ENSG00000122515

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000463056 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding retained_intron 56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 1.889259 0.000000 4.231759 0.0000000 2.4503580 8.72851901 0.03465833 0.000000 0.078925 0.078925 9.828653e-01 3.911931e-05 FALSE TRUE
ENST00000478045 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding retained_intron 56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 6.809724 8.413372 7.113569 1.0808016 0.3943467 -0.24179756 0.12346667 0.153425 0.125800 -0.027625 9.932366e-01 3.911931e-05 FALSE TRUE
ENST00000482322 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding retained_intron 56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 1.827714 5.483142 0.000000 0.6114017 0.0000000 -9.10148766 0.03375000 0.101250 0.000000 -0.101250 3.911931e-05 3.911931e-05 FALSE FALSE
ENST00000492558 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding protein_coding_CDS_not_defined 56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 12.559276 12.642684 5.933006 7.6944156 5.9330058 -1.09017871 0.19370833 0.186725 0.085850 -0.100875 9.928472e-01 3.911931e-05   FALSE
MSTRG.26153.14 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding   56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 3.115422 4.657158 3.937991 2.0988924 2.2746933 -0.24142557 0.05475000 0.084625 0.067625 -0.017000 9.928472e-01 3.911931e-05 FALSE TRUE
MSTRG.26153.2 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding   56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 1.189702 3.569105 0.000000 0.3083688 0.0000000 -8.48345495 0.02158333 0.064750 0.000000 -0.064750 2.061449e-04 3.911931e-05 TRUE TRUE
MSTRG.26153.25 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding   56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 3.208577 3.533254 3.474161 0.3693001 0.2519259 -0.02426378 0.05867500 0.064250 0.062050 -0.002200 1.000000e+00 3.911931e-05 TRUE TRUE
MSTRG.26153.4 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding   56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 3.312695 2.534420 5.411014 0.8998973 0.5371339 1.09122567 0.06004167 0.051850 0.095050 0.043200 9.928472e-01 3.911931e-05 TRUE TRUE
MSTRG.26153.8 ENSG00000122515 No_inf pgwt_inf ZMIZ2 protein_coding   56.68839 56.37168 57.0152 6.764112 4.445182 0.01637316 8.151426 3.343645 9.901361 1.3574552 0.6601531 1.56335331 0.14806667 0.062600 0.178400 0.115800 9.486228e-01 3.911931e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000122515 E001 0.1145948 1.122558e-02 6.482458e-01   7 44748555 44748563 9 + 0.087 0.000 -10.161
ENSG00000122515 E002 0.5090673 2.806155e-02 2.399736e-01   7 44748564 44748568 5 + 0.087 0.257 1.862
ENSG00000122515 E003 0.6405823 1.503304e-02 1.172054e-01 0.396174025 7 44748569 44748571 3 + 0.087 0.318 2.277
ENSG00000122515 E004 1.6035111 8.202256e-03 5.420955e-01 0.806249089 7 44748572 44748580 9 + 0.368 0.460 0.500
ENSG00000122515 E005 3.2872142 4.661275e-03 9.297227e-01 0.980371822 7 44748581 44748631 51 + 0.637 0.627 -0.045
ENSG00000122515 E006 0.0000000       7 44748847 44748857 11 +      
ENSG00000122515 E007 0.0000000       7 44748858 44748861 4 +      
ENSG00000122515 E008 0.0000000       7 44748862 44748865 4 +      
ENSG00000122515 E009 0.2276119 2.760185e-01 3.794998e-01   7 44748866 44748870 5 + 0.160 0.000 -12.685
ENSG00000122515 E010 0.3415621 2.993478e-02 1.472668e-01   7 44748871 44748880 10 + 0.222 0.000 -14.032
ENSG00000122515 E011 0.4724253 3.042675e-02 4.221951e-01   7 44748881 44748895 15 + 0.222 0.104 -1.308
ENSG00000122515 E012 0.8493179 1.762162e-02 8.988167e-01 0.969722453 7 44748896 44748902 7 + 0.276 0.257 -0.138
ENSG00000122515 E013 1.2092337 1.677266e-02 7.411840e-01 0.906541048 7 44748903 44748908 6 + 0.368 0.318 -0.308
ENSG00000122515 E014 3.6403829 4.280536e-03 2.760312e-03 0.038399871 7 44748909 44748961 53 + 0.817 0.418 -1.782
ENSG00000122515 E015 4.9204948 1.043518e-02 1.651496e-01 0.470617473 7 44748962 44748991 30 + 0.845 0.679 -0.670
ENSG00000122515 E016 0.4564454 1.865321e-01 1.047864e-01   7 44749815 44749980 166 + 0.276 0.000 -13.817
ENSG00000122515 E017 0.2450991 1.640971e-02 8.831351e-01   7 44750972 44751091 120 + 0.087 0.104 0.277
ENSG00000122515 E018 0.0000000       7 44756179 44756187 9 +      
ENSG00000122515 E019 8.7151987 3.871157e-03 4.029121e-01 0.713488315 7 44756188 44756204 17 + 1.024 0.945 -0.291
ENSG00000122515 E020 15.4629042 9.136240e-04 1.577131e-01 0.459744438 7 44756205 44756299 95 + 1.264 1.161 -0.364
ENSG00000122515 E021 24.1534267 5.685800e-04 5.321131e-02 0.257429636 7 44756425 44756539 115 + 1.453 1.338 -0.398
ENSG00000122515 E022 8.7367410 1.696550e-03 2.555135e-01 0.582629067 7 44756540 44756946 407 + 0.933 1.040 0.399
ENSG00000122515 E023 11.0853529 1.242674e-03 1.085086e-01 0.380217048 7 44756947 44756974 28 + 1.143 1.007 -0.493
ENSG00000122515 E024 14.1936965 9.565384e-04 4.609463e-01 0.754853380 7 44756975 44757042 68 + 1.207 1.153 -0.195
ENSG00000122515 E025 19.2932232 7.760490e-04 4.783310e-02 0.241214774 7 44757043 44757149 107 + 1.366 1.235 -0.460
ENSG00000122515 E026 0.5871644 1.511330e-02 2.467679e-01   7 44757150 44757175 26 + 0.276 0.104 -1.723
ENSG00000122515 E027 3.3884180 2.647290e-02 3.973007e-02 0.217776562 7 44757176 44757377 202 + 0.477 0.767 1.277
ENSG00000122515 E028 30.3892189 4.593141e-03 5.572648e-01 0.814986980 7 44757378 44757561 184 + 1.513 1.479 -0.118
ENSG00000122515 E029 48.6854346 1.993605e-03 8.327958e-01 0.943761780 7 44757848 44758108 261 + 1.691 1.702 0.038
ENSG00000122515 E030 4.9576557 2.906279e-03 1.266977e-01 0.412494774 7 44759181 44759280 100 + 0.679 0.857 0.713
ENSG00000122515 E031 37.3557469 3.885955e-04 4.708510e-02 0.239329701 7 44759281 44759460 180 + 1.533 1.631 0.334
ENSG00000122515 E032 8.8815841 1.558105e-03 8.044496e-01 0.933075725 7 44759461 44759659 199 + 1.005 0.983 -0.080
ENSG00000122515 E033 3.4972128 1.138147e-02 4.406168e-01 0.741038747 7 44759660 44759686 27 + 0.699 0.598 -0.433
ENSG00000122515 E034 6.4324697 2.249096e-03 1.350860e-01 0.426013941 7 44759687 44759733 47 + 0.786 0.945 0.612
ENSG00000122515 E035 20.7473203 1.510498e-03 7.003120e-04 0.013662904 7 44759734 44759950 217 + 1.213 1.438 0.784
ENSG00000122515 E036 25.9825650 5.324925e-04 3.414842e-02 0.199040129 7 44759951 44760150 200 + 1.366 1.490 0.428
ENSG00000122515 E037 20.1023668 1.886482e-02 8.997161e-02 0.344282640 7 44760151 44760228 78 + 1.247 1.393 0.508
ENSG00000122515 E038 25.6493268 5.706548e-04 7.901864e-04 0.014981370 7 44760229 44760424 196 + 1.318 1.516 0.684
ENSG00000122515 E039 52.9205309 2.681290e-04 5.584840e-01 0.815419040 7 44760425 44760593 169 + 1.742 1.720 -0.076
ENSG00000122515 E040 47.8036766 2.900951e-04 1.176876e-01 0.397028580 7 44761449 44761593 145 + 1.654 1.722 0.233
ENSG00000122515 E041 8.9874267 3.812363e-03 4.450395e-03 0.053608106 7 44761594 44761694 101 + 0.845 1.118 1.014
ENSG00000122515 E042 44.9570482 3.335153e-04 1.810146e-01 0.493825100 7 44761695 44761807 113 + 1.632 1.692 0.207
ENSG00000122515 E043 38.2335352 3.814374e-04 8.004337e-01 0.931511414 7 44761808 44761905 98 + 1.599 1.588 -0.036
ENSG00000122515 E044 38.7694246 4.036500e-03 5.228654e-01 0.794368706 7 44762881 44762986 106 + 1.615 1.582 -0.114
ENSG00000122515 E045 52.4515431 3.038954e-04 6.109080e-01 0.843033599 7 44763256 44763413 158 + 1.737 1.718 -0.066
ENSG00000122515 E046 0.1311489 1.232835e-02 4.449686e-01   7 44763689 44763750 62 + 0.000 0.104 12.237
ENSG00000122515 E047 34.2841787 6.840118e-03 8.441963e-01 0.948576223 7 44764419 44764486 68 + 1.542 1.553 0.041
ENSG00000122515 E048 41.8153150 6.357873e-03 9.707181e-01 0.994511014 7 44764941 44765009 69 + 1.632 1.631 -0.001
ENSG00000122515 E049 85.5352853 6.256841e-03 5.371020e-01 0.803216925 7 44765335 44765579 245 + 1.949 1.924 -0.082
ENSG00000122515 E050 10.2294766 4.350617e-02 2.714170e-01 0.599502601 7 44765580 44765710 131 + 0.986 1.109 0.451
ENSG00000122515 E051 5.7064050 4.568647e-02 8.178097e-01 0.937510422 7 44765711 44765743 33 + 0.845 0.806 -0.155
ENSG00000122515 E052 15.4642881 1.515456e-03 1.842626e-02 0.137517846 7 44765744 44765966 223 + 1.122 1.298 0.625
ENSG00000122515 E053 16.5501802 7.916072e-04 6.474636e-04 0.012839466 7 44765967 44766056 90 + 1.107 1.353 0.871
ENSG00000122515 E054 8.2395841 4.895142e-02 3.856588e-02 0.214153598 7 44766057 44766163 107 + 0.817 1.081 0.991
ENSG00000122515 E055 22.7473096 6.141250e-04 1.370013e-01 0.428747936 7 44766164 44766221 58 + 1.417 1.327 -0.314
ENSG00000122515 E056 40.3896221 2.222976e-03 5.751765e-01 0.824565843 7 44766222 44766333 112 + 1.629 1.603 -0.090
ENSG00000122515 E057 75.1570931 1.617112e-02 4.169816e-01 0.723823029 7 44766421 44766663 243 + 1.856 1.907 0.175
ENSG00000122515 E058 341.7559422 9.310151e-05 3.560124e-05 0.001254932 7 44767516 44769114 1599 + 2.563 2.503 -0.197
ENSG00000122515 E059 7.5163821 4.223195e-03 1.686750e-02 0.129979408 7 44769115 44769224 110 + 1.033 0.787 -0.934
ENSG00000122515 E060 10.7717828 4.836493e-03 3.776127e-01 0.694995668 7 44769225 44769454 230 + 1.107 1.029 -0.281
ENSG00000122515 E061 41.1592542 3.479005e-04 6.347575e-01 0.854511058 7 44769455 44770313 859 + 1.613 1.637 0.080

Help

Please Click HERE to learn more details about the results from DEXseq.