ENSG00000139644

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000267115 ENSG00000139644 No_inf pgwt_inf TMBIM6 protein_coding protein_coding 284.9705 172.1927 344.2008 0.9248857 8.552623 0.9991852 234.96959 168.629 264.9404 0.8164584 2.062536 0.6517842 0.8517500 0.979375 0.771025 -0.20835 1.098276e-02 1.38149e-09 FALSE TRUE
ENST00000552635 ENSG00000139644 No_inf pgwt_inf TMBIM6 protein_coding nonsense_mediated_decay 284.9705 172.1927 344.2008 0.9248857 8.552623 0.9991852 40.36168 0.000 64.6429 0.0000000 8.621267 12.6584995 0.1166417 0.000000 0.186350 0.18635 1.381490e-09 1.38149e-09 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000139644 E001 0.0000000       12 49707725 49707732 8 +      
ENSG00000139644 E002 0.0000000       12 49707733 49707839 107 +      
ENSG00000139644 E003 0.1141751 1.116717e-02 0.9592877554   12 49715381 49715543 163 + 0.075 0.000 -11.299
ENSG00000139644 E004 0.0000000       12 49715544 49715777 234 +      
ENSG00000139644 E005 0.0000000       12 49738993 49739082 90 +      
ENSG00000139644 E006 0.0000000       12 49741202 49741329 128 +      
ENSG00000139644 E007 0.2625250 1.608310e-02 0.1142135334   12 49741544 49741546 3 + 0.000 0.214 13.938
ENSG00000139644 E008 0.2625250 1.608310e-02 0.1142135334   12 49741547 49741548 2 + 0.000 0.214 13.938
ENSG00000139644 E009 0.5079830 2.604597e-02 0.1397018052   12 49741549 49741556 8 + 0.075 0.291 2.336
ENSG00000139644 E010 6.2170759 2.289374e-03 0.2987686777 0.626285524 12 49741557 49741567 11 + 0.798 0.919 0.467
ENSG00000139644 E011 7.2152743 1.958943e-03 0.1391011054 0.431932691 12 49741568 49741570 3 + 0.836 0.995 0.604
ENSG00000139644 E012 10.8248584 1.480907e-03 0.2582826756 0.586073696 12 49741571 49741573 3 + 1.019 1.127 0.392
ENSG00000139644 E013 76.7901824 2.068332e-03 0.8665932680 0.957538303 12 49741574 49741607 34 + 1.881 1.886 0.015
ENSG00000139644 E014 78.9498204 1.220933e-03 0.8191720408 0.938228889 12 49741608 49741611 4 + 1.894 1.897 0.008
ENSG00000139644 E015 0.2279004 2.396459e-01 0.5227900419   12 49741612 49741768 157 + 0.139 0.000 -12.942
ENSG00000139644 E016 0.0000000       12 49741809 49741821 13 +      
ENSG00000139644 E017 0.2450383 1.637656e-02 0.7002087825   12 49741822 49741951 130 + 0.075 0.120 0.751
ENSG00000139644 E018 0.2450383 1.637656e-02 0.7002087825   12 49741952 49741956 5 + 0.075 0.120 0.751
ENSG00000139644 E019 4.9981446 2.941440e-03 0.2109784908 0.532256000 12 49741957 49742115 159 + 0.824 0.682 -0.571
ENSG00000139644 E020 0.3936739 1.590123e-02 0.0377957349   12 49742116 49742280 165 + 0.000 0.291 14.521
ENSG00000139644 E021 0.1316618 1.228315e-02 0.3204837632   12 49742281 49742437 157 + 0.000 0.120 13.023
ENSG00000139644 E022 0.1138060 1.114625e-02 0.9592798435   12 49742438 49742607 170 + 0.075 0.000 -12.888
ENSG00000139644 E023 0.0000000       12 49743417 49743565 149 +      
ENSG00000139644 E024 0.3415621 3.073435e-02 0.2429893726   12 49744413 49744542 130 + 0.195 0.000 -14.123
ENSG00000139644 E025 0.2284008 1.538718e-02 0.4646928738   12 49749618 49749734 117 + 0.139 0.000 -13.779
ENSG00000139644 E026 0.4741571 2.283850e-02 0.6141673744   12 49749735 49749856 122 + 0.195 0.120 -0.834
ENSG00000139644 E027 0.1141751 1.116717e-02 0.9592877554   12 49750620 49750705 86 + 0.075 0.000 -12.887
ENSG00000139644 E028 0.1141751 1.116717e-02 0.9592877554   12 49752456 49752463 8 + 0.075 0.000 -12.887
ENSG00000139644 E029 83.2143970 2.898828e-03 0.6052832597 0.840010120 12 49752464 49752465 2 + 1.922 1.912 -0.032
ENSG00000139644 E030 159.4143085 1.115945e-04 0.0759179799 0.313267150 12 49752466 49752549 84 + 2.211 2.178 -0.109
ENSG00000139644 E031 0.2279004 2.396459e-01 0.5227900419   12 49752964 49752972 9 + 0.139 0.000 -12.942
ENSG00000139644 E032 150.1496214 1.034585e-04 0.0005643248 0.011544411 12 49752973 49753037 65 + 2.201 2.124 -0.258
ENSG00000139644 E033 156.2797201 1.099871e-04 0.0001320743 0.003680469 12 49753038 49753081 44 + 2.221 2.136 -0.284
ENSG00000139644 E034 290.0517863 9.290220e-04 0.0335213769 0.196625388 12 49755635 49755755 121 + 2.470 2.435 -0.118
ENSG00000139644 E035 0.3774055 1.665682e-02 0.3226823210   12 49755756 49755756 1 + 0.075 0.214 1.751
ENSG00000139644 E036 0.2628107 1.608508e-02 0.1142172167   12 49758207 49758226 20 + 0.000 0.214 13.938
ENSG00000139644 E037 177.7623729 1.062662e-04 0.6441537149 0.859502454 12 49758227 49758275 49 + 2.244 2.245 0.001
ENSG00000139644 E038 0.8170058 2.679646e-02 0.1796930459 0.492065668 12 49758352 49758382 31 + 0.329 0.120 -1.834
ENSG00000139644 E039 230.3162672 8.478114e-05 0.8009697247 0.931747098 12 49758383 49758480 98 + 2.354 2.360 0.019
ENSG00000139644 E040 0.4907892 1.594432e-02 0.6240333190   12 49758481 49758682 202 + 0.139 0.214 0.751
ENSG00000139644 E041 196.3043299 6.836094e-04 0.8323640749 0.943740614 12 49758683 49758762 80 + 2.285 2.291 0.019
ENSG00000139644 E042 1.0505245 1.156072e-02 0.0002046741 0.005208690 12 49758804 49759135 332 + 0.000 0.549 16.003
ENSG00000139644 E043 0.7362369 5.889212e-02 0.5639359035 0.817998289 12 49759136 49759220 85 + 0.195 0.291 0.750
ENSG00000139644 E044 241.8972974 4.756578e-04 0.6673100153 0.870961720 12 49759221 49759321 101 + 2.377 2.379 0.006
ENSG00000139644 E045 222.5606183 8.924333e-05 0.2992375190 0.626639958 12 49761704 49761779 76 + 2.328 2.360 0.107
ENSG00000139644 E046 1.4362135 1.215149e-01 0.8381100505 0.946096576 12 49761780 49762137 358 + 0.400 0.356 -0.249
ENSG00000139644 E047 2248.2479974 8.910976e-04 0.0055990317 0.062660785 12 49762873 49764934 2062 + 3.331 3.363 0.108

Help

Please Click HERE to learn more details about the results from DEXseq.