ENSG00000120519

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000335472 ENSG00000120519 No_inf pgwt_inf SLC10A7 protein_coding protein_coding 7.250669 2.589602 3.894334 0.2599956 0.2722259 0.5867858 1.19031028 0.2818961 2.62810322 0.2818961 0.88160875 3.1759743 0.33955000 0.127225 0.659050 0.531825 0.59489496 0.01453535 FALSE TRUE
ENST00000432059 ENSG00000120519 No_inf pgwt_inf SLC10A7 protein_coding protein_coding 7.250669 2.589602 3.894334 0.2599956 0.2722259 0.5867858 1.19070458 0.6008004 0.77937790 0.3484192 0.77937790 0.3700151 0.24975000 0.238500 0.222675 -0.015825 0.99284725 0.01453535 FALSE TRUE
ENST00000511315 ENSG00000120519 No_inf pgwt_inf SLC10A7 protein_coding retained_intron 7.250669 2.589602 3.894334 0.2599956 0.2722259 0.5867858 0.50768022 1.2344333 0.09410161 0.2106608 0.03138888 -3.5794246 0.16602500 0.467650 0.023500 -0.444150 0.01453535 0.01453535 FALSE TRUE
ENST00000693222 ENSG00000120519 No_inf pgwt_inf SLC10A7 protein_coding protein_coding 7.250669 2.589602 3.894334 0.2599956 0.2722259 0.5867858 0.09065991 0.2719797 0.00000000 0.2719797 0.00000000 -4.8175196 0.03231667 0.096950 0.000000 -0.096950 0.99284725 0.01453535 FALSE TRUE
MSTRG.22391.5 ENSG00000120519 No_inf pgwt_inf SLC10A7 protein_coding   7.250669 2.589602 3.894334 0.2599956 0.2722259 0.5867858 4.02684806 0.0000000 0.00000000 0.0000000 0.00000000 0.0000000 0.14530833 0.000000 0.000000 0.000000   0.01453535   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000120519 E001 0.3587608 0.085368218 1.000000e+00   4 146253975 146253980 6 - 0.131 0.127 -0.045
ENSG00000120519 E002 0.9462916 0.017840456 5.077008e-01 7.853776e-01 4 146253981 146254121 141 - 0.313 0.226 -0.630
ENSG00000120519 E003 38.0612097 0.000838477 4.538780e-15 9.448850e-13 4 146254122 146256490 2369 - 1.658 1.395 -0.899
ENSG00000120519 E004 1.5180015 0.012234147 9.977728e-02 3.643151e-01 4 146256491 146256520 30 - 0.468 0.226 -1.505
ENSG00000120519 E005 0.5698317 0.016669032 8.526032e-02   4 146256826 146256918 93 - 0.274 0.000 -12.575
ENSG00000120519 E006 0.2279811 0.015673708 5.066958e-01   4 146256919 146256936 18 - 0.131 0.000 -11.566
ENSG00000120519 E007 2.8423784 0.005962225 2.423028e-01 5.686258e-01 4 146258692 146258837 146 - 0.620 0.484 -0.630
ENSG00000120519 E008 1.7004932 0.008998390 6.038321e-01 8.392441e-01 4 146283192 146283265 74 - 0.381 0.484 0.539
ENSG00000120519 E009 0.0000000       4 146289102 146289141 40 -      
ENSG00000120519 E010 1.7700100 0.032120447 9.707785e-03 9.107392e-02 4 146292929 146292980 52 - 0.231 0.644 2.277
ENSG00000120519 E011 3.9208424 0.004190969 4.666080e-13 7.765001e-11 4 146293391 146293929 539 - 0.070 1.037 5.812
ENSG00000120519 E012 3.1114088 0.005165624 1.449763e-02 1.179676e-01 4 146293930 146294095 166 - 0.441 0.786 1.539
ENSG00000120519 E013 1.1297809 0.012589019 6.386116e-02 2.850305e-01 4 146294096 146294168 73 - 0.184 0.484 1.955
ENSG00000120519 E014 2.2602149 0.006352039 8.328880e-03 8.236716e-02 4 146305926 146306009 84 - 0.313 0.707 1.955
ENSG00000120519 E015 1.8488297 0.008423657 1.743971e-01 4.842327e-01 4 146325961 146325996 36 - 0.349 0.571 1.147
ENSG00000120519 E016 0.5257018 0.016657357 1.015541e-02   4 146407298 146408606 1309 - 0.000 0.374 13.376
ENSG00000120519 E017 0.0000000       4 146408761 146412149 3389 -      
ENSG00000120519 E018 0.5254081 0.221214282 2.343075e-02   4 146441666 146442324 659 - 0.000 0.374 13.198
ENSG00000120519 E019 0.0000000       4 146442325 146442782 458 -      
ENSG00000120519 E020 1.0778971 0.019164069 8.672520e-01 9.578474e-01 4 146442783 146442821 39 - 0.313 0.306 -0.045
ENSG00000120519 E021 0.0000000       4 146477879 146478301 423 -      
ENSG00000120519 E022 1.4198068 0.010893235 4.161197e-01 7.232232e-01 4 146503849 146503903 55 - 0.412 0.306 -0.630
ENSG00000120519 E023 0.9467266 0.015232468 5.080587e-01 7.855709e-01 4 146503904 146503924 21 - 0.313 0.226 -0.630
ENSG00000120519 E024 0.0000000       4 146509172 146509261 90 -      
ENSG00000120519 E025 2.9265593 0.031422465 3.495063e-01 6.701262e-01 4 146509913 146510049 137 - 0.517 0.677 0.713
ENSG00000120519 E026 0.3594082 0.017158657 1.000000e+00   4 146513902 146515151 1250 - 0.131 0.127 -0.046
ENSG00000120519 E027 2.2080184 0.006581618 2.266361e-01 5.510695e-01 4 146517038 146517120 83 - 0.412 0.609 0.955
ENSG00000120519 E028 2.7669089 0.005378711 2.115573e-03 3.167155e-02 4 146521618 146522372 755 - 0.349 0.786 2.054

Help

Please Click HERE to learn more details about the results from DEXseq.