ENSG00000138814

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323055 ENSG00000138814 No_inf pgwt_inf PPP3CA protein_coding protein_coding 45.5604 49.9078 42.38865 1.227381 0.9567713 -0.235536 9.590603 7.844145 11.0308358 1.587293 1.1957674 0.4913233 0.21324167 0.156425 0.259600 0.103175 0.99284725 0.02697913 FALSE TRUE
ENST00000394854 ENSG00000138814 No_inf pgwt_inf PPP3CA protein_coding protein_coding 45.5604 49.9078 42.38865 1.227381 0.9567713 -0.235536 15.031558 10.157853 16.1068097 2.165564 0.8159398 0.6645512 0.33853333 0.206325 0.381575 0.175250 0.93113964 0.02697913 FALSE TRUE
ENST00000512215 ENSG00000138814 No_inf pgwt_inf PPP3CA protein_coding protein_coding 45.5604 49.9078 42.38865 1.227381 0.9567713 -0.235536 6.281637 16.389736 0.7810333 1.258290 0.7810333 -4.3737903 0.12690000 0.327175 0.018275 -0.308900 0.02697913 0.02697913 FALSE TRUE
MSTRG.22108.4 ENSG00000138814 No_inf pgwt_inf PPP3CA protein_coding   45.5604 49.9078 42.38865 1.227381 0.9567713 -0.235536 1.500456 4.501369 0.0000000 4.501369 0.0000000 -8.8174214 0.02971667 0.089150 0.000000 -0.089150 0.99323661 0.02697913 FALSE TRUE
MSTRG.22108.5 ENSG00000138814 No_inf pgwt_inf PPP3CA protein_coding   45.5604 49.9078 42.38865 1.227381 0.9567713 -0.235536 13.082669 10.935642 14.3286139 3.750769 1.0171260 0.3895489 0.28993333 0.219200 0.337275 0.118075 0.99284725 0.02697913 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000138814 E001 0.0000000       4 101023409 101023417 9 -      
ENSG00000138814 E002 0.2633236 2.564905e-01 3.407788e-01   4 101023418 101023430 13 - 0.000 0.165 9.210
ENSG00000138814 E003 209.2354519 7.856744e-05 3.691841e-14 6.925268e-12 4 101023431 101024327 897 - 2.231 2.377 0.489
ENSG00000138814 E004 322.4549532 6.650565e-05 1.072960e-06 6.033808e-05 4 101024328 101025317 990 - 2.466 2.535 0.231
ENSG00000138814 E005 193.3329502 9.123124e-05 8.129755e-03 8.107623e-02 4 101025318 101026061 744 - 2.256 2.306 0.169
ENSG00000138814 E006 2.3126173 6.658389e-03 6.751098e-03 7.151917e-02 4 101029166 101029195 30 - 0.250 0.650 2.159
ENSG00000138814 E007 34.8627948 9.425570e-03 1.891747e-01 5.034687e-01 4 101032267 101032364 98 - 1.598 1.511 -0.295
ENSG00000138814 E008 32.3816541 2.908953e-03 9.628701e-01 9.912909e-01 4 101040482 101040566 85 - 1.524 1.518 -0.020
ENSG00000138814 E009 28.4685047 5.521823e-04 4.278564e-01 7.316409e-01 4 101061087 101061161 75 - 1.492 1.445 -0.163
ENSG00000138814 E010 41.3885811 4.265461e-04 1.325498e-01 4.218802e-01 4 101063232 101063357 126 - 1.663 1.590 -0.249
ENSG00000138814 E011 37.5870922 3.549276e-04 2.196168e-02 1.526634e-01 4 101080532 101080626 95 - 1.644 1.530 -0.388
ENSG00000138814 E012 15.3587912 9.554755e-04 1.004852e-01 3.652971e-01 4 101083186 101083194 9 - 1.276 1.152 -0.439
ENSG00000138814 E013 28.0288038 5.109759e-04 1.667471e-01 4.728622e-01 4 101083195 101083263 69 - 1.503 1.422 -0.277
ENSG00000138814 E014 30.6387913 4.476268e-04 4.268053e-02 2.269370e-01 4 101093776 101093867 92 - 1.556 1.445 -0.382
ENSG00000138814 E015 23.7598255 1.049614e-03 1.812747e-03 2.819028e-02 4 101093868 101093915 48 - 1.488 1.295 -0.669
ENSG00000138814 E016 21.7573266 1.828090e-02 5.873086e-02 2.720819e-01 4 101098367 101098417 51 - 1.438 1.274 -0.569
ENSG00000138814 E017 22.7380656 8.653930e-03 3.109721e-02 1.882571e-01 4 101098418 101098462 45 - 1.454 1.295 -0.551
ENSG00000138814 E018 18.8388024 1.891990e-03 2.275609e-02 1.565538e-01 4 101098463 101098512 50 - 1.377 1.218 -0.557
ENSG00000138814 E019 33.9028760 4.174552e-04 1.318846e-03 2.220634e-02 4 101099611 101099722 112 - 1.625 1.459 -0.569
ENSG00000138814 E020 0.0000000       4 101108074 101108161 88 -      
ENSG00000138814 E021 35.7586859 4.130843e-04 1.828544e-03 2.836153e-02 4 101108954 101109078 125 - 1.644 1.486 -0.538
ENSG00000138814 E022 0.0000000       4 101158170 101158319 150 -      
ENSG00000138814 E023 0.2448134 1.636980e-02 9.354912e-01   4 101171084 101171226 143 - 0.100 0.090 -0.163
ENSG00000138814 E024 39.3509873 3.874534e-04 2.989551e-04 7.102537e-03 4 101195916 101196116 201 - 1.692 1.518 -0.594
ENSG00000138814 E025 0.0000000       4 101230823 101230860 38 -      
ENSG00000138814 E026 62.7913253 3.883816e-03 1.337916e-05 5.459230e-04 4 101346739 101347479 741 - 1.902 1.703 -0.670
ENSG00000138814 E027 2.2098986 6.695551e-03 8.269501e-01 9.415033e-01 4 101347480 101347560 81 - 0.523 0.489 -0.163
ENSG00000138814 E028 0.0000000       4 101348233 101348289 57 -      

Help

Please Click HERE to learn more details about the results from DEXseq.