ENSG00000137822

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000260383 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding protein_coding 7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 0.7214814 0.0000000 1.4143547 0.0000000 0.5939570 7.1541646 0.10130833 0.000000 0.176650 0.176650 0.396662257 0.002421956 FALSE TRUE
ENST00000561691 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding nonsense_mediated_decay 7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 0.5928691 0.8866461 0.1081854 0.5491385 0.1081854 -2.9234866 0.07819167 0.100925 0.013850 -0.087075 0.992847247 0.002421956 TRUE TRUE
ENST00000564079 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding protein_coding 7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 2.7456238 1.1861227 2.9645906 0.4148205 0.8281996 1.3143257 0.42201667 0.206700 0.369825 0.163125 0.992847247 0.002421956 FALSE TRUE
ENST00000565548 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding protein_coding 7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 0.6007913 1.8023739 0.0000000 0.5058785 0.0000000 -7.5017368 0.08182500 0.245475 0.000000 -0.245475 0.002421956 0.002421956 FALSE FALSE
ENST00000566251 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding nonsense_mediated_decay 7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 0.3233616 0.0000000 0.9700848 0.0000000 0.7463117 6.6148347 0.03595833 0.000000 0.107875 0.107875 0.984358777 0.002421956   FALSE
ENST00000570081 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding protein_coding_CDS_not_defined 7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 0.4934861 1.1023533 0.2102188 0.6929293 0.2102188 -2.3366053 0.05957500 0.124650 0.028625 -0.096025 0.992847247 0.002421956   FALSE
MSTRG.9408.2 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding   7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 0.2043302 0.4060124 0.2069781 0.2754420 0.2069781 -0.9390772 0.03498333 0.080600 0.024350 -0.056250 0.992847247 0.002421956 TRUE TRUE
MSTRG.9408.4 ENSG00000137822 No_inf pgwt_inf TUBGCP4 protein_coding   7.06146 6.968676 8.190748 1.243395 0.389468 0.2328022 0.4043506 0.1573565 1.0556953 0.1573565 0.6124277 2.6707987 0.05119167 0.027375 0.126200 0.098825 0.992847247 0.002421956 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000137822 E001 0.7529476 0.0624931772 1.667829e-01 0.4728774964 15 43369221 43369411 191 + 0.139 0.356 1.748
ENSG00000137822 E002 0.0000000       15 43369601 43369702 102 +      
ENSG00000137822 E003 0.0000000       15 43371073 43371087 15 +      
ENSG00000137822 E004 0.3596331 0.0167471461 1.000000e+00   15 43371088 43371100 13 + 0.139 0.120 -0.252
ENSG00000137822 E005 4.3780651 0.0039485955 8.775268e-02 0.3399575714 15 43371101 43371432 332 + 0.799 0.586 -0.889
ENSG00000137822 E006 4.3956563 0.0036302036 1.758984e-01 0.4867718767 15 43376098 43376226 129 + 0.785 0.620 -0.685
ENSG00000137822 E007 0.1316618 0.0124460908 3.150348e-01   15 43376455 43376502 48 + 0.000 0.120 11.324
ENSG00000137822 E008 1.6673021 0.0085467506 4.860100e-01 0.7719564588 15 43376503 43376539 37 + 0.461 0.356 -0.574
ENSG00000137822 E009 2.8248259 0.0050714904 7.912821e-02 0.3209750073 15 43376540 43376625 86 + 0.662 0.413 -1.178
ENSG00000137822 E010 2.4999714 0.0060767616 3.933666e-01 0.7065867693 15 43377014 43377067 54 + 0.584 0.463 -0.574
ENSG00000137822 E011 0.2461098 0.0164146680 6.903482e-01   15 43377598 43377846 249 + 0.075 0.120 0.748
ENSG00000137822 E012 2.3854854 0.0067152611 4.845008e-01 0.7709432388 15 43377847 43377891 45 + 0.562 0.463 -0.474
ENSG00000137822 E013 1.4210225 0.0169468731 3.657584e-01 0.6845590103 15 43377892 43377903 12 + 0.431 0.290 -0.837
ENSG00000137822 E014 3.0079364 0.0063270759 8.796283e-01 0.9619233845 15 43380084 43380163 80 + 0.605 0.586 -0.082
ENSG00000137822 E015 5.0618678 0.0027968219 1.802607e-02 0.1356388275 15 43383303 43383504 202 + 0.871 0.586 -1.169
ENSG00000137822 E016 0.2456120 0.0163578826 6.893074e-01   15 43385368 43385508 141 + 0.075 0.120 0.748
ENSG00000137822 E017 5.3689785 0.0069195239 9.479538e-04 0.0172457416 15 43385791 43385939 149 + 0.923 0.508 -1.730
ENSG00000137822 E018 3.0097742 0.1184901388 9.190083e-01 0.9764130188 15 43385940 43385956 17 + 0.605 0.586 -0.083
ENSG00000137822 E019 5.2799350 0.0029297664 6.351358e-01 0.8545658506 15 43386206 43386330 125 + 0.811 0.760 -0.203
ENSG00000137822 E020 0.7527910 0.0147252551 1.515550e-01 0.4505071514 15 43394081 43395106 1026 + 0.139 0.356 1.748
ENSG00000137822 E021 2.9091458 0.0126703074 6.785781e-01 0.8761830220 15 43395107 43395157 51 + 0.562 0.620 0.263
ENSG00000137822 E022 0.2623781 0.0163894862 1.111485e-01   15 43395158 43395582 425 + 0.000 0.213 12.209
ENSG00000137822 E023 3.5951237 0.0039871812 6.372411e-01 0.8557719940 15 43395583 43395688 106 + 0.679 0.620 -0.252
ENSG00000137822 E024 0.0000000       15 43397210 43397213 4 +      
ENSG00000137822 E025 4.7732276 0.0034082569 3.187647e-01 0.6440943523 15 43397214 43397321 108 + 0.799 0.682 -0.474
ENSG00000137822 E026 0.9298209 0.0224500270 1.206282e-01 0.4019628885 15 43398038 43398040 3 + 0.366 0.120 -2.059
ENSG00000137822 E027 3.1221749 0.0049225999 7.639480e-01 0.9162766438 15 43398041 43398129 89 + 0.624 0.586 -0.169
ENSG00000137822 E028 3.5952821 0.0042753719 6.387657e-01 0.8566902934 15 43398130 43398179 50 + 0.679 0.620 -0.252
ENSG00000137822 E029 0.1138060 0.0114258591 1.000000e+00   15 43398180 43398383 204 + 0.075 0.000 -11.130
ENSG00000137822 E030 1.3929607 0.0096315610 1.838179e-02 0.1373607802 15 43399112 43399174 63 + 0.195 0.549 2.163
ENSG00000137822 E031 8.4960048 0.0016845579 3.590796e-01 0.6788980706 15 43400044 43400221 178 + 1.003 0.919 -0.313
ENSG00000137822 E032 4.7397256 0.0034443337 4.287976e-01 0.7325150657 15 43401716 43401805 90 + 0.712 0.806 0.376
ENSG00000137822 E033 1.6195553 0.0095636204 8.143915e-02 0.3264316688 15 43401806 43401817 12 + 0.289 0.549 1.426
ENSG00000137822 E034 1.3581878 0.0098837899 2.545903e-01 0.5814924860 15 43401818 43401850 33 + 0.289 0.463 1.011
ENSG00000137822 E035 1.9655578 0.0237304096 3.170937e-01 0.6425879699 15 43401851 43403682 1832 + 0.400 0.549 0.748
ENSG00000137822 E036 0.0000000       15 43403683 43403799 117 +      
ENSG00000137822 E037 0.0000000       15 43403800 43403842 43 +      
ENSG00000137822 E038 0.0000000       15 43404413 43404552 140 +      
ENSG00000137822 E039 0.0000000       15 43405202 43406600 1399 +      
ENSG00000137822 E040 27.0505667 0.0008101146 2.024478e-06 0.0001048835 15 43406601 43409771 3171 + 1.327 1.566 0.827

Help

Please Click HERE to learn more details about the results from DEXseq.