ENSG00000133226

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323848 ENSG00000133226 No_inf pgwt_inf SRRM1 protein_coding protein_coding 42.85702 42.25822 45.21196 0.5666753 1.33648 0.09744998 9.654082 5.284419 11.703620 3.1147504 2.3054276 1.1456428 0.22685000 0.127850 0.263400 0.135550 9.788993e-01 6.824374e-05 FALSE TRUE
ENST00000462710 ENSG00000133226 No_inf pgwt_inf SRRM1 protein_coding retained_intron 42.85702 42.25822 45.21196 0.5666753 1.33648 0.09744998 2.939645 4.180491 2.941075 0.3601322 0.3879693 -0.5058790 0.06830000 0.098700 0.065175 -0.033525 9.928472e-01 6.824374e-05   FALSE
ENST00000705662 ENSG00000133226 No_inf pgwt_inf SRRM1 protein_coding protein_coding 42.85702 42.25822 45.21196 0.5666753 1.33648 0.09744998 14.199789 18.506609 14.764478 2.4028274 1.4279992 -0.3257127 0.33151667 0.436100 0.325400 -0.110700 9.928472e-01 6.824374e-05 FALSE TRUE
ENST00000705682 ENSG00000133226 No_inf pgwt_inf SRRM1 protein_coding protein_coding 42.85702 42.25822 45.21196 0.5666753 1.33648 0.09744998 4.049787 0.000000 7.596426 0.0000000 1.8739951 9.5710750 0.09337500 0.000000 0.166625 0.166625 6.824374e-05 6.824374e-05 FALSE TRUE
MSTRG.462.24 ENSG00000133226 No_inf pgwt_inf SRRM1 protein_coding   42.85702 42.25822 45.21196 0.5666753 1.33648 0.09744998 2.402484 5.506205 1.701246 0.9666091 0.7525310 -1.6886289 0.05563333 0.129625 0.037275 -0.092350 8.449595e-01 6.824374e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000133226 E001 0.0000000       1 24631716 24631777 62 +      
ENSG00000133226 E002 0.0000000       1 24633019 24633065 47 +      
ENSG00000133226 E003 0.0000000       1 24633066 24633099 34 +      
ENSG00000133226 E004 0.0000000       1 24635644 24635877 234 +      
ENSG00000133226 E005 0.0000000       1 24641231 24641392 162 +      
ENSG00000133226 E006 0.6383430 0.0149008953 1.309420e-01   1 24643200 24643271 72 + 0.089 0.312 2.199
ENSG00000133226 E007 0.7529378 0.0138779183 3.265979e-01 0.6510128433 1 24643272 24643272 1 + 0.163 0.312 1.199
ENSG00000133226 E008 0.7529378 0.0138779183 3.265979e-01 0.6510128433 1 24643273 24643274 2 + 0.163 0.312 1.199
ENSG00000133226 E009 1.2432970 0.0107541286 4.009107e-01 0.7122064402 1 24643275 24643287 13 + 0.282 0.411 0.784
ENSG00000133226 E010 1.9961745 0.0948028860 2.989438e-01 0.6263981529 1 24643288 24643292 5 + 0.375 0.559 0.935
ENSG00000133226 E011 2.2242164 0.0088128348 4.549278e-01 0.7513103525 1 24643293 24643298 6 + 0.452 0.559 0.520
ENSG00000133226 E012 2.9435434 0.0184707091 7.549642e-01 0.9127490107 1 24643299 24643301 3 + 0.573 0.618 0.198
ENSG00000133226 E013 2.8130463 0.0055385206 9.058406e-01 0.9722384745 1 24643302 24643304 3 + 0.573 0.589 0.073
ENSG00000133226 E014 2.8130463 0.0055385206 9.058406e-01 0.9722384745 1 24643305 24643307 3 + 0.573 0.589 0.073
ENSG00000133226 E015 12.9913113 0.0011095491 6.103719e-01 0.8428672353 1 24643308 24643347 40 + 1.125 1.165 0.144
ENSG00000133226 E016 0.3762480 0.1811883386 5.453787e-01   1 24643559 24643732 174 + 0.089 0.183 1.199
ENSG00000133226 E017 22.8382016 0.0108966192 9.794269e-01 0.9973692904 1 24645984 24646073 90 + 1.378 1.377 -0.002
ENSG00000133226 E018 27.9784223 0.0077198293 1.756355e-02 0.1337126950 1 24646667 24646789 123 + 1.533 1.377 -0.538
ENSG00000133226 E019 4.3391268 0.0036512666 2.165783e-01 0.5395816679 1 24646790 24647078 289 + 0.646 0.796 0.614
ENSG00000133226 E020 5.4680909 0.0101892962 1.125578e-01 0.3880183940 1 24647079 24647208 130 + 0.709 0.893 0.729
ENSG00000133226 E021 13.0359281 0.0163901417 3.752558e-01 0.6929600570 1 24647209 24647813 605 + 1.102 1.188 0.307
ENSG00000133226 E022 6.4338933 0.0023467468 1.893254e-01 0.5036596546 1 24647814 24648023 210 + 0.796 0.935 0.533
ENSG00000133226 E023 6.4692269 0.0174049511 8.742918e-02 0.3390259478 1 24648024 24648166 143 + 0.763 0.961 0.761
ENSG00000133226 E024 11.4985118 0.0139456563 2.550131e-05 0.0009407663 1 24648167 24648533 367 + 0.841 1.256 1.521
ENSG00000133226 E025 3.8473826 0.0037538876 2.054195e-01 0.5251324111 1 24648534 24648617 84 + 0.599 0.757 0.668
ENSG00000133226 E026 7.6900988 0.0491788024 1.451622e-01 0.4408514072 1 24648618 24648858 241 + 0.841 1.019 0.668
ENSG00000133226 E027 38.3690334 0.0003827654 1.339195e-01 0.4240762975 1 24648859 24649029 171 + 1.629 1.558 -0.243
ENSG00000133226 E028 15.7297302 0.0118335474 2.016471e-01 0.5206570344 1 24649971 24649987 17 + 1.275 1.165 -0.386
ENSG00000133226 E029 33.5649438 0.0049276195 1.602870e-02 0.1257424852 1 24649988 24650086 99 + 1.603 1.463 -0.478
ENSG00000133226 E030 0.4904200 0.0157332395 8.915237e-01   1 24650565 24650627 63 + 0.163 0.183 0.199
ENSG00000133226 E031 26.8515541 0.0005023759 3.719325e-02 0.2096798459 1 24651409 24651498 90 + 1.500 1.382 -0.408
ENSG00000133226 E032 13.3956111 0.0069680052 6.976873e-01 0.8851701433 1 24651499 24651519 21 + 1.174 1.141 -0.117
ENSG00000133226 E033 24.4337915 0.0015197134 3.601076e-01 0.6796797069 1 24651520 24651612 93 + 1.432 1.377 -0.191
ENSG00000133226 E034 20.6584141 0.0357783532 9.353411e-01 0.9822750735 1 24652434 24652496 63 + 1.329 1.342 0.045
ENSG00000133226 E035 24.1037387 0.0013205335 5.537872e-01 0.8130907737 1 24652497 24652628 132 + 1.417 1.382 -0.123
ENSG00000133226 E036 9.7844941 0.0057710101 8.734158e-01 0.9602137041 1 24652913 24652927 15 + 1.025 1.040 0.054
ENSG00000133226 E037 23.1646797 0.0141736427 7.889074e-01 0.9268660344 1 24652928 24653032 105 + 1.394 1.372 -0.076
ENSG00000133226 E038 0.7371896 0.0145336852 8.676005e-01 0.9580066365 1 24654306 24654343 38 + 0.227 0.252 0.199
ENSG00000133226 E039 31.6740531 0.0009144986 1.547562e-01 0.4554696715 1 24654855 24655010 156 + 1.550 1.475 -0.258
ENSG00000133226 E040 12.2890097 0.0026055604 3.871712e-01 0.7017140780 1 24655011 24655021 11 + 1.086 1.158 0.256
ENSG00000133226 E041 15.4721306 0.0011387846 7.048588e-01 0.8895271347 1 24655022 24655053 32 + 1.230 1.203 -0.098
ENSG00000133226 E042 20.5071229 0.0006469576 2.343265e-01 0.5597415075 1 24655054 24655123 70 + 1.369 1.293 -0.266
ENSG00000133226 E043 7.5374352 0.0019243802 6.358726e-01 0.8549485339 1 24655124 24655129 6 + 0.954 0.907 -0.176
ENSG00000133226 E044 20.0993169 0.0006932015 6.575584e-01 0.8663239465 1 24660719 24660799 81 + 1.338 1.310 -0.100
ENSG00000133226 E045 0.0000000       1 24660800 24660975 176 +      
ENSG00000133226 E046 8.2146059 0.0017751542 6.631472e-01 0.8686727012 1 24661310 24661312 3 + 0.943 0.985 0.156
ENSG00000133226 E047 20.9405872 0.0006383522 6.070738e-01 0.8411976164 1 24661313 24661396 84 + 1.325 1.357 0.114
ENSG00000133226 E048 0.2620121 0.0160502402 1.989923e-01   1 24661397 24661405 9 + 0.000 0.183 9.290
ENSG00000133226 E049 30.5854288 0.0026279894 1.763729e-01 0.4875003430 1 24662660 24662804 145 + 1.536 1.459 -0.263
ENSG00000133226 E050 3.1456211 0.0081851550 3.462966e-02 0.2008028491 1 24662805 24663068 264 + 0.452 0.737 1.286
ENSG00000133226 E051 10.5844432 0.0042414742 6.040657e-01 0.8392512742 1 24663183 24663224 42 + 1.086 1.040 -0.168
ENSG00000133226 E052 2.2944171 0.0064864611 7.447652e-03 0.0765768026 1 24666555 24666814 260 + 0.282 0.669 2.006
ENSG00000133226 E053 28.8590975 0.0006063763 7.854122e-01 0.9256021550 1 24666815 24666925 111 + 1.467 1.483 0.052
ENSG00000133226 E054 70.4005893 0.0002170393 7.499589e-01 0.9103229545 1 24669123 24669582 460 + 1.859 1.848 -0.037
ENSG00000133226 E055 12.1021307 0.0019987961 1.936711e-01 0.5096273133 1 24669583 24669587 5 + 1.168 1.060 -0.386
ENSG00000133226 E056 3.0122670 0.0052590524 5.068259e-02 0.2497016964 1 24669588 24670119 532 + 0.452 0.716 1.199
ENSG00000133226 E057 40.8405998 0.0010658458 7.893616e-01 0.9271217358 1 24670120 24670315 196 + 1.615 1.628 0.043
ENSG00000133226 E058 41.8430514 0.0004219977 6.074441e-01 0.8413777319 1 24671386 24671595 210 + 1.620 1.644 0.080
ENSG00000133226 E059 175.1055927 0.0001021823 4.563010e-02 0.2347891119 1 24672182 24673281 1100 + 2.224 2.266 0.140

Help

Please Click HERE to learn more details about the results from DEXseq.