ENSG00000136169

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000611815 ENSG00000136169 No_inf pgwt_inf SETDB2 protein_coding protein_coding 73.17001 129.9501 73.60679 36.92297 35.61225 -0.8199615 3.2936755 5.070443 1.257359 2.0856981 0.8371402 -2.0031291 0.121175 0.047600 0.073050 0.025450 0.993236612 0.002293681 FALSE TRUE
MSTRG.7831.2 ENSG00000136169 No_inf pgwt_inf SETDB2 protein_coding   73.17001 129.9501 73.60679 36.92297 35.61225 -0.8199615 0.8173285 0.000000 2.182344 0.0000000 0.2626451 7.7763301 0.024450 0.000000 0.061775 0.061775 0.002293681 0.002293681   FALSE
MSTRG.7831.8 ENSG00000136169 No_inf pgwt_inf SETDB2 protein_coding   73.17001 129.9501 73.60679 36.92297 35.61225 -0.8199615 51.9623128 99.836628 56.050310 37.3016648 35.8061865 -0.8327340 0.374325 0.694475 0.428500 -0.265975 0.992847247 0.002293681   FALSE
MSTRG.7831.9 ENSG00000136169 No_inf pgwt_inf SETDB2 protein_coding   73.17001 129.9501 73.60679 36.92297 35.61225 -0.8199615 13.1163991 18.658227 10.716077 0.4779854 1.2996552 -0.7994624 0.385825 0.187050 0.368250 0.181200 0.992847247 0.002293681   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000136169 E001 0.3592640 0.0165768479 2.000741e-01   13 49444274 49444312 39 + 0.240 0.065 -2.186
ENSG00000136169 E002 1.4540470 0.0097620889 4.894233e-02 2.443250e-01 13 49444313 49444372 60 + 0.555 0.258 -1.672
ENSG00000136169 E003 1.0947831 0.0116834158 1.237019e-01 4.074731e-01 13 49444373 49444373 1 + 0.454 0.217 -1.508
ENSG00000136169 E004 10.1134913 0.0065003202 3.821147e-03 4.817132e-02 13 49444374 49444683 310 + 1.177 0.911 -0.975
ENSG00000136169 E005 8.1775877 0.0159456730 7.772151e-01 9.226825e-01 13 49444684 49444857 174 + 0.942 0.911 -0.119
ENSG00000136169 E006 0.2623781 0.0160230081 6.988849e-01   13 49445553 49445952 400 + 0.001 0.122 7.944
ENSG00000136169 E007 0.0000000       13 49451552 49451552 1 +      
ENSG00000136169 E008 2.9171014 0.0058439053 6.450584e-01 8.597216e-01 13 49451553 49451583 31 + 0.507 0.575 0.316
ENSG00000136169 E009 14.4334676 0.0009602122 3.305066e-04 7.621752e-03 13 49451584 49451909 326 + 1.321 1.050 -0.964
ENSG00000136169 E010 9.9749172 0.0152600764 8.126324e-01 9.362412e-01 13 49460107 49460232 126 + 0.977 1.004 0.097
ENSG00000136169 E011 6.5846902 0.0034413329 5.776825e-01 8.255516e-01 13 49461097 49461162 66 + 0.790 0.855 0.254
ENSG00000136169 E012 1.2607935 0.1009261362 9.446135e-01 9.861148e-01 13 49463051 49463097 47 + 0.324 0.330 0.037
ENSG00000136169 E013 1.2610723 0.0108194051 9.739900e-01 9.954881e-01 13 49464021 49464030 10 + 0.324 0.330 0.036
ENSG00000136169 E014 1.7351813 0.0851228932 3.797419e-01 6.963619e-01 13 49464031 49464056 26 + 0.507 0.361 -0.771
ENSG00000136169 E015 3.9462451 0.1301515503 4.363683e-01 7.381870e-01 13 49464921 49465035 115 + 0.554 0.690 0.591
ENSG00000136169 E016 8.9558547 0.0016601380 7.805292e-02 3.187573e-01 13 49467864 49467960 97 + 1.069 0.902 -0.618
ENSG00000136169 E017 18.6045762 0.0028295044 6.943210e-02 2.987419e-01 13 49476476 49476698 223 + 1.336 1.207 -0.454
ENSG00000136169 E018 6.2889525 0.0214791914 8.335964e-01 9.441900e-01 13 49476699 49476774 76 + 0.839 0.814 -0.099
ENSG00000136169 E019 3.0135165 0.0047431200 7.657336e-01 9.170216e-01 13 49476775 49476792 18 + 0.597 0.556 -0.186
ENSG00000136169 E020 18.2737722 0.0008585797 1.789019e-01 4.911659e-01 13 49476793 49477039 247 + 1.305 1.211 -0.332
ENSG00000136169 E021 15.3503078 0.0008998764 2.323272e-01 5.579426e-01 13 49480219 49480335 117 + 1.095 1.193 0.351
ENSG00000136169 E022 17.8116253 0.0009106602 2.538921e-02 1.673053e-01 13 49480947 49481116 170 + 1.336 1.180 -0.551
ENSG00000136169 E023 27.0634120 0.0009301053 7.142526e-01 8.939937e-01 13 49482737 49482962 226 + 1.417 1.395 -0.074
ENSG00000136169 E024 11.4568418 0.0318731192 2.004974e-01 5.189693e-01 13 49483464 49483563 100 + 0.942 1.086 0.530
ENSG00000136169 E025 4.7030422 0.0295904465 4.454080e-01 7.442903e-01 13 49485630 49485644 15 + 0.636 0.744 0.451
ENSG00000136169 E026 10.2395825 0.0015364697 6.788727e-01 8.763407e-01 13 49485645 49485723 79 + 0.977 1.018 0.148
ENSG00000136169 E027 6.6202431 0.0022374499 2.346359e-01 5.598043e-01 13 49488290 49488291 2 + 0.735 0.875 0.551
ENSG00000136169 E028 42.5927509 0.0003568646 9.055273e-01 9.722385e-01 13 49488292 49488630 339 + 1.596 1.591 -0.016
ENSG00000136169 E029 12.8711237 0.0011761470 8.129301e-01 9.363732e-01 13 49490822 49490910 89 + 1.082 1.103 0.077
ENSG00000136169 E030 86.8946393 0.0003071335 1.366458e-07 9.276188e-06 13 49491732 49495003 3272 + 1.760 1.939 0.604

Help

Please Click HERE to learn more details about the results from DEXseq.