ENSG00000120705

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360541 ENSG00000120705 No_inf pgwt_inf ETF1 protein_coding protein_coding 69.21365 42.92152 79.95485 1.543371 1.134704 0.8973286 59.577898 38.215679 67.1950117 0.933506 2.9649415 0.8140267 0.86806667 0.89275 0.840900 -0.051850 9.928472e-01 9.474692e-05 FALSE TRUE
ENST00000503014 ENSG00000120705 No_inf pgwt_inf ETF1 protein_coding protein_coding 69.21365 42.92152 79.95485 1.543371 1.134704 0.8973286 5.121425 0.000000 9.1557200 0.000000 1.7732684 9.8401044 0.06090833 0.00000 0.114125 0.114125 9.474692e-05 9.474692e-05 FALSE TRUE
ENST00000503183 ENSG00000120705 No_inf pgwt_inf ETF1 protein_coding retained_intron 69.21365 42.92152 79.95485 1.543371 1.134704 0.8973286 1.570547 2.684854 0.2819347 1.188365 0.2819347 -3.2064895 0.02755833 0.05985 0.003550 -0.056300 5.412269e-01 9.474692e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000120705 E001 480.3413100 6.084328e-05 8.972833e-06 0.000386947 5 138506095 138507989 1895 - 2.650 2.701 0.170
ENSG00000120705 E002 192.7451772 9.323339e-05 9.857643e-01 0.999375210 5 138507990 138508387 398 - 2.275 2.274 -0.002
ENSG00000120705 E003 79.0500400 1.881472e-04 9.272408e-01 0.979708763 5 138508669 138508816 148 - 1.890 1.892 0.010
ENSG00000120705 E004 34.2386514 4.103013e-04 4.175742e-01 0.724141099 5 138510565 138510629 65 - 1.551 1.507 -0.148
ENSG00000120705 E005 52.6991414 3.272513e-04 8.628202e-01 0.956115624 5 138511045 138511103 59 - 1.720 1.713 -0.026
ENSG00000120705 E006 76.7122621 6.858869e-04 1.261158e-01 0.411720290 5 138511104 138511200 97 - 1.856 1.911 0.183
ENSG00000120705 E007 3.0751503 4.972446e-03 8.245409e-02 0.328302698 5 138511201 138511474 274 - 0.498 0.729 1.021
ENSG00000120705 E008 45.5198916 7.312690e-04 9.868008e-01 0.999700489 5 138511475 138511524 50 - 1.655 1.655 0.002
ENSG00000120705 E009 52.9035507 9.273593e-04 7.388177e-02 0.308679966 5 138511525 138511604 80 - 1.748 1.668 -0.269
ENSG00000120705 E010 1.9197219 1.553673e-02 4.764777e-04 0.010195202 5 138512699 138512763 65 - 0.187 0.701 2.906
ENSG00000120705 E011 30.7323339 1.878347e-02 3.824805e-01 0.698752654 5 138512764 138512771 8 - 1.512 1.449 -0.214
ENSG00000120705 E012 78.8795102 1.983782e-04 4.570341e-01 0.752809516 5 138512772 138512954 183 - 1.900 1.873 -0.088
ENSG00000120705 E013 29.0154723 4.888914e-04 1.959614e-01 0.512731307 5 138513568 138513650 83 - 1.492 1.417 -0.258
ENSG00000120705 E014 21.5204019 6.335857e-04 3.781399e-01 0.695497273 5 138513651 138513706 56 - 1.362 1.303 -0.204
ENSG00000120705 E015 53.0042870 3.631420e-04 6.250873e-02 0.281573075 5 138517561 138517700 140 - 1.749 1.668 -0.274
ENSG00000120705 E016 61.0990097 7.146207e-04 6.329421e-03 0.068348991 5 138518692 138518867 176 - 1.820 1.707 -0.383
ENSG00000120705 E017 0.4746574 3.280123e-02 7.120735e-01   5 138529555 138529678 124 - 0.187 0.126 -0.679
ENSG00000120705 E018 0.0000000       5 138541519 138541711 193 -      
ENSG00000120705 E019 0.1141751 1.119959e-02 1.000000e+00   5 138542634 138542704 71 - 0.071 0.000 -8.272
ENSG00000120705 E020 1.0633333 2.089637e-01 5.657360e-01 0.818846088 5 138542705 138542832 128 - 0.353 0.223 -0.903
ENSG00000120705 E021 30.1250677 4.990947e-04 2.607937e-03 0.036849860 5 138542833 138542936 104 - 1.539 1.364 -0.605
ENSG00000120705 E022 10.1778287 1.587117e-03 3.973522e-02 0.217776562 5 138543097 138543236 140 - 1.101 0.905 -0.724

Help

Please Click HERE to learn more details about the results from DEXseq.