ENSG00000134769

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000283365 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding protein_coding 13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 1.5154560 2.799767 0.8050656 1.1657759 0.8050656 -1.7854624 0.10378333 0.175725 0.076575 -0.099150 0.9626630780 0.0001854489 FALSE TRUE
ENST00000592449 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding protein_coding_CDS_not_defined 13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 2.0164891 3.162911 0.9757693 1.4106945 0.6601044 -1.6864851 0.14242500 0.196075 0.093025 -0.103050 0.9928472467 0.0001854489   FALSE
ENST00000595022 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding protein_coding 13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 0.2721174 0.000000 0.8163521 0.0000000 0.8163521 6.3686848 0.02609167 0.000000 0.078275 0.078275 0.9928472467 0.0001854489 FALSE TRUE
ENST00000681470 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding protein_coding 13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 1.0574261 0.000000 2.2385880 0.0000000 1.0213027 7.8128755 0.10672500 0.000000 0.234175 0.234175 0.2534915092 0.0001854489 FALSE TRUE
ENST00000681759 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding protein_coding 13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 0.9853868 1.964658 0.0000000 0.7271321 0.0000000 -7.6254590 0.06186667 0.119625 0.000000 -0.119625 0.3970068072 0.0001854489 FALSE TRUE
ENST00000683379 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding protein_coding 13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 0.7472181 1.224741 0.0000000 0.9391202 0.0000000 -6.9480652 0.05765833 0.087075 0.000000 -0.087075 0.9928472467 0.0001854489 FALSE TRUE
MSTRG.13837.1 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding   13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 0.9914229 1.059577 1.2256460 0.5452733 0.1595556 0.2082247 0.08028333 0.069375 0.122400 0.053025 0.9928472467 0.0001854489 FALSE TRUE
MSTRG.13837.12 ENSG00000134769 No_inf pgwt_inf DTNA protein_coding   13.13984 16.03487 9.966978 1.108466 0.2969229 -0.6854376 1.4765856 0.000000 2.4527905 0.0000000 0.3626124 7.9441501 0.13455833 0.000000 0.249150 0.249150 0.0001854489 0.0001854489 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000134769 E001 2.7006297 0.0053931578 4.052018e-01 0.715087339 18 34492974 34493290 317 + 0.624 0.513 -0.508
ENSG00000134769 E002 0.7358878 0.0143350255 6.640042e-01 0.869216246 18 34493291 34493303 13 + 0.273 0.208 -0.507
ENSG00000134769 E003 0.8674028 0.0137196060 9.256568e-01 0.979155368 18 34493304 34493313 10 + 0.273 0.260 -0.092
ENSG00000134769 E004 0.8674028 0.0137196060 9.256568e-01 0.979155368 18 34493314 34493316 3 + 0.273 0.260 -0.092
ENSG00000134769 E005 0.9990646 0.0141154506 8.369620e-01 0.945721986 18 34493317 34493330 14 + 0.273 0.307 0.230
ENSG00000134769 E006 1.2437337 0.0125390331 9.434653e-01 0.985710415 18 34493331 34493355 25 + 0.336 0.349 0.077
ENSG00000134769 E007 0.8672639 0.0149133210 9.260372e-01 0.979275094 18 34493356 34493360 5 + 0.273 0.260 -0.092
ENSG00000134769 E008 0.9987789 0.0135957008 8.375665e-01 0.945891287 18 34493361 34493370 10 + 0.273 0.307 0.229
ENSG00000134769 E009 0.9021716 0.0124602982 1.285081e-01 0.415730048 18 34493371 34493388 18 + 0.111 0.349 2.077
ENSG00000134769 E010 1.2793766 0.0110588617 1.603133e-01 0.463206341 18 34493389 34493409 21 + 0.200 0.422 1.493
ENSG00000134769 E011 1.5077676 0.0097177469 5.865826e-01 0.830404106 18 34493410 34493429 20 + 0.336 0.422 0.492
ENSG00000134769 E012 3.4892823 0.0048130861 8.494865e-01 0.950586855 18 34493430 34493514 85 + 0.624 0.652 0.121
ENSG00000134769 E013 0.2623781 0.0160363108 3.921270e-01   18 34493903 34493914 12 + 0.000 0.149 12.900
ENSG00000134769 E014 0.0000000       18 34493915 34493958 44 +      
ENSG00000134769 E015 0.1316618 0.0123366444 7.728590e-01   18 34493959 34493981 23 + 0.000 0.081 11.990
ENSG00000134769 E016 0.2458369 0.0162784954 7.799501e-01   18 34493982 34494021 40 + 0.111 0.081 -0.508
ENSG00000134769 E017 0.0000000       18 34494529 34494589 61 +      
ENSG00000134769 E018 0.2622978 0.3153542896 4.668185e-01   18 34496547 34496835 289 + 0.000 0.149 12.633
ENSG00000134769 E019 0.0000000       18 34504043 34504157 115 +      
ENSG00000134769 E020 0.4917146 0.1016824747 7.345536e-01   18 34513515 34513937 423 + 0.200 0.149 -0.508
ENSG00000134769 E021 0.0000000       18 34557979 34558135 157 +      
ENSG00000134769 E022 0.0000000       18 34593084 34593167 84 +      
ENSG00000134769 E023 0.0000000       18 34593318 34593334 17 +      
ENSG00000134769 E024 0.0000000       18 34593335 34593337 3 +      
ENSG00000134769 E025 0.0000000       18 34593338 34593338 1 +      
ENSG00000134769 E026 0.0000000       18 34593339 34593357 19 +      
ENSG00000134769 E027 0.0000000       18 34593358 34593364 7 +      
ENSG00000134769 E028 0.0000000       18 34593365 34593409 45 +      
ENSG00000134769 E029 0.0000000       18 34593410 34593538 129 +      
ENSG00000134769 E030 0.2454580 0.0162537958 7.793301e-01   18 34595786 34595918 133 + 0.111 0.081 -0.508
ENSG00000134769 E031 0.1316618 0.0123366444 7.728590e-01   18 34656241 34656405 165 + 0.000 0.081 11.990
ENSG00000134769 E032 0.2622978 0.3153542896 4.668185e-01   18 34656922 34657019 98 + 0.000 0.149 12.633
ENSG00000134769 E033 0.0000000       18 34662854 34662980 127 +      
ENSG00000134769 E034 3.5678217 0.0047631906 4.391701e-01 0.740261203 18 34679468 34679536 69 + 0.706 0.611 -0.408
ENSG00000134769 E035 3.6463518 0.0051783730 9.035916e-02 0.344998900 18 34679537 34679592 56 + 0.775 0.565 -0.895
ENSG00000134769 E036 0.9013703 0.0148566416 1.296833e-01 0.417905445 18 34683482 34683694 213 + 0.111 0.349 2.077
ENSG00000134769 E037 0.1308632 0.0122424548 7.728984e-01   18 34684174 34684269 96 + 0.000 0.081 11.991
ENSG00000134769 E038 0.1145948 0.0113221388 3.717290e-01   18 34689412 34689570 159 + 0.111 0.000 -13.559
ENSG00000134769 E039 0.0000000       18 34708085 34708173 89 +      
ENSG00000134769 E040 0.0000000       18 34708174 34708226 53 +      
ENSG00000134769 E041 0.0000000       18 34709356 34709373 18 +      
ENSG00000134769 E042 0.0000000       18 34709374 34709503 130 +      
ENSG00000134769 E043 0.0000000       18 34709504 34709517 14 +      
ENSG00000134769 E044 0.0000000       18 34710261 34710283 23 +      
ENSG00000134769 E045 0.0000000       18 34710284 34710293 10 +      
ENSG00000134769 E046 0.0000000       18 34710294 34710296 3 +      
ENSG00000134769 E047 0.0000000       18 34710297 34710297 1 +      
ENSG00000134769 E048 0.0000000       18 34710298 34710317 20 +      
ENSG00000134769 E049 0.0000000       18 34710318 34710426 109 +      
ENSG00000134769 E050 0.0000000       18 34710427 34710445 19 +      
ENSG00000134769 E051 0.0000000       18 34729463 34729546 84 +      
ENSG00000134769 E052 1.6663127 0.0085678232 2.330525e-02 0.158572458 18 34755976 34755976 1 + 0.593 0.260 -1.829
ENSG00000134769 E053 1.7971759 0.0080984961 4.858496e-02 0.243341933 18 34755977 34756043 67 + 0.593 0.307 -1.508
ENSG00000134769 E054 0.1308632 0.0122424548 7.728984e-01   18 34757158 34757288 131 + 0.000 0.081 11.991
ENSG00000134769 E055 0.1315150 0.0122247274 7.730366e-01   18 34763158 34763258 101 + 0.000 0.081 11.991
ENSG00000134769 E056 0.1308632 0.0122424548 7.728984e-01   18 34765782 34765865 84 + 0.000 0.081 11.991
ENSG00000134769 E057 2.1907663 0.0063203913 2.225345e-01 0.546561052 18 34765961 34766041 81 + 0.593 0.422 -0.829
ENSG00000134769 E058 0.0000000       18 34791863 34791991 129 +      
ENSG00000134769 E059 8.3399410 0.0018273995 1.396437e-01 0.432566273 18 34794037 34794250 214 + 1.038 0.902 -0.508
ENSG00000134769 E060 6.3439059 0.0041817852 6.870603e-02 0.297086275 18 34806219 34806304 86 + 0.963 0.773 -0.730
ENSG00000134769 E061 8.1793674 0.0017942975 3.751543e-02 0.210589414 18 34811959 34812113 155 + 1.061 0.867 -0.723
ENSG00000134769 E062 0.9986959 0.0147172646 8.365530e-01 0.945561686 18 34815607 34815908 302 + 0.273 0.307 0.229
ENSG00000134769 E063 6.1344318 0.0306057458 3.851921e-03 0.048386902 18 34815909 34816014 106 + 1.027 0.672 -1.382
ENSG00000134769 E064 0.0000000       18 34817962 34817981 20 +      
ENSG00000134769 E065 0.1316618 0.0123366444 7.728590e-01   18 34817982 34818089 108 + 0.000 0.081 11.990
ENSG00000134769 E066 0.0000000       18 34818090 34818163 74 +      
ENSG00000134769 E067 10.1870978 0.0015358411 1.452648e-03 0.023845172 18 34818164 34818330 167 + 1.185 0.913 -0.993
ENSG00000134769 E068 0.0000000       18 34818381 34818381 1 +      
ENSG00000134769 E069 0.0000000       18 34818382 34818390 9 +      
ENSG00000134769 E070 0.0000000       18 34818391 34818391 1 +      
ENSG00000134769 E071 0.1316618 0.0123366444 7.728590e-01   18 34818392 34818447 56 + 0.000 0.081 11.990
ENSG00000134769 E072 0.1316618 0.0123366444 7.728590e-01   18 34818448 34818472 25 + 0.000 0.081 11.990
ENSG00000134769 E073 0.1316618 0.0123366444 7.728590e-01   18 34818473 34818647 175 + 0.000 0.081 11.990
ENSG00000134769 E074 0.0000000       18 34820597 34820697 101 +      
ENSG00000134769 E075 2.5699803 0.2122622230 3.391926e-01 0.661359460 18 34820791 34820799 9 + 0.625 0.485 -0.646
ENSG00000134769 E076 8.1445356 0.0038230728 1.126961e-02 0.100513824 18 34820800 34820915 116 + 1.083 0.842 -0.897
ENSG00000134769 E077 0.1311489 0.0123966138 7.727745e-01   18 34822362 34822566 205 + 0.000 0.081 11.990
ENSG00000134769 E078 0.1315150 0.0122247274 7.730366e-01   18 34825267 34825275 9 + 0.000 0.081 11.991
ENSG00000134769 E079 6.1775770 0.0083700564 1.489994e-02 0.120027040 18 34827593 34827676 84 + 0.989 0.725 -1.022
ENSG00000134769 E080 2.9102428 0.0053518912 9.354724e-02 0.351678267 18 34829041 34829339 299 + 0.706 0.485 -0.993
ENSG00000134769 E081 0.2453240 0.0164073069 7.803043e-01   18 34829400 34829489 90 + 0.111 0.081 -0.508
ENSG00000134769 E082 0.2628107 0.0162467377 3.915031e-01   18 34838094 34838171 78 + 0.000 0.149 12.900
ENSG00000134769 E083 0.0000000       18 34838745 34838837 93 +      
ENSG00000134769 E084 1.3406205 0.0467720616 4.010863e-01 0.712275965 18 34848296 34848323 28 + 0.440 0.307 -0.771
ENSG00000134769 E085 1.9098581 0.1631175943 1.097328e-01 0.382580365 18 34848324 34848383 60 + 0.624 0.307 -1.645
ENSG00000134769 E086 0.0000000       18 34851786 34851830 45 +      
ENSG00000134769 E087 1.3399656 0.0102717708 3.757050e-01 0.693338363 18 34851831 34851833 3 + 0.440 0.307 -0.771
ENSG00000134769 E088 2.9596008 0.0051368771 6.433218e-01 0.859262377 18 34851834 34851928 95 + 0.624 0.565 -0.267
ENSG00000134769 E089 5.4672358 0.0260143029 9.890465e-01 1.000000000 18 34858285 34858398 114 + 0.796 0.802 0.023
ENSG00000134769 E090 0.2450991 0.0163950298 7.803031e-01   18 34858636 34858706 71 + 0.111 0.081 -0.508
ENSG00000134769 E091 2.6023438 0.0551635026 8.691852e-01 0.958506884 18 34863966 34863969 4 + 0.560 0.540 -0.093
ENSG00000134769 E092 4.3883960 0.0545406920 5.271066e-01 0.797048513 18 34863970 34864062 93 + 0.653 0.758 0.431
ENSG00000134769 E093 0.5263536 0.0349473065 1.025637e-01   18 34866111 34866131 21 + 0.000 0.260 13.751
ENSG00000134769 E094 8.0630099 0.0069973558 1.160382e-01 0.393912629 18 34866132 34868812 2681 + 0.835 1.002 0.630
ENSG00000134769 E095 0.0000000       18 34875237 34875238 2 +      
ENSG00000134769 E096 7.1950040 0.0093344567 9.607298e-02 0.356902051 18 34875239 34875398 160 + 0.775 0.964 0.727
ENSG00000134769 E097 5.2720635 0.0027812969 3.026775e-01 0.629738674 18 34877719 34877808 90 + 0.706 0.829 0.492
ENSG00000134769 E098 8.0005025 0.0022022878 2.859866e-01 0.613508642 18 34879551 34879719 169 + 1.002 0.902 -0.374
ENSG00000134769 E099 2.2612495 0.0355131308 5.268104e-01 0.796829461 18 34882069 34882088 20 + 0.440 0.540 0.493
ENSG00000134769 E100 5.6192869 0.0419236037 7.161082e-01 0.894899273 18 34882089 34882201 113 + 0.775 0.829 0.212
ENSG00000134769 E101 3.6727777 0.0057946267 1.354137e-01 0.426506379 18 34884728 34884776 49 + 0.523 0.725 0.885
ENSG00000134769 E102 83.5874026 0.0001948844 6.484199e-02 0.287376287 18 34887766 34890299 2534 + 1.878 1.936 0.195
ENSG00000134769 E103 79.6705251 0.0004632340 3.940052e-05 0.001364394 18 34890300 34891844 1545 + 1.807 1.940 0.448

Help

Please Click HERE to learn more details about the results from DEXseq.