ENSG00000138758

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264893 ENSG00000138758 No_inf pgwt_inf SEPTIN11 protein_coding protein_coding 28.99101 21.54567 30.34026 0.8705059 2.183166 0.4936412 20.6431340 13.697012 22.3644129 0.4160818 0.5945564 0.7069358 0.70915000 0.637100 0.748725 0.111625 0.992847247 0.003291381 FALSE  
ENST00000502401 ENSG00000138758 No_inf pgwt_inf SEPTIN11 protein_coding protein_coding 28.99101 21.54567 30.34026 0.8705059 2.183166 0.4936412 1.5305682 1.558137 0.6223946 0.5941755 0.3600550 -1.3101544 0.05321667 0.069250 0.023150 -0.046100 0.992847247 0.003291381    
ENST00000502584 ENSG00000138758 No_inf pgwt_inf SEPTIN11 protein_coding protein_coding 28.99101 21.54567 30.34026 0.8705059 2.183166 0.4936412 2.7453141 3.307051 2.0284498 0.2224248 0.1968280 -0.7024289 0.10129167 0.154425 0.067100 -0.087325 0.856587386 0.003291381 FALSE  
ENST00000512575 ENSG00000138758 No_inf pgwt_inf SEPTIN11 protein_coding protein_coding_CDS_not_defined 28.99101 21.54567 30.34026 0.8705059 2.183166 0.4936412 2.0005220 0.000000 3.6836380 0.0000000 2.2116147 8.5288987 0.05765833 0.000000 0.108550 0.108550 0.989910066 0.003291381    
ENST00000513373 ENSG00000138758 No_inf pgwt_inf SEPTIN11 protein_coding protein_coding_CDS_not_defined 28.99101 21.54567 30.34026 0.8705059 2.183166 0.4936412 0.5828878 1.748663 0.0000000 0.3656964 0.0000000 -7.4583356 0.02692500 0.080775 0.000000 -0.080775 0.003291381 0.003291381    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000138758 E001 0.2285450 0.0153239688 4.288742e-01   4 76949751 76949751 1 + 0.143 0.000 -10.435
ENSG00000138758 E002 0.4569458 0.0158382368 1.140944e-01   4 76949752 76949765 14 + 0.251 0.000 -13.659
ENSG00000138758 E003 1.4039682 0.0096846960 9.063320e-02 3.455461e-01 4 76949766 76949808 43 + 0.471 0.208 -1.675
ENSG00000138758 E004 2.6158400 0.0084712850 2.423478e-01 5.686488e-01 4 76949809 76949835 27 + 0.616 0.453 -0.768
ENSG00000138758 E005 2.3874393 0.0174885972 4.001564e-01 7.117127e-01 4 76949836 76949836 1 + 0.573 0.453 -0.575
ENSG00000138758 E006 3.8088377 0.0099110012 1.964354e-01 5.132512e-01 4 76949837 76949861 25 + 0.740 0.575 -0.706
ENSG00000138758 E007 7.6161454 0.0079209586 7.246295e-02 3.056167e-01 4 76949862 76949930 69 + 1.000 0.814 -0.706
ENSG00000138758 E008 0.3600600 0.0166196726 8.920944e-01   4 76972390 76972590 201 + 0.143 0.116 -0.353
ENSG00000138758 E009 0.2623781 0.0161369991 1.268177e-01   4 76973010 76973070 61 + 0.000 0.208 12.703
ENSG00000138758 E010 0.1311489 0.0122563512 3.443560e-01   4 76974478 76974807 330 + 0.000 0.116 11.767
ENSG00000138758 E011 0.1316618 0.0122989854 3.443732e-01   4 76985024 76985123 100 + 0.000 0.116 11.766
ENSG00000138758 E012 0.0000000       4 76987788 76987808 21 +      
ENSG00000138758 E013 0.1315150 0.0123653086 3.442934e-01   4 76987809 76987870 62 + 0.000 0.116 11.766
ENSG00000138758 E014 0.7354552 0.0672673219 6.151290e-01 8.451074e-01 4 76995781 76995938 158 + 0.201 0.283 0.648
ENSG00000138758 E015 10.9879225 0.0219197511 1.357050e-01 4.267805e-01 4 76996425 76996539 115 + 1.131 0.981 -0.545
ENSG00000138758 E016 22.5991133 0.0162141636 3.256015e-01 6.499785e-01 4 77005601 77005796 196 + 1.396 1.327 -0.239
ENSG00000138758 E017 0.2453240 0.0164467399 7.382325e-01   4 77009780 77009987 208 + 0.078 0.116 0.647
ENSG00000138758 E018 23.7549152 0.0158877378 1.960965e-01 5.128546e-01 4 77011735 77011921 187 + 1.425 1.333 -0.320
ENSG00000138758 E019 7.1585702 0.0024473628 1.340768e-01 4.242709e-01 4 77014856 77014870 15 + 0.965 0.814 -0.575
ENSG00000138758 E020 18.8133066 0.0008953057 1.046928e-01 3.730264e-01 4 77014871 77015017 147 + 1.333 1.229 -0.366
ENSG00000138758 E021 17.2809642 0.0007996664 1.842790e-01 4.975888e-01 4 77019165 77019261 97 + 1.292 1.205 -0.308
ENSG00000138758 E022 9.9910424 0.0015702901 5.464117e-01 8.088904e-01 4 77020502 77020531 30 + 1.056 1.008 -0.174
ENSG00000138758 E023 19.6004894 0.0092750467 5.528102e-02 2.627730e-01 4 77020532 77020670 139 + 1.364 1.221 -0.500
ENSG00000138758 E024 3.6995266 0.0057330620 1.298672e-01 4.181951e-01 4 77020671 77021639 969 + 0.573 0.771 0.840
ENSG00000138758 E025 15.5970717 0.0008767075 9.751612e-01 9.957403e-01 4 77028629 77028716 88 + 1.211 1.221 0.034
ENSG00000138758 E026 16.1539172 0.0021421674 4.253300e-01 7.298638e-01 4 77028717 77028761 45 + 1.200 1.266 0.232
ENSG00000138758 E027 28.2733869 0.0012016321 3.146714e-01 6.406448e-01 4 77030783 77030896 114 + 1.482 1.432 -0.172
ENSG00000138758 E028 22.1579323 0.0006782041 7.040496e-02 3.009810e-01 4 77030897 77030970 74 + 1.402 1.294 -0.376
ENSG00000138758 E029 20.1606729 0.0007728936 1.172893e-10 1.368444e-08 4 77030971 77032158 1188 + 1.085 1.517 1.515
ENSG00000138758 E030 55.2360067 0.0004923472 5.172273e-03 5.961713e-02 4 77034497 77034923 427 + 1.787 1.680 -0.362
ENSG00000138758 E031 20.1729497 0.0035757934 2.180587e-01 5.412590e-01 4 77034924 77035020 97 + 1.353 1.274 -0.276
ENSG00000138758 E032 162.4352515 0.0002428524 5.416498e-01 8.060369e-01 4 77035021 77036769 1749 + 2.211 2.205 -0.018
ENSG00000138758 E033 11.5312175 0.0039139786 4.476423e-02 2.323154e-01 4 77036770 77036772 3 + 1.008 1.188 0.647
ENSG00000138758 E034 17.8095829 0.0012393758 1.144786e-01 3.908744e-01 4 77036773 77036837 65 + 1.216 1.333 0.410
ENSG00000138758 E035 212.5886422 0.0033332948 1.446297e-02 1.177759e-01 4 77036838 77038715 1878 + 2.294 2.363 0.232
ENSG00000138758 E036 1.8039039 0.0078934306 3.898053e-04 8.672760e-03 4 77039073 77039326 254 + 0.143 0.670 3.232
ENSG00000138758 E037 3.3775192 0.0047944335 1.662209e-08 1.378750e-06 4 77039743 77040384 642 + 0.143 0.922 4.232

Help

Please Click HERE to learn more details about the results from DEXseq.