ENSG00000131748

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336308 ENSG00000131748 No_inf pgwt_inf STARD3 protein_coding protein_coding 47.87412 42.78069 49.191 2.691327 2.43763 0.2013909 14.1501155 10.570367 15.314365 2.0330858 0.8239608 0.5344376 0.29492500 0.243725 0.311500 0.067775 0.992847247 0.001182268 FALSE TRUE
ENST00000484773 ENSG00000131748 No_inf pgwt_inf STARD3 protein_coding retained_intron 47.87412 42.78069 49.191 2.691327 2.43763 0.2013909 0.8950633 2.685190 0.000000 1.5879780 0.0000000 -8.0742431 0.02231667 0.066950 0.000000 -0.066950 0.971653840 0.001182268 FALSE TRUE
ENST00000578232 ENSG00000131748 No_inf pgwt_inf STARD3 protein_coding protein_coding_CDS_not_defined 47.87412 42.78069 49.191 2.691327 2.43763 0.2013909 4.0884407 3.281034 0.000000 1.9908134 0.0000000 -8.3623973 0.08669167 0.086850 0.000000 -0.086850 0.977009320 0.001182268   FALSE
ENST00000580551 ENSG00000131748 No_inf pgwt_inf STARD3 protein_coding retained_intron 47.87412 42.78069 49.191 2.691327 2.43763 0.2013909 12.0580325 7.679148 17.568123 3.1253900 2.1405208 1.1928853 0.24545833 0.168175 0.360550 0.192375 0.992847247 0.001182268 FALSE FALSE
ENST00000583884 ENSG00000131748 No_inf pgwt_inf STARD3 protein_coding nonsense_mediated_decay 47.87412 42.78069 49.191 2.691327 2.43763 0.2013909 6.1121818 6.135340 8.027476 2.1159485 3.8371452 0.3872498 0.12219167 0.137050 0.154850 0.017800 1.000000000 0.001182268 FALSE FALSE
ENST00000584850 ENSG00000131748 No_inf pgwt_inf STARD3 protein_coding retained_intron 47.87412 42.78069 49.191 2.691327 2.43763 0.2013909 1.1144463 2.736866 0.000000 0.4341074 0.0000000 -8.1016429 0.02610833 0.066575 0.000000 -0.066575 0.001182268 0.001182268 FALSE TRUE
MSTRG.12611.3 ENSG00000131748 No_inf pgwt_inf STARD3 protein_coding   47.87412 42.78069 49.191 2.691327 2.43763 0.2013909 1.9060247 3.486205 1.385686 2.0310820 0.9995550 -1.3248154 0.04597500 0.090650 0.030175 -0.060475 1.000000000 0.001182268 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000131748 E001 0.0000000       17 39637085 39637089 5 +      
ENSG00000131748 E002 0.3420755 0.0371439066 0.096679994729051   17 39637090 39637117 28 + 0.244 0.000 -11.335
ENSG00000131748 E003 0.9799056 0.0268431137 0.945755889948754 0.9863626067379 17 39637118 39637138 21 + 0.302 0.291 -0.073
ENSG00000131748 E004 0.9799056 0.0268431137 0.945755889948754 0.9863626067379 17 39637139 39637139 1 + 0.302 0.291 -0.073
ENSG00000131748 E005 0.9799056 0.0268431137 0.945755889948754 0.9863626067379 17 39637140 39637140 1 + 0.302 0.291 -0.073
ENSG00000131748 E006 1.0945004 0.0122472302 0.687339244888587 0.8806528891018 17 39637141 39637141 1 + 0.353 0.291 -0.395
ENSG00000131748 E007 1.0945004 0.0122472302 0.687339244888587 0.8806528891018 17 39637142 39637143 2 + 0.353 0.291 -0.395
ENSG00000131748 E008 1.0945004 0.0122472302 0.687339244888587 0.8806528891018 17 39637144 39637146 3 + 0.353 0.291 -0.395
ENSG00000131748 E009 1.2084507 0.0212701968 0.486976610073103 0.7725901892454 17 39637147 39637152 6 + 0.399 0.291 -0.658
ENSG00000131748 E010 2.5848502 0.0055378853 0.916916594577818 0.9755182543992 17 39637153 39637161 9 + 0.545 0.559 0.065
ENSG00000131748 E011 12.5836947 0.0133319161 0.409364554780306 0.7182933432460 17 39637162 39637231 70 + 1.171 1.096 -0.269
ENSG00000131748 E012 0.0000000       17 39637370 39637515 146 +      
ENSG00000131748 E013 0.1139502 0.0112659395 0.512610949269731   17 39651752 39651754 3 + 0.097 0.000 -12.471
ENSG00000131748 E014 0.1139502 0.0112659395 0.512610949269731   17 39651755 39651845 91 + 0.097 0.000 -12.471
ENSG00000131748 E015 0.0000000       17 39652489 39652731 243 +      
ENSG00000131748 E016 0.0000000       17 39652778 39652820 43 +      
ENSG00000131748 E017 0.0000000       17 39653049 39653097 49 +      
ENSG00000131748 E018 0.0000000       17 39653098 39653124 27 +      
ENSG00000131748 E019 0.0000000       17 39653125 39653158 34 +      
ENSG00000131748 E020 0.0000000       17 39653159 39653195 37 +      
ENSG00000131748 E021 12.3919771 0.0178938264 0.753011633321905 0.9117410721313 17 39653481 39653499 19 + 1.140 1.112 -0.101
ENSG00000131748 E022 10.5932835 0.0433834975 0.849010211965474 0.9503674387526 17 39653500 39653515 16 + 1.053 1.070 0.061
ENSG00000131748 E023 9.9523044 0.0407551867 0.976028674694970 0.9961636172660 17 39653516 39653534 19 + 1.043 1.033 -0.037
ENSG00000131748 E024 17.8827024 0.0007949916 0.528694713949647 0.7979418140959 17 39653535 39653617 83 + 1.297 1.254 -0.152
ENSG00000131748 E025 38.8702180 0.0004398534 0.020092859851789 0.1446108403053 17 39653618 39653750 133 + 1.655 1.546 -0.372
ENSG00000131748 E026 0.6395028 0.0310353168 0.196247429093490   17 39656898 39656909 12 + 0.097 0.291 1.927
ENSG00000131748 E027 1.1476398 0.0106858568 0.104076335011971 0.3716858394619 17 39656910 39657007 98 + 0.177 0.427 1.735
ENSG00000131748 E028 29.8219545 0.0005413247 0.602832565619242 0.8387139526801 17 39657008 39657085 78 + 1.472 1.499 0.094
ENSG00000131748 E029 21.4910576 0.0010417409 0.376527416492019 0.6940634894231 17 39657775 39657839 65 + 1.319 1.374 0.193
ENSG00000131748 E030 8.5448913 0.0015896628 0.382667135347656 0.6988058827817 17 39657840 39657852 13 + 0.931 1.013 0.306
ENSG00000131748 E031 0.1141751 0.0112201659 0.512696601237873   17 39657853 39657887 35 + 0.097 0.000 -12.472
ENSG00000131748 E032 0.1316618 0.0123303910 0.564694486962046   17 39657911 39657934 24 + 0.000 0.093 11.586
ENSG00000131748 E033 0.2628107 0.0161150225 0.259649661439405   17 39657935 39657972 38 + 0.000 0.170 12.527
ENSG00000131748 E034 15.0902749 0.0009009346 0.320194045157147 0.6450931400866 17 39657973 39658026 54 + 1.163 1.236 0.260
ENSG00000131748 E035 3.2983990 0.1263507604 0.121686059034386 0.4036423741712 17 39658027 39658267 241 + 0.441 0.743 1.368
ENSG00000131748 E036 2.3579992 0.0976155952 0.685926105213055 0.8803007166624 17 39658268 39658393 126 + 0.478 0.559 0.387
ENSG00000131748 E037 1.7691595 0.2781265623 0.311917776794567 0.6379664981343 17 39658394 39658404 11 + 0.302 0.530 1.249
ENSG00000131748 E038 9.4886737 0.0032877509 0.731060971325831 0.9018830879298 17 39658405 39658412 8 + 1.002 1.033 0.115
ENSG00000131748 E039 14.2324964 0.0015638822 0.791863528860792 0.9282590060221 17 39658413 39658445 33 + 1.192 1.172 -0.073
ENSG00000131748 E040 19.6674352 0.0164166907 0.076451346837339 0.3145968498523 17 39658446 39658522 77 + 1.386 1.242 -0.503
ENSG00000131748 E041 5.2113068 0.0027441787 0.001506975896454 0.0245171077043 17 39658523 39658708 186 + 0.545 0.924 1.560
ENSG00000131748 E042 1.8214620 0.0152314178 0.000873441348814 0.0161954269798 17 39658709 39658721 13 + 0.097 0.613 3.628
ENSG00000131748 E043 23.7287978 0.0034538691 0.999399878405717 1.0000000000000 17 39658722 39658820 99 + 1.391 1.392 0.002
ENSG00000131748 E044 0.0000000       17 39658989 39659050 62 +      
ENSG00000131748 E045 10.6416056 0.0014449588 0.399704479739474 0.7115143236525 17 39659051 39659063 13 + 1.023 1.095 0.264
ENSG00000131748 E046 15.4660831 0.0016536615 0.292451964098464 0.6206768393084 17 39659064 39659106 43 + 1.171 1.248 0.275
ENSG00000131748 E047 32.1583185 0.0004640679 0.591494725939783 0.8332236455795 17 39659461 39659553 93 + 1.504 1.531 0.093
ENSG00000131748 E048 14.7788950 0.0016868668 0.000000007133542 0.0000006301018 17 39659554 39660159 606 + 0.877 1.352 1.719
ENSG00000131748 E049 4.2130458 0.0032951770 0.001180807657696 0.0203388563648 17 39660160 39660195 36 + 0.441 0.858 1.820
ENSG00000131748 E050 3.0643092 0.0048094716 0.005085899533891 0.0589755488546 17 39660196 39660210 15 + 0.353 0.743 1.853
ENSG00000131748 E051 20.6835556 0.0069928791 0.448279020157667 0.7466380508095 17 39660211 39660219 9 + 1.364 1.308 -0.192
ENSG00000131748 E052 29.1613763 0.0094949044 0.534207588799257 0.8011777354315 17 39660220 39660273 54 + 1.500 1.458 -0.145
ENSG00000131748 E053 0.9991990 0.0119958165 0.526533191077509 0.7966457213487 17 39660274 39660285 12 + 0.244 0.341 0.664
ENSG00000131748 E054 2.1480116 0.0653475513 0.154498716854629 0.4550190781107 17 39660286 39660430 145 + 0.353 0.587 1.191
ENSG00000131748 E055 33.7319587 0.0005486840 0.166379901433520 0.4724242323224 17 39660431 39660526 96 + 1.576 1.506 -0.240
ENSG00000131748 E056 29.9016994 0.0005497727 0.518573276118190 0.7918408357506 17 39660810 39660889 80 + 1.507 1.472 -0.120
ENSG00000131748 E057 27.6994419 0.0010229706 0.527316514534962 0.7972407624764 17 39660981 39661085 105 + 1.475 1.439 -0.124
ENSG00000131748 E058 0.9649999 0.1745384704 0.516158351810767 0.7904679859285 17 39661086 39661321 236 + 0.353 0.235 -0.810
ENSG00000131748 E059 32.9119727 0.0066706903 0.362042436347118 0.6814151914817 17 39662251 39662344 94 + 1.558 1.502 -0.191
ENSG00000131748 E060 1.8994977 0.0078053672 0.083867333890149 0.3312142007806 17 39662345 39662367 23 + 0.302 0.559 1.387
ENSG00000131748 E061 4.2232805 0.0034222694 0.380764248195159 0.6970548489385 17 39662368 39662803 436 + 0.655 0.762 0.442
ENSG00000131748 E062 128.9835730 0.0001327344 0.062086364391318 0.2803562492470 17 39662804 39664279 1476 + 2.136 2.091 -0.152

Help

Please Click HERE to learn more details about the results from DEXseq.