.0068335941 0.898888846 0.9697225 10 110228203 110228321 119 + 0.626 0.617 -0.042
ENSG00000119950 E055 1.2086779 0.0318314711 0.475987333 0.7653722 10 110244828 110244828 1 + 0.396 0.293 -0.627
ENSG00000119950 E056 1.9444147 0.0081887000 0.548541331 0.8102130 10 110244829 110244857 29 + 0.510 0.430 -0.405
ENSG00000119950 E057 0.0000000       10 110244858 110244873 16 +      
ENSG00000119950 E058 0.0000000       10 110245743 110245818 76 +      
ENSG00000119950 E059 0.0000000       10 110260999 110261145 147 +      
ENSG00000119950 E060 0.0000000       10 110270208 110270571 364 +      
ENSG00000119950 E061 3.5311728 0.0054512545 0.486176402 0.7721052 10 110279180 110279294 115 + 0.697 0.617 -0.342
ENSG00000119950 E062 0.0000000       10 110279490 110279683 194 +      
ENSG00000119950 E063 6.0858865 0.0025134115 0.295931364 0.6237765 10 110279914 110280085 172 + 0.901 0.800 -0.390
ENSG00000119950 E064 0.0000000       10 110280086 110280147 62 +      
ENSG00000119950 E065 8.8168374 0.0017280492 0.020369709 0.1457727 10 110284824 110285146 323 + 1.086 0.890 -0.727
ENSG00000119950 E066 13.2375493 0.0010518101 0.632216450 0.8532420 10 110285147 110285641 495 + 1.166 1.139 -0.096
ENSG00000119950 E067 23.7559333 0.0006794838 0.003915511 0.0489425 10 110285642 110287365 1724 + 1.304 1.455 0.524

Help

Please Click HERE to learn more details about the results from DEXseq.