ENSG00000127507

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000601345 ENSG00000127507 No_inf pgwt_inf ADGRE2 protein_coding protein_coding 62.96796 23.03267 85.18105 0.5192513 1.311902 1.886394 2.322434 2.287766 2.242685 0.4111494 0.1762255 -0.02858587 0.05165000 0.098275 0.026325 -0.071950 0.44455395 0.03658013 FALSE TRUE
MSTRG.14678.10 ENSG00000127507 No_inf pgwt_inf ADGRE2 protein_coding   62.96796 23.03267 85.18105 0.5192513 1.311902 1.886394 26.060458 9.932385 34.251241 0.2380540 1.4534420 1.78491352 0.41769167 0.431525 0.401750 -0.029775 1.00000000 0.03658013   FALSE
MSTRG.14678.11 ENSG00000127507 No_inf pgwt_inf ADGRE2 protein_coding   62.96796 23.03267 85.18105 0.5192513 1.311902 1.886394 8.674495 2.318575 11.371905 0.9193086 1.0041048 2.28922310 0.12955000 0.099900 0.133950 0.034050 0.99284725 0.03658013 FALSE TRUE
MSTRG.14678.13 ENSG00000127507 No_inf pgwt_inf ADGRE2 protein_coding   62.96796 23.03267 85.18105 0.5192513 1.311902 1.886394 8.482346 3.248854 11.098068 1.1135438 1.6868588 1.76917126 0.13675833 0.143700 0.129600 -0.014100 1.00000000 0.03658013 TRUE TRUE
MSTRG.14678.14 ENSG00000127507 No_inf pgwt_inf ADGRE2 protein_coding   62.96796 23.03267 85.18105 0.5192513 1.311902 1.886394 5.267963 0.000000 7.788308 0.0000000 2.9342708 9.60701733 0.06500833 0.000000 0.091775 0.091775 0.03658013 0.03658013 TRUE TRUE
MSTRG.14678.7 ENSG00000127507 No_inf pgwt_inf ADGRE2 protein_coding   62.96796 23.03267 85.18105 0.5192513 1.311902 1.886394 1.374434 1.522395 1.084530 0.9943725 1.0845300 -0.48547704 0.03195833 0.064925 0.013100 -0.051825 0.99284725 0.03658013 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000127507 E001 0.0000000       19 14732388 14732391 4 -      
ENSG00000127507 E002 0.0000000       19 14732392 14732395 4 -      
ENSG00000127507 E003 0.0000000       19 14732396 14732454 59 -      
ENSG00000127507 E004 0.0000000       19 14732455 14732507 53 -      
ENSG00000127507 E005 0.0000000       19 14732508 14732531 24 -      
ENSG00000127507 E006 0.0000000       19 14732532 14732545 14 -      
ENSG00000127507 E007 0.0000000       19 14732546 14732604 59 -      
ENSG00000127507 E008 0.0000000       19 14732605 14732609 5 -      
ENSG00000127507 E009 0.0000000       19 14732610 14732640 31 -      
ENSG00000127507 E010 0.0000000       19 14732641 14732704 64 -      
ENSG00000127507 E011 365.5021769 6.584162e-05 8.081148e-01 9.346518e-01 19 14732705 14735575 2871 - 2.494 2.491 -0.008
ENSG00000127507 E012 119.9124927 2.177739e-03 5.530230e-01 8.125956e-01 19 14735576 14736078 503 - 2.006 2.029 0.077
ENSG00000127507 E013 29.9003574 5.363461e-04 9.013912e-01 9.706670e-01 19 14736079 14736106 28 - 1.423 1.416 -0.023
ENSG00000127507 E014 46.6576482 1.776906e-03 4.689969e-01 7.603335e-01 19 14736107 14736235 129 - 1.617 1.579 -0.132
ENSG00000127507 E015 15.5471921 3.075910e-03 1.243732e-01 4.084428e-01 19 14736236 14736244 9 - 1.182 1.039 -0.515
ENSG00000127507 E016 1.5697932 1.767572e-01 2.247555e-01 5.490736e-01 19 14737525 14737644 120 - 0.304 0.527 1.223
ENSG00000127507 E017 6.0368284 2.515764e-03 1.271560e-06 7.002287e-05 19 14741475 14742086 612 - 0.593 1.124 2.077
ENSG00000127507 E018 36.5975745 2.190380e-03 8.035614e-01 9.327820e-01 19 14743420 14743530 111 - 1.509 1.495 -0.048
ENSG00000127507 E019 35.7454388 3.931651e-04 5.912788e-01 8.332236e-01 19 14743616 14743763 148 - 1.488 1.521 0.111
ENSG00000127507 E020 11.7411384 1.395768e-03 5.913632e-01 8.332236e-01 19 14743764 14743784 21 - 1.052 0.999 -0.191
ENSG00000127507 E021 23.9075245 5.851146e-04 9.987982e-01 1.000000e+00 19 14746232 14746323 92 - 1.328 1.329 0.005
ENSG00000127507 E022 18.0921985 8.195122e-04 3.721797e-01 6.902194e-01 19 14746896 14746962 67 - 1.196 1.267 0.252
ENSG00000127507 E023 21.1096079 2.755342e-03 7.141571e-01 8.939420e-01 19 14751436 14751502 67 - 1.270 1.299 0.104
ENSG00000127507 E024 36.5838371 3.756242e-03 2.362830e-01 5.615491e-01 19 14751503 14751671 169 - 1.523 1.447 -0.261
ENSG00000127507 E025 23.4352353 3.962072e-03 9.828296e-01 9.986305e-01 19 14752329 14752421 93 - 1.320 1.319 -0.002
ENSG00000127507 E026 21.1638932 6.752075e-04 6.946229e-01 8.840083e-01 19 14752422 14752526 105 - 1.284 1.256 -0.099
ENSG00000127507 E027 25.2376950 1.069541e-03 7.811196e-01 9.242097e-01 19 14754954 14755127 174 - 1.346 1.366 0.071
ENSG00000127507 E028 27.1463811 4.994931e-04 9.258560e-02 3.494738e-01 19 14755654 14755844 191 - 1.406 1.289 -0.407
ENSG00000127507 E029 6.9575277 2.124023e-03 8.736326e-01 9.602597e-01 19 14755845 14755877 33 - 0.834 0.854 0.077
ENSG00000127507 E030 15.6813598 9.607662e-04 4.667233e-03 5.554017e-02 19 14756238 14756345 108 - 1.206 0.933 -0.994
ENSG00000127507 E031 21.7453122 6.693649e-04 6.910045e-01 8.823039e-01 19 14764433 14764610 178 - 1.296 1.267 -0.099
ENSG00000127507 E032 10.4044308 1.274519e-03 5.458030e-01 8.085734e-01 19 14765320 14765397 78 - 0.977 1.039 0.227
ENSG00000127507 E033 3.0182862 4.621215e-03 2.002905e-01 5.186410e-01 19 14765524 14765570 47 - 0.593 0.384 -1.038
ENSG00000127507 E034 0.9317475 7.619244e-02 5.736959e-01 8.239211e-01 19 14765658 14765804 147 - 0.276 0.168 -0.907
ENSG00000127507 E035 2.4201513 7.729332e-03 6.008428e-02 2.756576e-01 19 14765805 14766063 259 - 0.401 0.680 1.316
ENSG00000127507 E036 4.8216784 9.560160e-02 7.094667e-02 3.022630e-01 19 14766064 14766234 171 - 0.620 0.908 1.164
ENSG00000127507 E037 3.8522042 3.839036e-03 3.809889e-01 6.972858e-01 19 14766235 14766381 147 - 0.658 0.527 -0.585
ENSG00000127507 E038 3.7897445 3.807820e-03 6.081534e-01 8.416610e-01 19 14766978 14767085 108 - 0.606 0.680 0.316
ENSG00000127507 E039 4.9833062 2.889266e-03 4.430155e-01 7.429173e-01 19 14767086 14767109 24 - 0.693 0.793 0.406
ENSG00000127507 E040 1.7623298 1.832867e-01 8.966504e-01 9.689877e-01 19 14768791 14768934 144 - 0.401 0.384 -0.099
ENSG00000127507 E041 2.4996701 5.923774e-03 4.294042e-01 7.328987e-01 19 14771880 14772341 462 - 0.462 0.584 0.579
ENSG00000127507 E042 25.0388375 6.857756e-04 4.962042e-01 7.778234e-01 19 14772342 14772497 156 - 1.336 1.383 0.167
ENSG00000127507 E043 19.2686928 8.472695e-03 4.458180e-01 7.445312e-01 19 14773938 14774054 117 - 1.223 1.289 0.232
ENSG00000127507 E044 9.4988049 1.623759e-03 5.529295e-01 8.124898e-01 19 14774256 14774306 51 - 0.971 0.908 -0.237
ENSG00000127507 E045 0.9982025 6.126365e-02 1.683532e-02 1.298445e-01 19 14776404 14776725 322 - 0.140 0.527 2.638
ENSG00000127507 E046 8.6840790 2.824323e-03 6.323784e-01 8.533011e-01 19 14776726 14776927 202 - 0.935 0.882 -0.199
ENSG00000127507 E047 0.2291896 2.661629e-01 1.000000e+00   19 14777047 14777086 40 - 0.098 0.000 -8.449
ENSG00000127507 E048 0.0000000       19 14778257 14778560 304 -      

Help

Please Click HERE to learn more details about the results from DEXseq.