ENSG00000136536

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000259050 ENSG00000136536 No_inf pgwt_inf MARCHF7 protein_coding protein_coding 53.04904 40.00738 52.67382 5.447317 7.849418 0.3967332 5.521397 3.729866 7.214706 2.1626382 3.1971510 0.94995207 0.09232500 0.077950 0.127225 0.049275 0.9928472467 0.0004085314 FALSE TRUE
ENST00000461582 ENSG00000136536 No_inf pgwt_inf MARCHF7 protein_coding protein_coding_CDS_not_defined 53.04904 40.00738 52.67382 5.447317 7.849418 0.3967332 20.175217 9.039476 20.896056 5.8664209 7.9338896 1.20801480 0.30844167 0.181450 0.346975 0.165525 0.9928472467 0.0004085314   FALSE
ENST00000473749 ENSG00000136536 No_inf pgwt_inf MARCHF7 protein_coding protein_coding_CDS_not_defined 53.04904 40.00738 52.67382 5.447317 7.849418 0.3967332 2.946718 0.000000 5.205580 0.0000000 1.3124650 9.02668398 0.05365833 0.000000 0.101150 0.101150 0.0004085314 0.0004085314 FALSE TRUE
MSTRG.17176.2 ENSG00000136536 No_inf pgwt_inf MARCHF7 protein_coding   53.04904 40.00738 52.67382 5.447317 7.849418 0.3967332 14.118613 14.100314 10.290562 2.8566250 3.9934650 -0.45402697 0.32095000 0.397375 0.242725 -0.154650 0.9928472467 0.0004085314 FALSE TRUE
MSTRG.17176.4 ENSG00000136536 No_inf pgwt_inf MARCHF7 protein_coding   53.04904 40.00738 52.67382 5.447317 7.849418 0.3967332 3.531994 3.619531 3.536447 0.3830228 0.4595770 -0.03340875 0.07663333 0.094475 0.076250 -0.018225 0.9928472467 0.0004085314 TRUE TRUE
MSTRG.17176.7 ENSG00000136536 No_inf pgwt_inf MARCHF7 protein_coding   53.04904 40.00738 52.67382 5.447317 7.849418 0.3967332 4.044142 6.339929 3.140528 0.1107749 0.1784323 -1.01114677 0.09116667 0.166425 0.063375 -0.103050 0.7094767678 0.0004085314 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000136536 E001 0.0000000       2 159712457 159712481 25 +      
ENSG00000136536 E002 0.1141751 1.119590e-02 4.634304e-01   2 159712482 159712498 17 + 0.102 0.000 -10.202
ENSG00000136536 E003 0.1141751 1.119590e-02 4.634304e-01   2 159712499 159712502 4 + 0.102 0.000 -12.292
ENSG00000136536 E004 0.6212255 1.609954e-01 7.983329e-01   2 159712503 159712505 3 + 0.184 0.225 0.365
ENSG00000136536 E005 0.6212255 1.609954e-01 7.983329e-01   2 159712506 159712506 1 + 0.184 0.225 0.365
ENSG00000136536 E006 0.9806337 4.261148e-02 8.322328e-01 9.436758e-01 2 159712507 159712513 7 + 0.313 0.280 -0.219
ENSG00000136536 E007 3.1887353 5.075280e-03 7.074413e-01 8.909678e-01 2 159712514 159712522 9 + 0.647 0.597 -0.219
ENSG00000136536 E008 14.1398721 1.348082e-02 1.417245e-01 4.353472e-01 2 159712523 159712606 84 + 1.246 1.115 -0.468
ENSG00000136536 E009 10.0395618 1.253934e-02 4.166922e-01 7.236733e-01 2 159712607 159712661 55 + 1.083 1.003 -0.290
ENSG00000136536 E010 0.3759015 1.640164e-01 7.158992e-01   2 159714499 159714556 58 + 0.102 0.162 0.781
ENSG00000136536 E011 1.7168072 7.968177e-03 7.833480e-01 9.248906e-01 2 159714557 159714598 42 + 0.455 0.413 -0.219
ENSG00000136536 E012 0.1311489 1.221771e-02 6.232032e-01   2 159715580 159715631 52 + 0.000 0.089 11.093
ENSG00000136536 E013 1.4892502 9.493325e-02 7.803586e-01 9.239888e-01 2 159715681 159715766 86 + 0.366 0.413 0.267
ENSG00000136536 E014 35.9719958 3.828438e-04 4.777461e-02 2.410572e-01 2 159729009 159729175 167 + 1.617 1.518 -0.337
ENSG00000136536 E015 0.8845460 1.312407e-02 3.425966e-01 6.641500e-01 2 159733965 159734082 118 + 0.184 0.329 1.103
ENSG00000136536 E016 46.4435088 5.855287e-03 3.560757e-01 6.760841e-01 2 159743061 159743253 193 + 1.700 1.649 -0.173
ENSG00000136536 E017 38.6176526 3.643669e-04 4.507238e-01 7.482901e-01 2 159745770 159745937 168 + 1.614 1.577 -0.127
ENSG00000136536 E018 58.2475449 3.467858e-04 1.062295e-02 9.651377e-02 2 159747805 159748113 309 + 1.823 1.722 -0.340
ENSG00000136536 E019 74.7841846 2.329281e-04 6.784231e-06 3.013788e-04 2 159748114 159748489 376 + 1.957 1.802 -0.521
ENSG00000136536 E020 101.3865299 1.612844e-04 3.146106e-04 7.354213e-03 2 159748490 159748903 414 + 2.063 1.957 -0.355
ENSG00000136536 E021 38.0908908 2.904033e-03 9.285802e-02 3.500789e-01 2 159752402 159752489 88 + 1.636 1.547 -0.303
ENSG00000136536 E022 38.3356096 3.671966e-04 6.733576e-02 2.939334e-01 2 159752490 159752571 82 + 1.639 1.550 -0.302
ENSG00000136536 E023 33.6256625 4.430233e-04 2.183848e-01 5.414454e-01 2 159759226 159759291 66 + 1.570 1.506 -0.219
ENSG00000136536 E024 26.6398132 5.251442e-04 3.054044e-01 6.324566e-01 2 159759292 159759335 44 + 1.470 1.411 -0.206
ENSG00000136536 E025 0.7548834 3.814067e-01 6.355532e-01 8.548438e-01 2 159759336 159759358 23 + 0.184 0.281 0.780
ENSG00000136536 E026 50.4215765 1.651135e-03 4.400685e-01 7.408111e-01 2 159762880 159762993 114 + 1.727 1.691 -0.121
ENSG00000136536 E027 50.6732515 2.885428e-04 2.673962e-05 9.809948e-04 2 159762994 159764625 1632 + 1.597 1.777 0.608
ENSG00000136536 E028 34.6515566 5.818340e-03 1.523600e-01 4.517528e-01 2 159764626 159764674 49 + 1.594 1.509 -0.290
ENSG00000136536 E029 119.5451880 1.359755e-04 1.401366e-10 1.613729e-08 2 159764675 159767283 2609 + 1.968 2.143 0.586
ENSG00000136536 E030 408.2789780 6.000584e-05 9.204339e-07 5.282395e-05 2 159767284 159771027 3744 + 2.572 2.632 0.201

Help

Please Click HERE to learn more details about the results from DEXseq.