ENSG00000137713

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000311129 ENSG00000137713 No_inf pgwt_inf PPP2R1B protein_coding protein_coding 14.08618 8.311462 20.45198 0.4453822 8.197136 1.298037 0.9447912 0.5712008 0.5263352 0.4508707 0.3620128 -0.11590180 0.07809167 0.069950 0.031350 -0.038600 0.99284725 0.01360256 FALSE TRUE
ENST00000341980 ENSG00000137713 No_inf pgwt_inf PPP2R1B protein_coding protein_coding 14.08618 8.311462 20.45198 0.4453822 8.197136 1.298037 1.4661570 0.0000000 3.3040083 0.0000000 0.3579805 8.37243341 0.09577500 0.000000 0.210575 0.210575 0.01360256 0.01360256 FALSE TRUE
ENST00000527614 ENSG00000137713 No_inf pgwt_inf PPP2R1B protein_coding protein_coding 14.08618 8.311462 20.45198 0.4453822 8.197136 1.298037 7.3693865 6.7170142 6.3576563 0.3330984 0.2007117 -0.07920383 0.64070833 0.818025 0.433800 -0.384225 0.74506013 0.01360256 FALSE TRUE
ENST00000530787 ENSG00000137713 No_inf pgwt_inf PPP2R1B protein_coding protein_coding_CDS_not_defined 14.08618 8.311462 20.45198 0.4453822 8.197136 1.298037 2.7678818 0.0000000 8.3036454 0.0000000 8.3036454 9.69933741 0.06150833 0.000000 0.184525 0.184525 0.99988926 0.01360256   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000137713 E001 0.0000000       11 111726908 111726913 6 -      
ENSG00000137713 E002 0.0000000       11 111726914 111726969 56 -      
ENSG00000137713 E003 0.0000000       11 111726970 111727057 88 -      
ENSG00000137713 E004 0.2285450 0.0154928372 3.073685e-01   11 111735281 111735325 45 - 0.161 0.000 -9.659
ENSG00000137713 E005 0.7695504 0.8297640879 5.346378e-01 8.013830e-01 11 111737448 111737569 122 - 0.088 0.368 2.566
ENSG00000137713 E006 101.9869469 0.0002074905 2.995899e-11 3.888515e-09 11 111737877 111741054 3178 - 1.924 2.088 0.550
ENSG00000137713 E007 20.4170233 0.0120356343 7.461475e-01 9.090169e-01 11 111741055 111741320 266 - 1.318 1.343 0.089
ENSG00000137713 E008 18.9118052 0.0007644843 9.790934e-01 9.973230e-01 11 111741321 111741516 196 - 1.299 1.299 0.002
ENSG00000137713 E009 7.6878667 0.0019648387 9.603874e-01 9.904637e-01 11 111741517 111741547 31 - 0.937 0.941 0.015
ENSG00000137713 E010 9.6120552 0.0018939603 5.231372e-02 2.546654e-01 11 111741548 111741612 65 - 1.104 0.927 -0.649
ENSG00000137713 E011 5.0520315 0.0028073440 1.922357e-01 5.075161e-01 11 111742053 111742056 4 - 0.850 0.699 -0.604
ENSG00000137713 E012 9.1706020 0.0014612339 1.830024e-01 4.958419e-01 11 111742057 111742144 88 - 1.063 0.941 -0.452
ENSG00000137713 E013 1.2266033 0.0114863483 7.900248e-01 9.273873e-01 11 111742145 111742522 378 - 0.327 0.368 0.244
ENSG00000137713 E014 12.5441742 0.0035502230 8.379582e-01 9.460665e-01 11 111742523 111742665 143 - 1.141 1.122 -0.065
ENSG00000137713 E015 13.0855087 0.0427751037 7.368914e-01 9.044327e-01 11 111743376 111743530 155 - 1.133 1.164 0.110
ENSG00000137713 E016 6.1006451 0.0022605610 9.666297e-01 9.926832e-01 11 111747954 111748014 61 - 0.850 0.853 0.013
ENSG00000137713 E017 11.5664429 0.0012245820 7.699968e-01 9.193273e-01 11 111752159 111752332 174 - 1.111 1.086 -0.091
ENSG00000137713 E018 10.5987123 0.0126031587 8.730408e-01 9.601520e-01 11 111753443 111753577 135 - 1.072 1.057 -0.055
ENSG00000137713 E019 7.4205855 0.0032866807 3.293570e-02 1.945720e-01 11 111754499 111754569 71 - 1.019 0.801 -0.826
ENSG00000137713 E020 9.5240495 0.0016044146 1.872439e-03 2.887864e-02 11 111754980 111755094 115 - 1.141 0.853 -1.065
ENSG00000137713 E021 7.8775521 0.0022105639 1.087822e-02 9.806633e-02 11 111755295 111755450 156 - 1.055 0.801 -0.957
ENSG00000137713 E022 3.6127139 0.0212973993 3.514190e-01 6.716626e-01 11 111759804 111759813 10 - 0.722 0.595 -0.544
ENSG00000137713 E023 7.6211242 0.0025466575 3.389501e-01 6.612819e-01 11 111759814 111759951 138 - 0.980 0.884 -0.360
ENSG00000137713 E024 9.1051130 0.0015926395 2.293906e-02 1.572295e-01 11 111760819 111760955 137 - 1.096 0.884 -0.784
ENSG00000137713 E025 8.4749273 0.0656827272 5.007039e-02 2.480206e-01 11 111760956 111761051 96 - 1.080 0.836 -0.911
ENSG00000137713 E026 0.2626639 0.0162178471 1.886131e-01   11 111761119 111761291 173 - 0.000 0.186 11.276
ENSG00000137713 E027 9.2674850 0.0277261392 9.836416e-01 9.987491e-01 11 111764805 111764905 101 - 1.009 1.014 0.016
ENSG00000137713 E028 6.4938253 0.0022544885 6.259367e-01 8.502374e-01 11 111765294 111765384 91 - 0.850 0.899 0.190
ENSG00000137713 E029 0.0000000       11 111765798 111766247 450 -      
ENSG00000137713 E030 6.4384846 0.0021495760 1.601130e-02 1.256601e-01 11 111766248 111766389 142 - 0.980 0.721 -1.003

Help

Please Click HERE to learn more details about the results from DEXseq.