ENSG00000134759

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358232 ENSG00000134759 No_inf pgwt_inf ELP2 protein_coding protein_coding 52.84288 37.99307 55.34619 2.772307 4.154501 0.5426286 3.060787 2.138566 3.677397 1.237425 0.4841366 0.7792287 0.06022500 0.059025 0.068350 0.009325 9.928472e-01 1.505308e-05 FALSE TRUE
ENST00000535093 ENSG00000134759 No_inf pgwt_inf ELP2 protein_coding protein_coding_CDS_not_defined 52.84288 37.99307 55.34619 2.772307 4.154501 0.5426286 10.817777 6.337905 10.906124 1.324113 2.6778805 0.7821082 0.19894167 0.170450 0.191700 0.021250 1.000000e+00 1.505308e-05 FALSE FALSE
ENST00000540135 ENSG00000134759 No_inf pgwt_inf ELP2 protein_coding protein_coding_CDS_not_defined 52.84288 37.99307 55.34619 2.772307 4.154501 0.5426286 4.482226 0.000000 9.254230 0.000000 1.2981466 9.8555273 0.07844167 0.000000 0.169600 0.169600 1.505308e-05 1.505308e-05 FALSE TRUE
ENST00000542050 ENSG00000134759 No_inf pgwt_inf ELP2 protein_coding protein_coding_CDS_not_defined 52.84288 37.99307 55.34619 2.772307 4.154501 0.5426286 12.303626 11.461824 9.382106 2.481516 0.6903019 -0.2885743 0.23671667 0.294025 0.172575 -0.121450 9.928472e-01 1.505308e-05 FALSE TRUE
ENST00000543127 ENSG00000134759 No_inf pgwt_inf ELP2 protein_coding protein_coding 52.84288 37.99307 55.34619 2.772307 4.154501 0.5426286 1.789089 2.703985 0.000000 2.703985 0.0000000 -8.0842691 0.03338333 0.060800 0.000000 -0.060800 9.928472e-01 1.505308e-05   FALSE
ENST00000543439 ENSG00000134759 No_inf pgwt_inf ELP2 protein_coding protein_coding_CDS_not_defined 52.84288 37.99307 55.34619 2.772307 4.154501 0.5426286 4.277911 2.001955 6.542801 1.247195 1.2075572 1.7035140 0.07894167 0.052075 0.118125 0.066050 9.680109e-01 1.505308e-05 FALSE FALSE
ENST00000543861 ENSG00000134759 No_inf pgwt_inf ELP2 protein_coding protein_coding_CDS_not_defined 52.84288 37.99307 55.34619 2.772307 4.154501 0.5426286 9.064327 4.061631 12.365120 1.574756 2.3184914 1.6037639 0.16685000 0.113950 0.221550 0.107600 9.928472e-01 1.505308e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000134759 E001 0.1138060 0.0112091393 5.676747e-01   18 36129444 36129497 54 + 0.093 0.000 -10.603
ENSG00000134759 E002 0.0000000       18 36129880 36129890 11 +      
ENSG00000134759 E003 0.0000000       18 36129891 36129893 3 +      
ENSG00000134759 E004 0.0000000       18 36129894 36129894 1 +      
ENSG00000134759 E005 0.0000000       18 36129895 36129897 3 +      
ENSG00000134759 E006 0.0000000       18 36129898 36129898 1 +      
ENSG00000134759 E007 0.0000000       18 36129899 36129900 2 +      
ENSG00000134759 E008 0.0000000       18 36129901 36129901 1 +      
ENSG00000134759 E009 0.0000000       18 36129902 36129902 1 +      
ENSG00000134759 E010 0.3763283 0.0166543681 5.504717e-01   18 36129903 36129916 14 + 0.093 0.177 1.082
ENSG00000134759 E011 0.5074772 0.0153398199 2.936950e-01   18 36129917 36129919 3 + 0.093 0.244 1.666
ENSG00000134759 E012 0.5074772 0.0153398199 2.936950e-01   18 36129920 36129922 3 + 0.093 0.244 1.666
ENSG00000134759 E013 0.7533142 0.0133676439 3.771454e-01 6.945997e-01 18 36129923 36129923 1 + 0.169 0.303 1.082
ENSG00000134759 E014 0.7533142 0.0133676439 3.771454e-01 6.945997e-01 18 36129924 36129924 1 + 0.169 0.303 1.082
ENSG00000134759 E015 7.9282520 0.0018786452 2.465227e-02 1.640111e-01 18 36129925 36130071 147 + 1.051 0.832 -0.821
ENSG00000134759 E016 7.5042595 0.0020255500 1.914680e-01 5.064915e-01 18 36133238 36133316 79 + 0.992 0.863 -0.484
ENSG00000134759 E017 8.4234419 0.0018329333 7.066928e-01 8.905121e-01 18 36136307 36136377 71 + 0.992 0.957 -0.128
ENSG00000134759 E018 0.1315150 0.0123136493 5.097781e-01   18 36136378 36136632 255 + 0.000 0.098 12.543
ENSG00000134759 E019 0.3769858 0.0166734973 5.504037e-01   18 36137174 36137183 10 + 0.093 0.177 1.082
ENSG00000134759 E020 0.7550303 0.0511226125 3.879198e-01 7.022266e-01 18 36137184 36137235 52 + 0.169 0.303 1.081
ENSG00000134759 E021 0.2620121 0.0160336586 2.245563e-01   18 36138095 36138269 175 + 0.000 0.177 13.472
ENSG00000134759 E022 6.3280591 0.0035466658 5.274453e-01 7.972427e-01 18 36138270 36138294 25 + 0.898 0.832 -0.253
ENSG00000134759 E023 11.5284397 0.0018963434 2.047855e-01 5.243701e-01 18 36138295 36138426 132 + 1.149 1.044 -0.378
ENSG00000134759 E024 0.8842354 0.0651801241 2.476371e-01 5.744652e-01 18 36138427 36138641 215 + 0.169 0.354 1.404
ENSG00000134759 E025 4.1540817 0.0043876655 8.548065e-01 9.528470e-01 18 36138795 36138806 12 + 0.723 0.702 -0.088
ENSG00000134759 E026 6.5715807 0.0029406619 5.412491e-01 8.056514e-01 18 36138807 36138872 66 + 0.911 0.848 -0.240
ENSG00000134759 E027 1.7679021 0.0079080301 8.729193e-02 3.387412e-01 18 36139419 36139613 195 + 0.290 0.546 1.403
ENSG00000134759 E028 0.3940400 0.0159624298 9.296207e-02   18 36139662 36139760 99 + 0.000 0.244 14.009
ENSG00000134759 E029 8.4392967 0.0024767461 8.905506e-01 9.664076e-01 18 36141137 36141201 65 + 0.981 0.969 -0.044
ENSG00000134759 E030 0.1308632 0.0121676448 5.099988e-01   18 36141373 36141422 50 + 0.000 0.098 12.543
ENSG00000134759 E031 10.4479629 0.0014408167 2.987969e-01 6.262855e-01 18 36142281 36142347 67 + 1.103 1.014 -0.324
ENSG00000134759 E032 0.0000000       18 36142348 36142349 2 +      
ENSG00000134759 E033 5.1613172 0.0937759043 2.236465e-01 5.478771e-01 18 36142826 36142829 4 + 0.884 0.679 -0.818
ENSG00000134759 E034 16.4594265 0.0026246443 6.105178e-02 2.780776e-01 18 36142830 36142966 137 + 1.307 1.172 -0.477
ENSG00000134759 E035 11.4276377 0.0052016742 3.543459e-01 6.742281e-01 18 36144939 36145034 96 + 1.134 1.054 -0.289
ENSG00000134759 E036 0.0000000       18 36145035 36145358 324 +      
ENSG00000134759 E037 11.0686852 0.0012916660 3.717053e-01 6.899505e-01 18 36145948 36146048 101 + 1.119 1.044 -0.269
ENSG00000134759 E038 16.6984764 0.0208628271 1.015142e-01 3.671220e-01 18 36146250 36146381 132 + 1.317 1.172 -0.512
ENSG00000134759 E039 13.6454216 0.0045832461 4.195227e-01 7.258468e-01 18 36154850 36154930 81 + 1.197 1.133 -0.229
ENSG00000134759 E040 13.0697778 0.0010864294 6.919555e-01 8.828598e-01 18 36154931 36154999 69 + 1.163 1.133 -0.108
ENSG00000134759 E041 22.2748469 0.0010390249 4.484924e-02 2.324439e-01 18 36156466 36156654 189 + 1.297 1.422 0.436
ENSG00000134759 E042 0.0000000       18 36158503 36158614 112 +      
ENSG00000134759 E043 12.5308127 0.0063562003 6.667511e-01 8.706985e-01 18 36158835 36158904 70 + 1.111 1.149 0.138
ENSG00000134759 E044 8.9157098 0.0026421393 7.264634e-01 8.999725e-01 18 36159735 36159757 23 + 1.012 0.981 -0.116
ENSG00000134759 E045 16.2109216 0.0008470866 4.138681e-01 7.214560e-01 18 36159758 36159830 73 + 1.264 1.207 -0.201
ENSG00000134759 E046 0.2620121 0.0160336586 2.245563e-01   18 36159957 36159957 1 + 0.000 0.177 13.472
ENSG00000134759 E047 12.2485553 0.0011472394 1.554319e-01 4.564759e-01 18 36159958 36160015 58 + 1.177 1.064 -0.409
ENSG00000134759 E048 13.9180768 0.0013259771 6.396961e-02 2.852731e-01 18 36160932 36161004 73 + 1.241 1.100 -0.503
ENSG00000134759 E049 35.5019680 0.0027494322 9.095055e-01 9.732707e-01 18 36164475 36164667 193 + 1.565 1.559 -0.018
ENSG00000134759 E050 6.1232490 0.0042557994 4.350676e-02 2.291952e-01 18 36164668 36165225 558 + 0.723 0.945 0.866
ENSG00000134759 E051 0.6573636 0.0433759897 1.942576e-02 1.414035e-01 18 36166889 36166965 77 + 0.000 0.354 14.578
ENSG00000134759 E052 1.7186317 0.0089702095 9.197027e-01 9.767321e-01 18 36166966 36167047 82 + 0.426 0.441 0.082
ENSG00000134759 E053 1.9815808 0.1204918822 6.345441e-01 8.544175e-01 18 36167048 36167100 53 + 0.426 0.514 0.445
ENSG00000134759 E054 19.7239459 0.0006983347 2.806069e-01 6.088700e-01 18 36167101 36167152 52 + 1.351 1.282 -0.240
ENSG00000134759 E055 10.2665085 0.0013939394 6.942955e-02 2.987419e-01 18 36167153 36167155 3 + 1.126 0.969 -0.575
ENSG00000134759 E056 19.4466922 0.0008939751 1.606068e-01 4.635695e-01 18 36167156 36167222 67 + 1.355 1.264 -0.318
ENSG00000134759 E057 1.9472321 0.0122591783 7.008014e-01 8.873807e-01 18 36169936 36170062 127 + 0.497 0.441 -0.281
ENSG00000134759 E058 30.0569206 0.0007084677 5.483635e-01 8.101242e-01 18 36170063 36170196 134 + 1.508 1.477 -0.106
ENSG00000134759 E059 1.7859140 0.0087697125 2.295853e-02 1.572637e-01 18 36170879 36171046 168 + 0.234 0.576 1.956
ENSG00000134759 E060 26.3356050 0.0005715108 4.559012e-02 2.347427e-01 18 36171047 36171160 114 + 1.373 1.487 0.394
ENSG00000134759 E061 78.4798116 0.0002095052 1.826766e-09 1.785925e-07 18 36174485 36180557 6073 + 1.789 1.982 0.651

Help

Please Click HERE to learn more details about the results from DEXseq.