ENSG00000136231

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000258729 ENSG00000136231 No_inf pgwt_inf IGF2BP3 protein_coding protein_coding 13.55726 32.33623 2.710351 19.44568 0.5607064 -3.571733 0.9165358 0.10281688 1.3521652 0.10281688 0.2763122 3.593847 0.31651667 0.001250 0.598350 0.597100 0.02188994 0.02188994 FALSE TRUE
ENST00000421467 ENSG00000136231 No_inf pgwt_inf IGF2BP3 protein_coding nonsense_mediated_decay 13.55726 32.33623 2.710351 19.44568 0.5607064 -3.571733 0.3213553 0.26051160 0.0000000 0.18323281 0.0000000 -4.757619 0.11005000 0.228450 0.000000 -0.228450 1.00000000 0.02188994 FALSE TRUE
ENST00000480547 ENSG00000136231 No_inf pgwt_inf IGF2BP3 protein_coding retained_intron 13.55726 32.33623 2.710351 19.44568 0.5607064 -3.571733 0.3576386 0.00000000 0.3439528 0.00000000 0.3439528 5.145485 0.07611667 0.000000 0.099100 0.099100 0.99284725 0.02188994 FALSE FALSE
ENST00000497563 ENSG00000136231 No_inf pgwt_inf IGF2BP3 protein_coding protein_coding_CDS_not_defined 13.55726 32.33623 2.710351 19.44568 0.5607064 -3.571733 0.4294748 0.15764761 0.0000000 0.15764761 0.0000000 -4.067360 0.05162500 0.003700 0.000000 -0.003700 1.00000000 0.02188994   FALSE
ENST00000498363 ENSG00000136231 No_inf pgwt_inf IGF2BP3 protein_coding retained_intron 13.55726 32.33623 2.710351 19.44568 0.5607064 -3.571733 0.4180823 0.93250458 0.3217423 0.54782002 0.3217423 -1.506437 0.09827500 0.205950 0.088875 -0.117075 1.00000000 0.02188994 FALSE FALSE
ENST00000619562 ENSG00000136231 No_inf pgwt_inf IGF2BP3 protein_coding protein_coding 13.55726 32.33623 2.710351 19.44568 0.5607064 -3.571733 0.3832162 0.06245465 0.5644339 0.06245465 0.3586271 2.986991 0.08910000 0.001450 0.177350 0.175900 0.82159308 0.02188994 FALSE TRUE
MSTRG.25922.9 ENSG00000136231 No_inf pgwt_inf IGF2BP3 protein_coding   13.55726 32.33623 2.710351 19.44568 0.5607064 -3.571733 10.1541707 30.46251217 0.0000000 19.66133965 0.0000000 -11.573293 0.15965833 0.478975 0.000000 -0.478975 0.97861188 0.02188994   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000136231 E001 0.0000000       7 23310209 23311126 918 -      
ENSG00000136231 E002 0.0000000       7 23311127 23311240 114 -      
ENSG00000136231 E003 5.5391007 0.216866682 0.673630949 0.87378700 7 23311241 23312372 1132 - 0.815 0.700 -0.464
ENSG00000136231 E004 2.1207748 0.007901563 0.880307755 0.96210650 7 23312373 23312460 88 - 0.490 0.416 -0.383
ENSG00000136231 E005 1.9271724 0.048577180 0.238322696 0.56401525 7 23312735 23312848 114 - 0.397 0.532 0.688
ENSG00000136231 E006 1.7352612 0.009906119 0.006699468 0.07112139 7 23313522 23313653 132 - 0.278 0.624 1.840
ENSG00000136231 E007 0.9640868 0.062769253 0.410513234 0.71917117 7 23317639 23317692 54 - 0.242 0.343 0.688
ENSG00000136231 E008 0.8325718 0.181759030 0.821116452 0.93906007 7 23317693 23317713 21 - 0.242 0.256 0.102
ENSG00000136231 E009 0.6050911 0.517031758 0.616141328   7 23317714 23317833 120 - 0.161 0.256 0.838
ENSG00000136231 E010 0.7978633 0.013992817 0.129644813 0.41790544 7 23319138 23319254 117 - 0.311 0.000 -13.908
ENSG00000136231 E011 0.4555123 0.016674659 0.401212493   7 23342064 23342065 2 - 0.203 0.000 -13.101
ENSG00000136231 E012 0.5694625 0.017397533 0.270976399   7 23342066 23342095 30 - 0.242 0.000 -13.422
ENSG00000136231 E013 0.9292340 0.014019628 0.443719186 0.74341277 7 23342096 23342189 94 - 0.311 0.146 -1.383
ENSG00000136231 E014 1.2887229 0.013038649 0.657555637 0.86632395 7 23343718 23343852 135 - 0.370 0.256 -0.745
ENSG00000136231 E015 0.7194806 0.017801152 0.589606975 0.83223608 7 23343853 23343853 1 - 0.203 0.256 0.425
ENSG00000136231 E016 1.9294718 0.041592487 0.224264818 0.54845543 7 23345940 23346062 123 - 0.397 0.532 0.688
ENSG00000136231 E017 0.0000000       7 23346063 23346158 96 -      
ENSG00000136231 E018 0.1316618 0.013197245 0.138434145   7 23346159 23346205 47 - 0.000 0.146 13.746
ENSG00000136231 E019 1.0430556 0.012917277 0.349382488 0.67000817 7 23347600 23347630 31 - 0.342 0.146 -1.575
ENSG00000136231 E020 0.4557372 0.016128834 0.397719705   7 23347631 23347648 18 - 0.203 0.000 -13.101
ENSG00000136231 E021 0.5695432 0.016625811 0.268223349   7 23347649 23347662 14 - 0.242 0.000 -13.422
ENSG00000136231 E022 0.6834934 0.014497644 0.184625845 0.49807972 7 23347663 23347698 36 - 0.278 0.000 -13.685
ENSG00000136231 E023 0.5695432 0.016625811 0.268223349   7 23347699 23347723 25 - 0.242 0.000 -13.422
ENSG00000136231 E024 0.3415621 0.017177156 0.623384387   7 23347724 23347734 11 - 0.161 0.000 -12.686
ENSG00000136231 E025 0.0000000       7 23347735 23347812 78 -      
ENSG00000136231 E026 0.9289616 0.013202933 0.439357518 0.74036546 7 23351305 23351386 82 - 0.311 0.146 -1.383
ENSG00000136231 E027 0.7010612 0.015733394 0.709538045 0.89204350 7 23351387 23351443 57 - 0.242 0.146 -0.897
ENSG00000136231 E028 0.5866612 0.015861320 0.953324836   7 23351444 23351479 36 - 0.203 0.146 -0.575
ENSG00000136231 E029 0.5874501 0.015824992 0.942719600   7 23351480 23351505 26 - 0.203 0.146 -0.575
ENSG00000136231 E030 0.8158003 0.014336593 0.554229342 0.81334160 7 23351506 23351586 81 - 0.278 0.146 -1.160
ENSG00000136231 E031 0.0000000       7 23361341 23361533 193 -      
ENSG00000136231 E032 0.6057501 0.018872882 0.420568752   7 23361534 23361597 64 - 0.161 0.256 0.840
ENSG00000136231 E033 0.8349397 0.343504332 0.906507238 0.97241288 7 23361690 23361741 52 - 0.242 0.256 0.102
ENSG00000136231 E034 0.0000000       7 23362527 23362675 149 -      
ENSG00000136231 E035 0.0000000       7 23394584 23394677 94 -      
ENSG00000136231 E036 0.0000000       7 23402245 23402570 326 -      
ENSG00000136231 E037 0.0000000       7 23402571 23402585 15 -      
ENSG00000136231 E038 0.0000000       7 23402586 23402710 125 -      
ENSG00000136231 E039 0.0000000       7 23405019 23405110 92 -      
ENSG00000136231 E040 0.4896240 0.019784680 0.247808444   7 23413244 23415565 2322 - 0.114 0.256 1.425
ENSG00000136231 E041 0.1138060 0.011415018 1.000000000   7 23416129 23416219 91 - 0.060 0.000 -11.101
ENSG00000136231 E042 0.4914307 0.076966099 0.268167573   7 23418776 23418824 49 - 0.114 0.256 1.425
ENSG00000136231 E043 0.0000000       7 23431169 23431303 135 -      
ENSG00000136231 E044 0.0000000       7 23467772 23467926 155 -      
ENSG00000136231 E045 0.7016221 0.014578162 0.713897023 0.89390192 7 23468482 23468515 34 - 0.242 0.146 -0.897
ENSG00000136231 E046 0.7186891 0.015211872 0.586047452 0.83020001 7 23468516 23468542 27 - 0.203 0.256 0.425
ENSG00000136231 E047 0.0000000       7 23469236 23469502 267 -      
ENSG00000136231 E048 1.0606204 0.012306032 0.921824166 0.97783910 7 23469936 23470008 73 - 0.311 0.256 -0.383
ENSG00000136231 E049 1.0594557 0.012282001 0.921773457 0.97783910 7 23470009 23470491 483 - 0.311 0.256 -0.383

Help

Please Click HERE to learn more details about the results from DEXseq.