ENSG00000123933

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337190 ENSG00000123933 No_inf pgwt_inf MXD4 protein_coding protein_coding 39.78258 32.35541 47.11465 1.642323 4.648272 0.5420288 16.020652 22.6037944 11.886274 0.9474874 0.9590020 -0.92669334 0.43930833 0.705300 0.254125 -0.451175 0.04633694 0.04633694 FALSE TRUE
ENST00000513380 ENSG00000123933 No_inf pgwt_inf MXD4 protein_coding nonsense_mediated_decay 39.78258 32.35541 47.11465 1.642323 4.648272 0.5420288 4.427993 0.8161984 6.551602 0.8161984 1.5537086 2.98948785 0.10623333 0.025625 0.143525 0.117900 0.31319543 0.04633694   FALSE
ENST00000515378 ENSG00000123933 No_inf pgwt_inf MXD4 protein_coding protein_coding_CDS_not_defined 39.78258 32.35541 47.11465 1.642323 4.648272 0.5420288 6.242561 1.2330662 11.194465 0.7122214 2.1895487 3.17209873 0.13890833 0.035600 0.231950 0.196350 0.38362225 0.04633694 FALSE FALSE
ENST00000537353 ENSG00000123933 No_inf pgwt_inf MXD4 protein_coding miRNA 39.78258 32.35541 47.11465 1.642323 4.648272 0.5420288 6.773648 1.1738407 11.545664 1.1738407 4.2820942 3.28705332 0.14731667 0.032475 0.223400 0.190925 0.67905394 0.04633694 FALSE FALSE
MSTRG.21446.2 ENSG00000123933 No_inf pgwt_inf MXD4 protein_coding   39.78258 32.35541 47.11465 1.642323 4.648272 0.5420288 2.380744 1.0649290 1.947638 0.6718199 1.9476375 0.86487230 0.06194167 0.032075 0.058250 0.026175 0.99284725 0.04633694 TRUE TRUE
MSTRG.21446.3 ENSG00000123933 No_inf pgwt_inf MXD4 protein_coding   39.78258 32.35541 47.11465 1.642323 4.648272 0.5420288 3.174832 3.7751925 3.989003 1.2687841 0.2764952 0.07927378 0.08404167 0.116850 0.088700 -0.028150 1.00000000 0.04633694 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000123933 E001 0.1315150 0.0122986413 7.419598e-01   4 2247432 2247438 7 - 0.000 0.082 8.341
ENSG00000123933 E002 64.0544686 0.0002366896 1.567173e-08 1.310157e-06 4 2247439 2248116 678 - 1.657 1.873 0.728
ENSG00000123933 E003 13.2409410 0.0013051435 1.496348e-02 1.203496e-01 4 2248117 2248196 80 - 1.010 1.209 0.717
ENSG00000123933 E004 119.0890353 0.0002875597 1.366742e-14 2.699875e-12 4 2248197 2249463 1267 - 1.928 2.137 0.703
ENSG00000123933 E005 44.0491779 0.0003584101 4.959566e-05 1.660047e-03 4 2249464 2250076 613 - 1.519 1.705 0.634
ENSG00000123933 E006 117.0392150 0.0007872218 2.090287e-05 7.994692e-04 4 2250077 2250657 581 - 2.130 2.010 -0.400
ENSG00000123933 E007 38.2716382 0.0102380141 1.102846e-01 3.834499e-01 4 2250658 2250701 44 - 1.643 1.540 -0.352
ENSG00000123933 E008 57.1423665 0.0004972033 1.807450e-02 1.357867e-01 4 2251084 2251246 163 - 1.809 1.714 -0.323
ENSG00000123933 E009 45.2704777 0.0003884691 1.747374e-02 1.332009e-01 4 2252408 2252522 115 - 1.716 1.610 -0.363
ENSG00000123933 E010 62.5874282 0.0002338652 3.200155e-01 6.450931e-01 4 2252523 2255008 2486 - 1.771 1.805 0.115
ENSG00000123933 E011 6.0391183 0.0028139711 4.959757e-01 7.777558e-01 4 2255009 2255142 134 - 0.883 0.806 -0.296
ENSG00000123933 E012 3.3214562 0.0048866231 5.296062e-01 7.984784e-01 4 2255143 2255154 12 - 0.677 0.592 -0.366
ENSG00000123933 E013 8.9136698 0.0031654890 5.552109e-02 2.634358e-01 4 2255155 2255294 140 - 1.088 0.907 -0.671
ENSG00000123933 E014 2.9622015 0.0226064811 7.191422e-01 8.969329e-01 4 2255295 2255351 57 - 0.620 0.568 -0.232
ENSG00000123933 E015 24.9051409 0.0005671296 1.977190e-01 5.151719e-01 4 2257982 2258011 30 - 1.449 1.370 -0.272
ENSG00000123933 E016 0.6057557 0.0162736378 4.249472e-01   4 2258885 2259057 173 - 0.271 0.151 -1.058
ENSG00000123933 E017 39.7022166 0.0021967647 1.102438e-04 3.194543e-03 4 2261725 2261824 100 - 1.707 1.513 -0.659
ENSG00000123933 E018 33.0911665 0.0004656195 2.028022e-06 1.049314e-04 4 2261917 2262117 201 - 1.654 1.410 -0.835

Help

Please Click HERE to learn more details about the results from DEXseq.