ENSG00000136144

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258646 ENSG00000136144 No_inf pgwt_inf RCBTB1 protein_coding protein_coding 10.47759 11.61594 8.821878 1.263162 1.720657 -0.3965555 1.9893742 3.1491418 1.6036555 0.9532026 1.6036555 -0.9692001 0.16554167 0.257900 0.166300 -0.091600 0.7299391 0.0043286 FALSE TRUE
ENST00000378302 ENSG00000136144 No_inf pgwt_inf RCBTB1 protein_coding protein_coding 10.47759 11.61594 8.821878 1.263162 1.720657 -0.3965555 3.6413474 1.8610847 4.5833838 1.1464926 1.1781994 1.2956825 0.42404167 0.186275 0.621500 0.435225 0.9607349 0.0043286 FALSE TRUE
ENST00000490058 ENSG00000136144 No_inf pgwt_inf RCBTB1 protein_coding protein_coding_CDS_not_defined 10.47759 11.61594 8.821878 1.263162 1.720657 -0.3965555 0.4726478 1.4179433 0.0000000 1.4179433 0.0000000 -7.1577949 0.03083333 0.092500 0.000000 -0.092500 0.9928472 0.0043286   FALSE
MSTRG.7828.1 ENSG00000136144 No_inf pgwt_inf RCBTB1 protein_coding   10.47759 11.61594 8.821878 1.263162 1.720657 -0.3965555 1.0215806 0.9965385 0.1790153 0.9965385 0.1790153 -2.4128272 0.10425000 0.091375 0.013400 -0.077975 1.0000000 0.0043286 FALSE TRUE
MSTRG.7828.4 ENSG00000136144 No_inf pgwt_inf RCBTB1 protein_coding   10.47759 11.61594 8.821878 1.263162 1.720657 -0.3965555 1.7587167 3.7650684 0.0000000 0.9071507 0.0000000 -8.5603590 0.16206667 0.344150 0.000000 -0.344150 0.0043286 0.0043286 TRUE TRUE
MSTRG.7828.6 ENSG00000136144 No_inf pgwt_inf RCBTB1 protein_coding   10.47759 11.61594 8.821878 1.263162 1.720657 -0.3965555 1.2798767 0.0000000 1.9398427 0.0000000 1.9398427 7.6072140 0.08615833 0.000000 0.145275 0.145275 0.9928472 0.0043286   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000136144 E001 0.1141751 0.0112151277 0.419300074   13 49531946 49531955 10 - 0.106 0.000 -9.843
ENSG00000136144 E002 65.3320722 0.0007409175 0.002282283 0.03344114 13 49531956 49533265 1310 - 1.753 1.851 0.333
ENSG00000136144 E003 16.8838373 0.0009770828 0.494484890 0.77675227 13 49533266 49533485 220 - 1.272 1.226 -0.162
ENSG00000136144 E004 26.4673906 0.0008549088 0.878409821 0.96134036 13 49533486 49533917 432 - 1.436 1.428 -0.026
ENSG00000136144 E005 19.4984157 0.0007535381 0.509041644 0.78600886 13 49533918 49534262 345 - 1.278 1.321 0.150
ENSG00000136144 E006 0.0000000       13 49537870 49538070 201 -      
ENSG00000136144 E007 0.0000000       13 49538071 49538083 13 -      
ENSG00000136144 E008 0.0000000       13 49539375 49539503 129 -      
ENSG00000136144 E009 6.6788508 0.0021490627 0.933626416 0.98157154 13 49540876 49541006 131 - 0.883 0.875 -0.029
ENSG00000136144 E010 5.0569027 0.0032367176 0.750757199 0.91064888 13 49541676 49541827 152 - 0.796 0.761 -0.140
ENSG00000136144 E011 5.2718458 0.0034233074 0.162470322 0.46648816 13 49544737 49544863 127 - 0.688 0.849 0.649
ENSG00000136144 E012 1.6744309 0.1588976961 0.083941386 0.33135450 13 49544864 49544993 130 - 0.191 0.530 2.109
ENSG00000136144 E013 6.2155718 0.0024277518 0.113986071 0.39036639 13 49549458 49549648 191 - 0.942 0.777 -0.635
ENSG00000136144 E014 0.3945449 0.6360812578 0.416906554   13 49551171 49551325 155 - 0.000 0.218 11.306
ENSG00000136144 E015 5.2562202 0.0026933750 0.279996053 0.60812824 13 49551326 49551468 143 - 0.712 0.836 0.497
ENSG00000136144 E016 4.0029596 0.0056290004 0.120241074 0.40120161 13 49552178 49552285 108 - 0.796 0.606 -0.792
ENSG00000136144 E017 5.0390377 0.0059578303 0.538713858 0.80418391 13 49555515 49555673 159 - 0.815 0.744 -0.281
ENSG00000136144 E018 2.8167357 0.0942195612 0.524062573 0.79509533 13 49559918 49559967 50 - 0.635 0.530 -0.477
ENSG00000136144 E019 4.3676319 0.0094957627 0.092163948 0.34863904 13 49559968 49560084 117 - 0.833 0.629 -0.837
ENSG00000136144 E020 4.5650315 0.0032464829 0.801916108 0.93214513 13 49566618 49566768 151 - 0.756 0.727 -0.117
ENSG00000136144 E021 6.3473797 0.0022587569 0.148698701 0.44575184 13 49567154 49567320 167 - 0.942 0.793 -0.574
ENSG00000136144 E022 0.3589051 0.0164724538 0.442555751   13 49567321 49567323 3 - 0.191 0.085 -1.351
ENSG00000136144 E023 2.8419232 0.0066530842 0.002208779 0.03268894 13 49580505 49580580 76 - 0.777 0.362 -1.936
ENSG00000136144 E024 0.7014837 0.0586353723 0.055810076 0.26398034 13 49580581 49580584 4 - 0.377 0.085 -2.673
ENSG00000136144 E025 1.7974518 0.0098201899 0.079406642 0.32173569 13 49585444 49585580 137 - 0.576 0.319 -1.351

Help

Please Click HERE to learn more details about the results from DEXseq.