ENSG00000127124

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000460604 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding protein_coding_CDS_not_defined 51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 8.1482578 3.8820613 11.745278 1.1160465 1.736667 1.5947024 0.16544167 0.120900 0.202125 0.081225 0.992847247 0.006891934 FALSE TRUE
ENST00000489103 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding protein_coding_CDS_not_defined 51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 2.6217979 0.4726325 3.737187 0.3031235 1.115525 2.9568111 0.05400833 0.010950 0.074675 0.063725 0.808953081 0.006891934   FALSE
MSTRG.811.1 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding   51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 5.2517405 4.4912114 4.847105 1.5161891 2.026632 0.1097832 0.13450000 0.170175 0.098675 -0.071500 0.992847247 0.006891934 TRUE TRUE
MSTRG.811.14 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding   51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 6.2147511 7.8698488 4.296851 1.5857089 1.515842 -0.8715347 0.13905000 0.228125 0.065325 -0.162800 0.867231494 0.006891934   FALSE
MSTRG.811.16 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding   51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 0.6534527 1.9603581 0.000000 1.2248867 0.000000 -7.6223140 0.02539167 0.076175 0.000000 -0.076175 0.956554641 0.006891934   FALSE
MSTRG.811.18 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding   51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 1.6332324 4.8996972 0.000000 4.8996972 0.000000 -8.9394903 0.02600000 0.078000 0.000000 -0.078000 0.992847247 0.006891934   FALSE
MSTRG.811.19 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding   51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 10.7446913 3.9705144 15.888567 3.9705144 10.228500 1.9978700 0.13095833 0.063200 0.199800 0.136600 0.992847247 0.006891934   FALSE
MSTRG.811.3 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding   51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 7.0848417 0.0000000 8.548791 0.0000000 2.998757 9.7412632 0.13849167 0.000000 0.170325 0.170325 0.006891934 0.006891934 FALSE TRUE
MSTRG.811.8 ENSG00000127124 No_inf pgwt_inf HIVEP3 protein_coding   51.04858 35.95435 61.39683 9.095234 9.81624 0.7718319 3.5231567 3.7637379 5.566817 0.5692770 2.592667 0.5634478 0.07174167 0.111250 0.079100 -0.032150 0.992847247 0.006891934 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000127124 E001 0.6207148 3.018826e-01 3.204325e-01   1 41506316 41506364 49 - 0.124 0.321 1.732
ENSG00000127124 E002 0.5067646 4.420657e-01 2.114842e-01   1 41506365 41506369 5 - 0.066 0.321 2.731
ENSG00000127124 E003 0.6205706 3.079612e-01 3.244128e-01   1 41506370 41506370 1 - 0.123 0.321 1.732
ENSG00000127124 E004 449.4972069 7.519322e-05 1.368224e-12 2.087171e-10 1 41506371 41510229 3859 - 2.604 2.679 0.250
ENSG00000127124 E005 118.4264813 5.240142e-03 7.367318e-01 9.043819e-01 1 41510230 41511059 830 - 2.062 2.038 -0.081
ENSG00000127124 E006 23.3994185 6.277512e-03 9.775149e-01 9.967224e-01 1 41511060 41511164 105 - 1.369 1.359 -0.033
ENSG00000127124 E007 29.4327387 1.231950e-03 6.740283e-04 1.325240e-02 1 41511165 41511263 99 - 1.526 1.300 -0.781
ENSG00000127124 E008 11.3502885 1.635697e-02 5.217179e-03 5.980547e-02 1 41511264 41511266 3 - 1.156 0.834 -1.192
ENSG00000127124 E009 125.2314200 1.503870e-04 1.849787e-02 1.376187e-01 1 41512816 41513750 935 - 2.104 2.025 -0.264
ENSG00000127124 E010 19.0236850 5.528845e-03 7.108046e-02 3.025633e-01 1 41518402 41518488 87 - 1.327 1.172 -0.547
ENSG00000127124 E011 20.6756542 8.638882e-03 2.799873e-03 3.886874e-02 1 41524735 41524910 176 - 1.387 1.127 -0.915
ENSG00000127124 E012 18.0764771 1.673402e-03 1.207269e-03 2.069767e-02 1 41575544 41575689 146 - 1.334 1.063 -0.960
ENSG00000127124 E013 14.1397289 9.741143e-04 3.076866e-02 1.872734e-01 1 41579737 41579842 106 - 1.216 1.020 -0.707
ENSG00000127124 E014 21.2994575 6.786288e-04 5.565481e-01 8.145377e-01 1 41579843 41580041 199 - 1.343 1.292 -0.180
ENSG00000127124 E015 316.6138336 1.332079e-03 3.135171e-17 8.158515e-15 1 41580042 41585305 5264 - 2.535 2.346 -0.629
ENSG00000127124 E016 1.5711949 2.660633e-02 5.573497e-01 8.149919e-01 1 41585306 41585318 13 - 0.365 0.451 0.469
ENSG00000127124 E017 6.3720315 2.274276e-02 2.183581e-01 5.414180e-01 1 41628749 41628947 199 - 0.898 0.730 -0.660
ENSG00000127124 E018 0.3437845 5.845441e-01 7.050194e-01   1 41646049 41646169 121 - 0.174 0.000 -12.193
ENSG00000127124 E019 1.7122478 8.347946e-03 2.313535e-03 3.375930e-02 1 41662134 41662396 263 - 0.540 0.000 -15.439
ENSG00000127124 E020 0.2277562 1.535940e-02 6.982897e-01   1 41700916 41700995 80 - 0.124 0.000 -12.662
ENSG00000127124 E021 2.2879151 7.614403e-02 5.834462e-01 8.287265e-01 1 41841622 41841744 123 - 0.473 0.550 0.370
ENSG00000127124 E022 0.3759623 1.663781e-02 2.007896e-01   1 41847191 41847191 1 - 0.066 0.238 2.148
ENSG00000127124 E023 0.5076241 1.532490e-02 7.051167e-02   1 41847192 41847192 1 - 0.066 0.321 2.733
ENSG00000127124 E024 2.2888638 6.262872e-03 5.610646e-01 8.166428e-01 1 41847193 41847277 85 - 0.473 0.550 0.370
ENSG00000127124 E025 36.4935857 7.230674e-04 3.356003e-19 1.060457e-16 1 41847278 41847947 670 - 1.350 1.786 1.492
ENSG00000127124 E026 34.2297315 4.412388e-04 1.347696e-20 4.801597e-18 1 41847948 41848445 498 - 1.306 1.770 1.590
ENSG00000127124 E027 11.1582794 1.250110e-03 1.882452e-04 4.884578e-03 1 41848871 41849089 219 - 0.933 1.241 1.116
ENSG00000127124 E028 1.6373321 1.225117e-02 4.826378e-03 5.670940e-02 1 41864578 41864648 71 - 0.220 0.631 2.318
ENSG00000127124 E029 1.4381900 9.488199e-03 8.350207e-01 9.449565e-01 1 41864649 41864734 86 - 0.365 0.391 0.148
ENSG00000127124 E030 0.8507227 2.118830e-01 6.202115e-01 8.475314e-01 1 41864735 41864748 14 - 0.220 0.321 0.734
ENSG00000127124 E031 1.6046252 3.205120e-02 9.562972e-02 3.558721e-01 1 41865548 41865615 68 - 0.298 0.550 1.370
ENSG00000127124 E032 2.0144724 8.358893e-03 1.963726e-03 2.999896e-02 1 41869547 41869630 84 - 0.261 0.700 2.285
ENSG00000127124 E033 0.3599188 1.656487e-02 9.144108e-01   1 41869631 41869632 2 - 0.124 0.135 0.148
ENSG00000127124 E034 0.1316618 1.227401e-02 2.176529e-01   1 41898611 41898623 13 - 0.000 0.135 12.343
ENSG00000127124 E035 1.8136981 1.581361e-01 5.615568e-01 8.168911e-01 1 41918413 41918524 112 - 0.394 0.503 0.562
ENSG00000127124 E036 0.0000000       1 41918525 41918922 398 -      
ENSG00000127124 E037 0.1311489 1.226266e-02 2.175993e-01   1 41990236 41990276 41 - 0.000 0.135 12.343
ENSG00000127124 E038 0.3595497 1.640934e-02 9.148467e-01   1 42014982 42015038 57 - 0.124 0.135 0.148
ENSG00000127124 E039 3.4964918 5.223631e-03 4.017582e-01 7.127523e-01 1 42035807 42035965 159 - 0.598 0.700 0.437

Help

Please Click HERE to learn more details about the results from DEXseq.