ENSG00000133739

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360375 ENSG00000133739 No_inf pgwt_inf LRRCC1 protein_coding protein_coding 5.837186 7.156025 4.575333 0.2059553 0.5252421 -0.6441466 1.4476789 1.9504596 0.6338778 0.5851959 0.2110786 -1.6063330 0.250375 0.277250 0.144225 -0.133025 0.99284725 0.01069326 FALSE TRUE
ENST00000517875 ENSG00000133739 No_inf pgwt_inf LRRCC1 protein_coding nonsense_mediated_decay 5.837186 7.156025 4.575333 0.2059553 0.5252421 -0.6441466 0.3610907 0.8420800 0.2411922 0.8420800 0.2411922 -1.7621975 0.059100 0.108550 0.068750 -0.039800 1.00000000 0.01069326 FALSE TRUE
ENST00000522567 ENSG00000133739 No_inf pgwt_inf LRRCC1 protein_coding nonsense_mediated_decay 5.837186 7.156025 4.575333 0.2059553 0.5252421 -0.6441466 0.8440286 0.0000000 1.1200499 0.0000000 0.2046655 6.8202427 0.163450 0.000000 0.256375 0.256375 0.01069326 0.01069326 FALSE TRUE
MSTRG.27860.1 ENSG00000133739 No_inf pgwt_inf LRRCC1 protein_coding   5.837186 7.156025 4.575333 0.2059553 0.5252421 -0.6441466 1.1443746 0.7986883 1.3981327 0.5408779 0.8511501 0.8001277 0.197100 0.114000 0.265875 0.151875 0.99284725 0.01069326 FALSE TRUE
MSTRG.27860.8 ENSG00000133739 No_inf pgwt_inf LRRCC1 protein_coding   5.837186 7.156025 4.575333 0.2059553 0.5252421 -0.6441466 0.4130026 0.0000000 0.3616857 0.0000000 0.3616857 5.2160113 0.069200 0.000000 0.060050 0.060050 0.99284725 0.01069326 FALSE FALSE
MSTRG.27860.9 ENSG00000133739 No_inf pgwt_inf LRRCC1 protein_coding   5.837186 7.156025 4.575333 0.2059553 0.5252421 -0.6441466 1.5606630 3.4732970 0.7128508 0.7618474 0.4168803 -2.2686836 0.248250 0.487225 0.180125 -0.307100 0.92646974 0.01069326 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000133739 E001 0.0000000       8 85107209 85107214 6 +      
ENSG00000133739 E002 0.2277562 0.015336483 0.09964142   8 85107215 85107237 23 + 0.220 0.000 -11.768
ENSG00000133739 E003 2.3230879 0.010840404 0.14628377 0.44228975 8 85107238 85107399 162 + 0.633 0.421 -1.007
ENSG00000133739 E004 0.0000000       8 85107400 85107718 319 +      
ENSG00000133739 E005 0.2617264 0.236149589 0.57692443   8 85108662 85109594 933 + 0.000 0.135 9.856
ENSG00000133739 E006 2.7853144 0.006290050 0.38391318 0.69951037 8 85109595 85109800 206 + 0.474 0.592 0.560
ENSG00000133739 E007 2.1739797 0.007381515 0.03284637 0.19415236 8 85110115 85110180 66 + 0.665 0.357 -1.508
ENSG00000133739 E008 1.3232668 0.011170956 0.06752656 0.29434337 8 85112932 85112945 14 + 0.519 0.238 -1.663
ENSG00000133739 E009 3.8900771 0.051383187 0.05741329 0.26820153 8 85112946 85113099 154 + 0.840 0.550 -1.218
ENSG00000133739 E010 0.4737248 0.016116078 0.11758723   8 85114312 85114355 44 + 0.298 0.073 -2.440
ENSG00000133739 E011 5.9743834 0.002800473 0.61184043 0.84350511 8 85115100 85115275 176 + 0.861 0.798 -0.245
ENSG00000133739 E012 5.0121501 0.002839438 0.88781279 0.96527321 8 85115375 85115584 210 + 0.749 0.758 0.038
ENSG00000133739 E013 7.6326527 0.018976441 0.99219594 1.00000000 8 85123413 85123606 194 + 0.916 0.908 -0.029
ENSG00000133739 E014 8.6130393 0.001977463 0.77951569 0.92360883 8 85124792 85124939 148 + 0.981 0.946 -0.130
ENSG00000133739 E015 5.1264666 0.034721191 0.92248751 0.97797998 8 85126689 85126837 149 + 0.774 0.758 -0.062
ENSG00000133739 E016 6.8154530 0.002250056 0.31125977 0.63739701 8 85129175 85129379 205 + 0.797 0.899 0.392
ENSG00000133739 E017 6.0257998 0.102977285 0.21664724 0.53962066 8 85129919 85130058 140 + 0.950 0.744 -0.797
ENSG00000133739 E018 11.0056085 0.002509167 0.95122973 0.98781898 8 85131760 85131961 202 + 1.062 1.049 -0.048
ENSG00000133739 E019 9.6646546 0.001502435 0.66644454 0.87058998 8 85134847 85135032 186 + 0.981 1.012 0.116
ENSG00000133739 E020 9.8751424 0.103421439 0.90383000 0.97154801 8 85135789 85135963 175 + 1.023 1.004 -0.069
ENSG00000133739 E021 9.3474409 0.012169621 0.65846194 0.86669437 8 85137464 85137627 164 + 1.023 0.972 -0.190
ENSG00000133739 E022 12.0751356 0.001223354 0.01053456 0.09594063 8 85138035 85138243 209 + 0.933 1.149 0.791
ENSG00000133739 E023 9.4741591 0.013131984 0.72254266 0.89803997 8 85138338 85138475 138 + 1.023 0.980 -0.159
ENSG00000133739 E024 8.8782702 0.001717604 0.05897557 0.27283459 8 85141382 85141517 136 + 0.841 1.020 0.675
ENSG00000133739 E025 11.1282107 0.005533475 0.13208113 0.42119653 8 85145389 85146198 810 + 0.965 1.096 0.478

Help

Please Click HERE to learn more details about the results from DEXseq.