ENSG00000133805

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000396553 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding protein_coding 153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 26.220671 1.632393 36.381753 0.9696636 3.6214242 4.4697405 0.14365000 0.019125 0.192000 0.172875 0.26471523 0.03327968 FALSE TRUE
ENST00000529744 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding nonsense_mediated_decay 153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 5.342837 7.762172 0.697034 1.6275233 0.6970340 -3.4584663 0.04485833 0.090125 0.003675 -0.086450 0.03327968 0.03327968 FALSE TRUE
ENST00000529834 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding nonsense_mediated_decay 153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 9.469698 3.767022 11.765454 1.8224861 1.6049927 1.6404618 0.05870833 0.045025 0.061975 0.016950 0.99284725 0.03327968 TRUE TRUE
ENST00000530864 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding protein_coding_CDS_not_defined 153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 29.270066 12.266999 37.106970 4.3019868 2.0985766 1.5961210 0.18006667 0.138775 0.195575 0.056800 0.99284725 0.03327968 FALSE FALSE
MSTRG.4412.12 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding   153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 9.652023 7.603310 15.014386 1.3259842 1.2667520 0.9807102 0.06790000 0.090100 0.079250 -0.010850 1.00000000 0.03327968 TRUE TRUE
MSTRG.4412.19 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding   153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 22.265905 13.465948 27.053383 1.9791873 1.2990908 1.0059554 0.14868333 0.161800 0.142625 -0.019175 1.00000000 0.03327968 FALSE TRUE
MSTRG.4412.22 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding   153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 9.203585 6.414860 11.983387 0.3460514 0.4557291 0.9005022 0.06315000 0.076125 0.063175 -0.012950 0.99284725 0.03327968 FALSE TRUE
MSTRG.4412.25 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding   153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 9.921185 6.444241 11.770686 1.0703152 1.3044050 0.8681042 0.06725000 0.077450 0.062150 -0.015300 0.99516766 0.03327968 FALSE TRUE
MSTRG.4412.27 ENSG00000133805 No_inf pgwt_inf AMPD3 protein_coding   153.0608 84.73455 189.6532 3.665253 0.6599063 1.162247 11.721525 10.698803 15.279470 0.8119999 1.3090490 0.5137412 0.08613333 0.128150 0.080575 -0.047575 0.99284725 0.03327968 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000133805 E001 0.1308632 1.221044e-02 2.255480e-01   11 10308313 10308673 361 + 0.000 0.135 10.271
ENSG00000133805 E002 0.0000000       11 10317671 10317768 98 +      
ENSG00000133805 E003 0.1308632 1.221044e-02 2.255480e-01   11 10330570 10330659 90 + 0.000 0.135 12.352
ENSG00000133805 E004 0.0000000       11 10330660 10330709 50 +      
ENSG00000133805 E005 0.0000000       11 10357273 10357391 119 +      
ENSG00000133805 E006 0.0000000       11 10392282 10392405 124 +      
ENSG00000133805 E007 0.0000000       11 10408368 10408505 138 +      
ENSG00000133805 E008 0.1315150 1.228238e-02 2.255670e-01   11 10410757 10410838 82 + 0.000 0.135 12.351
ENSG00000133805 E009 4.2520049 3.251546e-03 1.498582e-01 4.478620e-01 11 10450321 10450496 176 + 0.632 0.811 0.735
ENSG00000133805 E010 2.3509071 8.559138e-03 2.705227e-01 5.984613e-01 11 10450497 10450515 19 + 0.560 0.391 -0.850
ENSG00000133805 E011 3.7429886 4.046346e-03 3.776353e-01 6.949957e-01 11 10450516 10450680 165 + 0.615 0.731 0.487
ENSG00000133805 E012 1.3580969 9.541235e-03 1.127710e-01 3.883118e-01 11 10450681 10450699 19 + 0.260 0.504 1.413
ENSG00000133805 E013 1.2092364 1.541672e-02 5.597256e-01 8.159636e-01 11 10450700 10450706 7 + 0.298 0.391 0.565
ENSG00000133805 E014 2.8306064 5.337140e-03 3.915296e-02 2.160576e-01 11 10450707 10450764 58 + 0.448 0.731 1.276
ENSG00000133805 E015 5.0576476 4.058826e-02 1.037444e-02 9.485658e-02 11 10450765 10450941 177 + 0.615 0.955 1.362
ENSG00000133805 E016 3.1568497 7.858622e-02 3.402543e-01 6.622211e-01 11 10450942 10451043 102 + 0.540 0.700 0.703
ENSG00000133805 E017 0.8507129 1.306747e-02 5.189316e-01 7.919037e-01 11 10455264 10455281 18 + 0.219 0.321 0.735
ENSG00000133805 E018 4.7662270 2.878597e-03 4.787172e-03 5.642557e-02 11 10455282 10455339 58 + 0.840 0.451 -1.698
ENSG00000133805 E019 7.7683432 1.782399e-03 6.586693e-05 2.093779e-03 11 10455340 10455406 67 + 1.036 0.551 -1.949
ENSG00000133805 E020 7.4946480 2.204026e-03 1.195016e-02 1.043226e-01 11 10455407 10455448 42 + 0.987 0.700 -1.118
ENSG00000133805 E021 14.1470345 1.179024e-03 6.446121e-02 2.864547e-01 11 10456042 10456185 144 + 1.103 1.250 0.524
ENSG00000133805 E022 8.7286597 1.739789e-03 9.455119e-01 9.862932e-01 11 10456186 10456210 25 + 0.965 0.973 0.030
ENSG00000133805 E023 27.1586432 3.477620e-03 7.593448e-01 9.146011e-01 11 10456211 10456402 192 + 1.420 1.441 0.073
ENSG00000133805 E024 8.5657073 2.587659e-02 1.181458e-04 3.377431e-03 11 10457014 10457484 471 + 0.761 1.193 1.614
ENSG00000133805 E025 12.6219315 4.189773e-03 8.359306e-07 4.865813e-05 11 10459228 10459786 559 + 0.924 1.338 1.491
ENSG00000133805 E026 7.4020912 2.325362e-02 2.082414e-03 3.130757e-02 11 10461140 10461424 285 + 0.748 1.103 1.343
ENSG00000133805 E027 75.3566319 1.898931e-04 9.883666e-03 9.192086e-02 11 10461515 10461740 226 + 1.891 1.794 -0.325
ENSG00000133805 E028 100.9131189 1.537600e-04 9.223341e-04 1.690129e-02 11 10478526 10478730 205 + 2.019 1.912 -0.361
ENSG00000133805 E029 0.2277562 1.534858e-02 6.728688e-01   11 10481883 10482062 180 + 0.123 0.000 -12.685
ENSG00000133805 E030 91.6676984 4.251571e-04 1.243126e-02 1.070799e-01 11 10482063 10482225 163 + 1.972 1.886 -0.289
ENSG00000133805 E031 49.6521712 6.596623e-04 3.058917e-01 6.326823e-01 11 10484820 10484905 86 + 1.697 1.651 -0.157
ENSG00000133805 E032 68.8330471 1.953036e-04 2.002910e-03 3.044859e-02 11 10484906 10485039 134 + 1.859 1.737 -0.412
ENSG00000133805 E033 2.1062752 7.179444e-03 1.654364e-01 4.712070e-01 11 10486375 10486415 41 + 0.540 0.321 -1.172
ENSG00000133805 E034 77.7292598 1.799953e-04 8.115375e-03 8.099507e-02 11 10487235 10487364 130 + 1.904 1.807 -0.328
ENSG00000133805 E035 42.0414205 3.156084e-04 3.635653e-01 6.830108e-01 11 10493349 10493366 18 + 1.626 1.582 -0.149
ENSG00000133805 E036 75.3373918 2.082718e-04 9.280417e-04 1.697658e-02 11 10493367 10493480 114 + 1.899 1.774 -0.423
ENSG00000133805 E037 50.3506807 2.754833e-04 9.795070e-03 9.146545e-02 11 10493481 10493543 63 + 1.725 1.606 -0.403
ENSG00000133805 E038 0.6048832 2.091095e-02 6.779102e-01   11 10493544 10493702 159 + 0.174 0.238 0.565
ENSG00000133805 E039 37.0790498 4.153788e-04 2.276379e-02 1.565538e-01 11 10494899 10494907 9 + 1.596 1.474 -0.416
ENSG00000133805 E040 119.1314207 1.426736e-04 4.239829e-03 5.189660e-02 11 10494908 10495030 123 + 2.084 1.999 -0.283
ENSG00000133805 E041 179.4247855 9.791867e-05 2.399704e-04 5.952837e-03 11 10495570 10495733 164 + 2.261 2.173 -0.294
ENSG00000133805 E042 3.7126306 1.092727e-02 8.950760e-01 9.684738e-01 11 10496761 10496811 51 + 0.648 0.667 0.080
ENSG00000133805 E043 121.4012091 4.040239e-04 2.371046e-02 1.601530e-01 11 10496812 10496938 127 + 2.087 2.019 -0.225
ENSG00000133805 E044 17.3152973 1.243068e-02 4.417116e-02 2.308383e-01 11 10496939 10497437 499 + 1.175 1.345 0.599
ENSG00000133805 E045 48.1692572 5.126051e-03 7.856983e-03 7.913055e-02 11 10497590 10498281 692 + 1.615 1.757 0.481
ENSG00000133805 E046 4.8299715 1.773173e-02 2.229610e-01 5.469008e-01 11 10498282 10498309 28 + 0.796 0.632 -0.680
ENSG00000133805 E047 11.6695221 8.474555e-03 3.341204e-01 6.572711e-01 11 10498310 10498400 91 + 1.049 1.139 0.325
ENSG00000133805 E048 9.4291279 6.513198e-03 8.929657e-01 9.676059e-01 11 10498401 10498436 36 + 1.002 0.989 -0.046
ENSG00000133805 E049 69.5644890 4.737673e-04 1.519687e-04 4.113926e-03 11 10498437 10499244 808 + 1.771 1.916 0.488
ENSG00000133805 E050 17.8804874 1.110689e-02 7.365918e-02 3.082352e-01 11 10499245 10499356 112 + 1.198 1.345 0.517
ENSG00000133805 E051 91.6601219 1.602567e-04 1.624514e-12 2.449970e-10 11 10499357 10500085 729 + 1.852 2.080 0.765
ENSG00000133805 E052 117.0516859 1.376277e-04 8.285825e-02 3.289032e-01 11 10500086 10500184 99 + 2.031 2.083 0.175
ENSG00000133805 E053 83.6420021 1.781588e-04 5.469656e-01 8.090561e-01 11 10500185 10500249 65 + 1.897 1.919 0.075
ENSG00000133805 E054 127.8114910 1.261170e-04 2.948318e-01 6.230876e-01 11 10501470 10501590 121 + 2.097 2.068 -0.095
ENSG00000133805 E055 105.0774398 1.919898e-04 7.735201e-01 9.211253e-01 11 10502721 10502782 62 + 2.005 1.998 -0.025
ENSG00000133805 E056 136.0366549 1.203625e-03 1.543252e-01 4.547098e-01 11 10502783 10502894 112 + 2.128 2.085 -0.143
ENSG00000133805 E057 64.4953356 2.218484e-04 6.806262e-02 2.957209e-01 11 10502895 10503787 893 + 1.767 1.840 0.246
ENSG00000133805 E058 63.3557151 6.011076e-04 7.999369e-02 3.229803e-01 11 10504549 10504579 31 + 1.809 1.737 -0.242
ENSG00000133805 E059 91.3420877 1.855004e-04 8.059454e-01 9.335894e-01 11 10504580 10504659 80 + 1.945 1.938 -0.023
ENSG00000133805 E060 1036.3341706 3.281676e-05 9.644711e-06 4.119060e-04 11 10505708 10507839 2132 + 2.979 3.018 0.129
ENSG00000133805 E061 4.2690326 4.760288e-03 7.649612e-02 3.146744e-01 11 10507840 10508088 249 + 0.615 0.835 0.902

Help

Please Click HERE to learn more details about the results from DEXseq.