ENSG00000138964

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000415224 ENSG00000138964 No_inf pgwt_inf PARVG protein_coding protein_coding 94.75665 160.0033 65.92625 1.839591 2.679893 -1.279048 58.712752 86.81685 44.4055591 2.2607312 1.9316687 -0.967076 0.66214167 0.542650 0.674075 0.131425 0.99252816 0.03870547 TRUE TRUE
ENST00000417767 ENSG00000138964 No_inf pgwt_inf PARVG protein_coding protein_coding 94.75665 160.0033 65.92625 1.839591 2.679893 -1.279048 11.880648 21.84532 8.6266908 1.2340104 1.3180083 -1.339434 0.11852500 0.136400 0.130275 -0.006125 1.00000000 0.03870547 TRUE FALSE
ENST00000453888 ENSG00000138964 No_inf pgwt_inf PARVG protein_coding protein_coding_CDS_not_defined 94.75665 160.0033 65.92625 1.839591 2.679893 -1.279048 4.755108 14.00761 0.2577115 1.0074776 0.2577115 -5.710418 0.03054167 0.087425 0.004200 -0.083225 0.03870547 0.03870547 FALSE TRUE
ENST00000471836 ENSG00000138964 No_inf pgwt_inf PARVG protein_coding retained_intron 94.75665 160.0033 65.92625 1.839591 2.679893 -1.279048 6.596234 13.91906 4.1982091 0.8917448 1.0230353 -1.726819 0.05969167 0.087200 0.063300 -0.023900 0.99284725 0.03870547 FALSE FALSE
MSTRG.19555.8 ENSG00000138964 No_inf pgwt_inf PARVG protein_coding   94.75665 160.0033 65.92625 1.839591 2.679893 -1.279048 7.558129 14.04282 5.8747987 0.8400400 0.2466580 -1.255795 0.07503333 0.087825 0.089975 0.002150 1.00000000 0.03870547 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000138964 E001 0.1141751 1.113037e-02 0.219611310   22 44172956 44172983 28 + 0.136 0.000 -10.021
ENSG00000138964 E002 0.5070504 3.082946e-02 0.863792391   22 44172984 44173191 208 + 0.136 0.173 0.408
ENSG00000138964 E003 0.3938127 3.456890e-02 0.388318939   22 44180925 44181021 97 + 0.000 0.173 11.208
ENSG00000138964 E004 0.9015952 1.959047e-02 0.328867770 0.65284456 22 44181022 44181185 164 + 0.136 0.296 1.408
ENSG00000138964 E005 0.2446691 1.614339e-02 0.524319935   22 44181207 44181259 53 + 0.136 0.066 -1.177
ENSG00000138964 E006 0.0000000       22 44181336 44181344 9 +      
ENSG00000138964 E007 0.3759623 1.686044e-02 0.923948676   22 44181345 44181345 1 + 0.136 0.122 -0.177
ENSG00000138964 E008 5.0725403 2.822627e-03 0.078305927 0.31920858 22 44181346 44181370 25 + 0.882 0.676 -0.824
ENSG00000138964 E009 0.2283502 2.200457e-01 0.092061324   22 44181371 44181397 27 + 0.240 0.000 -12.236
ENSG00000138964 E010 0.4738082 2.038351e-02 0.072655793   22 44181398 44181399 2 + 0.323 0.066 -2.762
ENSG00000138964 E011 0.9465220 8.517277e-02 0.017313402 0.13223101 22 44181400 44181431 32 + 0.506 0.122 -2.762
ENSG00000138964 E012 19.3678093 5.428931e-03 0.413868134 0.72145602 22 44181432 44181738 307 + 1.217 1.280 0.225
ENSG00000138964 E013 7.0293443 1.261274e-02 0.628086782 0.85095087 22 44181739 44181741 3 + 0.903 0.847 -0.216
ENSG00000138964 E014 14.8698011 1.994327e-03 0.150857856 0.44938220 22 44181742 44181749 8 + 1.236 1.121 -0.408
ENSG00000138964 E015 38.0403789 2.697025e-03 0.070072925 0.30016068 22 44181750 44181860 111 + 1.614 1.515 -0.338
ENSG00000138964 E016 15.3559684 1.810093e-03 0.119240255 0.39942969 22 44181861 44181863 3 + 1.254 1.131 -0.434
ENSG00000138964 E017 13.6050340 1.162214e-03 0.126222971 0.41182484 22 44181864 44181917 54 + 1.207 1.082 -0.447
ENSG00000138964 E018 0.0000000       22 44183318 44183408 91 +      
ENSG00000138964 E019 0.0000000       22 44183409 44183419 11 +      
ENSG00000138964 E020 0.0000000       22 44183590 44184261 672 +      
ENSG00000138964 E021 0.0000000       22 44185526 44185807 282 +      
ENSG00000138964 E022 0.0000000       22 44185808 44185872 65 +      
ENSG00000138964 E023 0.0000000       22 44185873 44186576 704 +      
ENSG00000138964 E024 4.0026130 2.082848e-02 0.027811755 0.17641953 22 44186577 44187768 1192 + 0.393 0.732 1.578
ENSG00000138964 E025 4.9231534 6.202045e-03 0.003586267 0.04615702 22 44187769 44187775 7 + 0.393 0.815 1.910
ENSG00000138964 E026 57.1377881 2.581598e-04 0.313133520 0.63905144 22 44187776 44187878 103 + 1.686 1.729 0.147
ENSG00000138964 E027 28.1497104 5.275243e-04 0.134430755 0.42495342 22 44187879 44189113 1235 + 1.349 1.442 0.322
ENSG00000138964 E028 107.3014878 2.067809e-04 0.725553790 0.89946169 22 44189114 44189254 141 + 1.995 1.984 -0.038
ENSG00000138964 E029 100.3379025 1.681914e-04 0.263323324 0.59139015 22 44190551 44190666 116 + 1.984 1.948 -0.120
ENSG00000138964 E030 62.8804374 2.463013e-04 0.399078828 0.71111500 22 44192049 44192104 56 + 1.783 1.748 -0.116
ENSG00000138964 E031 0.3771270 1.664133e-02 0.922991620   22 44192105 44192129 25 + 0.136 0.122 -0.177
ENSG00000138964 E032 52.0149405 2.627520e-04 0.805563278 0.93349158 22 44193801 44193823 23 + 1.686 1.674 -0.039
ENSG00000138964 E033 0.3764752 1.660140e-02 0.923421625   22 44196098 44196154 57 + 0.136 0.122 -0.177
ENSG00000138964 E034 38.4355494 4.077898e-04 0.957668362 0.98946241 22 44196155 44196156 2 + 1.552 1.548 -0.011
ENSG00000138964 E035 78.5225826 2.190844e-04 0.989952888 1.00000000 22 44196157 44196213 57 + 1.853 1.853 0.000
ENSG00000138964 E036 86.7473499 2.061407e-04 0.858667797 0.95458736 22 44196347 44196415 69 + 1.892 1.898 0.019
ENSG00000138964 E037 1.7867109 7.967803e-03 0.441510481 0.74161579 22 44198606 44198620 15 + 0.323 0.446 0.697
ENSG00000138964 E038 99.0138066 1.112450e-03 0.775783894 0.92204777 22 44198621 44198722 102 + 1.946 1.955 0.032
ENSG00000138964 E039 80.5286932 1.911730e-04 0.180783111 0.49352339 22 44205757 44205829 73 + 1.898 1.850 -0.160
ENSG00000138964 E040 191.0692006 9.491849e-05 0.001482511 0.02417836 22 44206317 44210427 4111 + 2.183 2.255 0.241
ENSG00000138964 E041 0.0000000       22 44218491 44218773 283 +      
ENSG00000138964 E042 0.0000000       22 44219484 44219533 50 +      

Help

Please Click HERE to learn more details about the results from DEXseq.