ENSG00000133706

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000274562 ENSG00000133706 No_inf pgwt_inf LARS1 protein_coding protein_coding 59.44374 36.34381 71.63905 0.706387 1.945352 0.978841 21.653146 15.987299 26.794613 0.5366905 0.6127917 0.7446530 0.376500 0.439875 0.374800 -0.065075 0.9928472467 0.0003699716 FALSE TRUE
ENST00000394434 ENSG00000133706 No_inf pgwt_inf LARS1 protein_coding protein_coding 59.44374 36.34381 71.63905 0.706387 1.945352 0.978841 12.454809 9.990909 13.236140 0.4097174 1.0271339 0.4054410 0.220375 0.274725 0.185250 -0.089475 0.9928472467 0.0003699716 FALSE TRUE
ENST00000508667 ENSG00000133706 No_inf pgwt_inf LARS1 protein_coding retained_intron 59.44374 36.34381 71.63905 0.706387 1.945352 0.978841 7.853166 6.320050 9.310978 0.6385255 1.8283536 0.5582644 0.138150 0.173425 0.128250 -0.045175 0.9928472467 0.0003699716 FALSE TRUE
ENST00000510191 ENSG00000133706 No_inf pgwt_inf LARS1 protein_coding protein_coding 59.44374 36.34381 71.63905 0.706387 1.945352 0.978841 8.786809 0.000000 8.561748 0.0000000 2.2880710 9.7434456 0.123575 0.000000 0.117700 0.117700 0.0003699716 0.0003699716 FALSE TRUE
MSTRG.23717.20 ENSG00000133706 No_inf pgwt_inf LARS1 protein_coding   59.44374 36.34381 71.63905 0.706387 1.945352 0.978841 1.723345 0.000000 5.170034 0.0000000 2.1855348 9.0168178 0.024925 0.000000 0.074775 0.074775 0.0452087444 0.0003699716 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000133706 E001 1.2450532 0.0958131145 1.152281e-01 3.923436e-01 5 146110566 146113033 2468 - 0.227 0.490 1.604
ENSG00000133706 E002 0.4905571 0.0162174361 4.867575e-01   5 146113034 146113042 9 - 0.128 0.230 1.019
ENSG00000133706 E003 56.4621568 0.0003907618 1.001961e-06 5.676637e-05 5 146113043 146113895 853 - 1.660 1.858 0.669
ENSG00000133706 E004 6.3139974 0.0022453910 1.695980e-01 4.770988e-01 5 146113896 146113910 15 - 0.790 0.938 0.571
ENSG00000133706 E005 91.4217977 0.0001557214 9.569123e-01 9.894582e-01 5 146113911 146114232 322 - 1.948 1.950 0.007
ENSG00000133706 E006 22.1108625 0.0005792557 6.190684e-01 8.468796e-01 5 146114233 146114311 79 - 1.359 1.327 -0.112
ENSG00000133706 E007 0.1316618 0.0122892067 2.512012e-01   5 146119009 146119074 66 - 0.000 0.130 10.959
ENSG00000133706 E008 40.1238544 0.0044806626 1.607205e-01 4.636457e-01 5 146120371 146120503 133 - 1.568 1.646 0.266
ENSG00000133706 E009 60.7800831 0.0002859004 3.588850e-01 6.786911e-01 5 146122492 146122587 96 - 1.760 1.797 0.124
ENSG00000133706 E010 0.0000000       5 146123979 146123981 3 -      
ENSG00000133706 E011 54.1191881 0.0002548235 3.726863e-01 6.906676e-01 5 146123982 146124086 105 - 1.738 1.700 -0.127
ENSG00000133706 E012 50.1530213 0.0002866902 7.890021e-01 9.269252e-01 5 146126435 146126545 111 - 1.696 1.685 -0.038
ENSG00000133706 E013 54.0806917 0.0002847044 7.733769e-01 9.210955e-01 5 146128672 146128779 108 - 1.720 1.732 0.043
ENSG00000133706 E014 23.3194248 0.0005540388 7.050844e-01 8.896257e-01 5 146128780 146128782 3 - 1.378 1.354 -0.082
ENSG00000133706 E015 51.1749086 0.0002877078 4.019652e-01 7.129782e-01 5 146128978 146129081 104 - 1.687 1.724 0.124
ENSG00000133706 E016 28.6395405 0.0059001778 3.864828e-01 7.010916e-01 5 146129082 146129118 37 - 1.434 1.491 0.197
ENSG00000133706 E017 55.1487358 0.0002733757 8.512858e-01 9.513169e-01 5 146130018 146130158 141 - 1.729 1.738 0.028
ENSG00000133706 E018 2.7334899 0.0054705162 1.375550e-02 1.144194e-01 5 146130159 146130867 709 - 0.406 0.743 1.549
ENSG00000133706 E019 0.4910646 0.0158456265 4.868896e-01   5 146130868 146130935 68 - 0.128 0.230 1.019
ENSG00000133706 E020 0.6050148 0.0149170652 7.478247e-01   5 146130936 146131018 83 - 0.181 0.230 0.434
ENSG00000133706 E021 33.1296341 0.0005613206 6.455507e-01 8.600323e-01 5 146131019 146131109 91 - 1.525 1.501 -0.084
ENSG00000133706 E022 14.4887887 0.0009488399 2.290885e-01 5.543275e-01 5 146131110 146132897 1788 - 1.138 1.231 0.333
ENSG00000133706 E023 48.0941261 0.0003524314 6.745445e-01 8.742881e-01 5 146132898 146133081 184 - 1.681 1.662 -0.063
ENSG00000133706 E024 22.4090997 0.0210185357 4.121505e-01 7.203576e-01 5 146135601 146135664 64 - 1.378 1.305 -0.255
ENSG00000133706 E025 0.0000000       5 146139616 146139703 88 -      
ENSG00000133706 E026 22.9925161 0.0006105875 4.633849e-02 2.369603e-01 5 146140204 146140261 58 - 1.314 1.439 0.434
ENSG00000133706 E027 44.4171879 0.0004860958 5.211218e-09 4.680926e-07 5 146140262 146142855 2594 - 1.525 1.790 0.899
ENSG00000133706 E028 1.3243391 0.1425046667 8.603037e-01 9.550414e-01 5 146142856 146142871 16 - 0.343 0.379 0.211
ENSG00000133706 E029 27.2531897 0.0005063727 1.520268e-01 4.512943e-01 5 146142872 146142990 119 - 1.402 1.486 0.289
ENSG00000133706 E030 22.8014412 0.0020509993 4.384325e-01 7.397629e-01 5 146142991 146143084 94 - 1.378 1.327 -0.179
ENSG00000133706 E031 1.1752861 0.0106181048 3.636010e-01 6.830108e-01 5 146143085 146143105 21 - 0.376 0.230 -0.981
ENSG00000133706 E032 3.2241476 0.0048400238 1.123883e-02 1.003742e-01 5 146143244 146143411 168 - 0.461 0.794 1.466
ENSG00000133706 E033 21.2275183 0.0020525011 3.616010e-01 6.811422e-01 5 146143412 146143486 75 - 1.352 1.289 -0.219
ENSG00000133706 E034 21.7665447 0.0057056047 7.589889e-01 9.144937e-01 5 146143487 146143550 64 - 1.349 1.327 -0.077
ENSG00000133706 E035 26.8642381 0.0084138463 8.094426e-01 9.352095e-01 5 146144267 146144349 83 - 1.422 1.439 0.057
ENSG00000133706 E036 0.3589885 0.0164921448 1.000000e+00   5 146144350 146144471 122 - 0.128 0.130 0.019
ENSG00000133706 E037 26.2498293 0.0017337505 6.436711e-02 2.862734e-01 5 146144472 146144537 66 - 1.458 1.341 -0.405
ENSG00000133706 E038 1.1939406 0.0104224998 8.371457e-01 9.458087e-01 5 146144538 146144623 86 - 0.343 0.311 -0.204
ENSG00000133706 E039 17.5075397 0.0007868586 2.092767e-02 1.482079e-01 5 146144624 146144662 39 - 1.307 1.132 -0.619
ENSG00000133706 E040 21.3801262 0.0007561799 9.199526e-02 3.484098e-01 5 146144663 146144709 47 - 1.372 1.257 -0.400
ENSG00000133706 E041 9.9376834 0.0583315031 3.894410e-02 2.154157e-01 5 146144710 146146511 1802 - 0.906 1.174 0.983
ENSG00000133706 E042 7.4078405 0.0021089547 1.245536e-01 4.088832e-01 5 146146512 146148199 1688 - 0.846 1.003 0.590
ENSG00000133706 E043 3.6287486 0.0090244954 4.388323e-01 7.399919e-01 5 146148200 146149551 1352 - 0.612 0.714 0.434
ENSG00000133706 E044 1.0272273 0.0109505283 1.731166e-02 1.322310e-01 5 146149552 146149621 70 - 0.406 0.000 -12.907
ENSG00000133706 E045 19.1128453 0.0007121977 8.201460e-02 3.275278e-01 5 146149622 146149657 36 - 1.328 1.204 -0.438
ENSG00000133706 E046 21.3894064 0.0006427458 9.127275e-02 3.469606e-01 5 146149658 146149699 42 - 1.372 1.257 -0.400
ENSG00000133706 E047 0.1141751 0.0111838427 1.000000e+00   5 146151500 146151861 362 - 0.069 0.000 -9.918
ENSG00000133706 E048 30.9601656 0.0004510109 1.399796e-02 1.156210e-01 5 146151862 146152002 141 - 1.534 1.393 -0.486
ENSG00000133706 E049 13.5615332 0.0009741251 2.531988e-01 5.802585e-01 5 146153174 146153227 54 - 1.179 1.085 -0.339
ENSG00000133706 E050 17.4984936 0.0008719421 2.439391e-01 5.702255e-01 5 146153734 146153810 77 - 1.280 1.194 -0.303
ENSG00000133706 E051 19.2543778 0.0017762836 7.139257e-01 8.939019e-01 5 146153893 146153980 88 - 1.299 1.274 -0.090
ENSG00000133706 E052 0.0000000       5 146157397 146157402 6 -      
ENSG00000133706 E053 35.7177205 0.0005733345 1.023744e-01 3.685755e-01 5 146157403 146157628 226 - 1.578 1.491 -0.296
ENSG00000133706 E054 13.9316956 0.0219579922 4.495780e-01 7.476404e-01 5 146157728 146157795 68 - 1.184 1.109 -0.269
ENSG00000133706 E055 14.6397197 0.0083725039 7.754121e-01 9.219775e-01 5 146159407 146159470 64 - 1.169 1.194 0.089
ENSG00000133706 E056 17.7586525 0.0018464483 3.642212e-01 6.833380e-01 5 146160374 146160486 113 - 1.280 1.213 -0.236
ENSG00000133706 E057 0.6852154 0.0233464522 7.113223e-02 3.026712e-01 5 146162528 146164309 1782 - 0.308 0.000 -12.367
ENSG00000133706 E058 22.0488764 0.0005915557 3.200998e-02 1.913151e-01 5 146164310 146164471 162 - 1.393 1.249 -0.505
ENSG00000133706 E059 9.5088773 0.0013700807 2.859091e-01 6.134027e-01 5 146168128 146168147 20 - 1.040 0.938 -0.380
ENSG00000133706 E060 18.5084111 0.0007154522 6.735956e-02 2.939334e-01 5 146168148 146168265 118 - 1.318 1.184 -0.469
ENSG00000133706 E061 14.3845678 0.0009376586 8.241850e-03 8.178072e-02 5 146171910 146171990 81 - 1.239 1.017 -0.796
ENSG00000133706 E062 16.9907632 0.0007713937 1.362148e-01 4.275973e-01 5 146172687 146172774 88 - 1.276 1.164 -0.396
ENSG00000133706 E063 21.5951713 0.0058227665 8.286679e-01 9.422331e-01 5 146177547 146177665 119 - 1.332 1.347 0.055
ENSG00000133706 E064 0.3761841 0.0165614904 2.398787e-01   5 146181012 146181187 176 - 0.069 0.230 2.019
ENSG00000133706 E065 0.6058189 0.1880254693 7.737729e-01   5 146182140 146182475 336 - 0.181 0.230 0.434
ENSG00000133706 E066 13.3685668 0.0010379558 5.418438e-01 8.061071e-01 5 146182488 146182561 74 - 1.159 1.109 -0.179
ENSG00000133706 E067 6.5608052 0.0051960166 1.282548e-02 1.090238e-01 5 146182562 146182621 60 - 0.950 0.652 -1.183
ENSG00000133706 E068 2.0087808 0.0071480089 3.946388e-01 7.075243e-01 5 146182622 146182696 75 - 0.510 0.379 -0.682

Help

Please Click HERE to learn more details about the results from DEXseq.