ENSG00000138777

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341695 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding protein_coding 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 1.956088 2.699278 0.7750068 1.5935047 0.77500681 -1.7871313 0.04596667 0.077450 0.016075 -0.061375 0.929520819 0.009376355 FALSE TRUE
ENST00000351450 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding nonsense_mediated_decay 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 22.435849 14.107961 24.0833489 3.1695126 0.93592757 0.7711032 0.46015000 0.369375 0.464950 0.095575 0.992847247 0.009376355 FALSE TRUE
ENST00000432483 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding protein_coding 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 1.342926 0.000000 4.0287777 0.0000000 2.32800372 8.6577749 0.02458333 0.000000 0.073750 0.073750 0.992847247 0.009376355 FALSE TRUE
ENST00000457404 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding protein_coding_CDS_not_defined 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 7.565810 2.214746 14.7557245 2.2147460 0.79865773 2.7305396 0.14940833 0.059825 0.284750 0.224925 0.185564231 0.009376355 FALSE FALSE
ENST00000499847 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding retained_intron 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 3.060871 4.238487 2.1654218 2.5178684 2.16542182 -0.9656541 0.06241667 0.104250 0.035325 -0.068925 0.992847247 0.009376355 FALSE TRUE
ENST00000502833 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding protein_coding_CDS_not_defined 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 2.950876 0.000000 0.0000000 0.0000000 0.00000000 0.0000000 0.05754167 0.000000 0.000000 0.000000   0.009376355 FALSE TRUE
ENST00000509031 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding nonsense_mediated_decay 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 1.566563 4.699689 0.0000000 1.8847895 0.00000000 -8.8794879 0.04403333 0.132100 0.000000 -0.132100 0.188929217 0.009376355 FALSE TRUE
ENST00000513605 ENSG00000138777 No_inf pgwt_inf PPA2 protein_coding retained_intron 47.6538 37.41907 52.12532 2.718968 3.07235 0.4781018 1.757205 3.935413 0.4198893 0.1421818 0.09509538 -3.1981394 0.04420000 0.107550 0.008200 -0.099350 0.009376355 0.009376355   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000138777 E001 0.6215915 0.1929250650 5.893428e-01   4 105369077 105369242 166 - 0.163 0.253 0.794
ENSG00000138777 E002 3.6881675 0.0043430121 1.440514e-03 2.369623e-02 4 105369243 105369560 318 - 0.414 0.832 1.861
ENSG00000138777 E003 1.1302840 0.0117048600 2.296638e-01 5.551037e-01 4 105369561 105369564 4 - 0.226 0.412 1.209
ENSG00000138777 E004 26.7838112 0.0005460504 1.847076e-01 4.981146e-01 4 105369565 105369753 189 - 1.404 1.480 0.262
ENSG00000138777 E005 0.4915776 0.0162369044 8.911375e-01   4 105370246 105370280 35 - 0.163 0.184 0.209
ENSG00000138777 E006 19.5039882 0.0008457430 4.212716e-01 7.272241e-01 4 105370837 105370873 37 - 1.284 1.338 0.191
ENSG00000138777 E007 22.8535505 0.0005934420 8.811387e-01 9.624124e-01 4 105386567 105386612 46 - 1.372 1.383 0.039
ENSG00000138777 E008 14.0496254 0.0011459691 9.237734e-01 9.783574e-01 4 105386613 105386636 24 - 1.173 1.182 0.034
ENSG00000138777 E009 22.7014409 0.0007266266 9.364860e-01 9.827484e-01 4 105396249 105396325 77 - 1.376 1.374 -0.008
ENSG00000138777 E010 13.5766231 0.0011064203 7.969069e-01 9.300928e-01 4 105396326 105396334 9 - 1.152 1.175 0.079
ENSG00000138777 E011 0.0000000       4 105398304 105398867 564 -      
ENSG00000138777 E012 21.4436103 0.0073921811 5.407488e-01 8.053357e-01 4 105399037 105399078 42 - 1.328 1.374 0.160
ENSG00000138777 E013 28.8780470 0.0042352273 6.943523e-01 8.839321e-01 4 105399079 105399150 72 - 1.486 1.465 -0.072
ENSG00000138777 E014 16.5019749 0.0015096901 8.333642e-01 9.440076e-01 4 105399151 105399164 14 - 1.235 1.252 0.060
ENSG00000138777 E015 6.5589832 0.0021783627 2.375182e-08 1.904666e-06 4 105399165 105399736 572 - 0.450 1.091 2.636
ENSG00000138777 E016 2.1298086 0.0127662484 1.426564e-01 4.370164e-01 4 105405637 105405837 201 - 0.374 0.591 1.084
ENSG00000138777 E017 0.8676330 0.0130069416 5.775325e-01 8.255087e-01 4 105405838 105405948 111 - 0.226 0.312 0.624
ENSG00000138777 E018 0.1308632 0.0122055451 4.684144e-01   4 105423204 105423381 178 - 0.000 0.101 10.248
ENSG00000138777 E019 25.6495543 0.0006778992 3.158677e-01 6.417754e-01 4 105424196 105424248 53 - 1.452 1.397 -0.190
ENSG00000138777 E020 27.8416459 0.0034857697 4.219229e-01 7.277545e-01 4 105424249 105424322 74 - 1.434 1.484 0.171
ENSG00000138777 E021 16.2396596 0.0013971204 2.535016e-01 5.803849e-01 4 105437950 105437976 27 - 1.192 1.276 0.297
ENSG00000138777 E022 19.6773992 0.0064447083 3.548145e-01 6.748480e-01 4 105437977 105438014 38 - 1.346 1.283 -0.221
ENSG00000138777 E023 19.5035632 0.0007099165 8.620770e-03 8.408907e-02 4 105438015 105438036 22 - 1.388 1.218 -0.594
ENSG00000138777 E024 1.3921618 0.2755009031 1.683017e-01 4.750683e-01 4 105446202 105446382 181 - 0.226 0.492 1.625
ENSG00000138777 E025 34.2119676 0.0004035550 1.038082e-01 3.712043e-01 4 105446383 105446502 120 - 1.584 1.506 -0.266
ENSG00000138777 E026 0.0000000       4 105447995 105448093 99 -      
ENSG00000138777 E027 20.1872105 0.0010310218 4.108854e-01 7.194967e-01 4 105449350 105449403 54 - 1.350 1.300 -0.175
ENSG00000138777 E028 16.2902576 0.0008224446 4.482838e-01 7.466381e-01 4 105453598 105453642 45 - 1.263 1.211 -0.181
ENSG00000138777 E029 0.0000000       4 105453781 105453908 128 -      
ENSG00000138777 E030 0.1138060 0.0111445283 6.166936e-01   4 105456081 105456247 167 - 0.089 0.000 -10.032
ENSG00000138777 E031 0.2626639 0.0160085374 1.987428e-01   4 105456248 105456291 44 - 0.000 0.184 11.248
ENSG00000138777 E032 0.0000000       4 105456292 105456680 389 -      
ENSG00000138777 E033 9.5153641 0.0023220689 9.529439e-01 9.885553e-01 4 105456681 105456695 15 - 1.024 1.020 -0.013
ENSG00000138777 E034 11.8659964 0.0206141526 3.884755e-01 7.022266e-01 4 105456696 105456745 50 - 1.152 1.062 -0.327
ENSG00000138777 E035 0.2623781 0.0159955656 1.987678e-01   4 105473340 105473357 18 - 0.000 0.184 11.248
ENSG00000138777 E036 1.6393616 0.0085367301 1.020541e-01 3.681214e-01 4 105473358 105473775 418 - 0.281 0.528 1.379
ENSG00000138777 E037 16.3273827 0.0008708332 4.487733e-03 5.388731e-02 4 105473894 105474067 174 - 1.328 1.126 -0.712

Help

Please Click HERE to learn more details about the results from DEXseq.