ENSG00000140464

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000268058 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 2.5263801 5.2272756 0.0000000 0.2780986 0.0000000 -9.0326727 0.14736667 0.301575 0.000000 -0.301575 1.973070e-06 1.97307e-06 FALSE TRUE
ENST00000268059 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 2.6952822 1.9943453 3.1617929 1.9943453 1.8298974 0.6621675 0.14689167 0.121800 0.151400 0.029600 9.928472e-01 1.97307e-06 FALSE TRUE
ENST00000354026 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 1.6325654 2.4733518 0.9450578 1.7051965 0.9450578 -1.3786286 0.09046667 0.139975 0.037025 -0.102950 9.928472e-01 1.97307e-06 FALSE TRUE
ENST00000395135 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 1.1121807 0.2429902 1.4428793 0.2429902 1.4428793 2.5217615 0.05568333 0.014150 0.056525 0.042375 1.000000e+00 1.97307e-06 FALSE TRUE
ENST00000436891 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 0.4829734 0.0000000 1.4489203 0.0000000 1.4489203 7.1887572 0.02129167 0.000000 0.063875 0.063875 9.932366e-01 1.97307e-06 FALSE TRUE
ENST00000562086 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 2.2002294 1.5916350 3.2742915 0.5386388 0.5633477 1.0360368 0.11396667 0.093000 0.149850 0.056850 9.928472e-01 1.97307e-06 FALSE TRUE
ENST00000564428 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 1.7969305 0.4449353 3.3840413 0.4449353 1.2348312 2.8992707 0.09045000 0.024675 0.158025 0.133350 8.351149e-01 1.97307e-06 FALSE TRUE
ENST00000565898 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 2.4326318 0.0000000 4.9143313 0.0000000 0.2441280 8.9437840 0.11821667 0.000000 0.219925 0.219925 6.190336e-05 1.97307e-06 FALSE TRUE
ENST00000567606 ENSG00000140464 No_inf pgwt_inf PML protein_coding protein_coding 19.03428 17.35894 22.48615 0.3780341 1.124919 0.3731681 2.3351295 2.9138686 1.8788872 1.7785851 1.0848044 -0.6303419 0.12165833 0.164675 0.078200 -0.086475 1.000000e+00 1.97307e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000140464 E001 0.0000000       15 73994673 73994715 43 +      
ENSG00000140464 E002 0.0000000       15 73994716 73994716 1 +      
ENSG00000140464 E003 0.2457437 0.0162039908 0.9367371790   15 73994717 73994728 12 + 0.091 0.099 0.134
ENSG00000140464 E004 0.2457437 0.0162039908 0.9367371790   15 73994729 73994730 2 + 0.091 0.099 0.134
ENSG00000140464 E005 0.3774055 0.0166267697 0.5228066946   15 73994731 73994732 2 + 0.091 0.180 1.134
ENSG00000140464 E006 0.4915806 0.0158624612 0.9192834847   15 73994733 73994743 11 + 0.167 0.180 0.134
ENSG00000140464 E007 3.5348168 0.0043073107 0.7787687903 0.923282947 15 73994744 73994802 59 + 0.676 0.637 -0.165
ENSG00000140464 E008 6.3325195 0.0367383020 0.7111911252 0.892724133 15 73994803 73994941 139 + 0.891 0.839 -0.200
ENSG00000140464 E009 3.6326427 0.0480628084 0.4870962751 0.772702438 15 73998004 73998023 20 + 0.717 0.610 -0.451
ENSG00000140464 E010 38.7130480 0.0073802101 0.0206206611 0.146871329 15 73998024 73998476 453 + 1.662 1.529 -0.451
ENSG00000140464 E011 11.5782577 0.0012459408 0.6671299909 0.870902808 15 74022828 74022904 77 + 1.119 1.080 -0.140
ENSG00000140464 E012 5.4957462 0.0026063460 0.9148836459 0.974781495 15 74022905 74022911 7 + 0.820 0.805 -0.058
ENSG00000140464 E013 7.8361615 0.0018106553 0.8777127992 0.961329788 15 74022912 74022980 69 + 0.940 0.952 0.044
ENSG00000140464 E014 26.9202030 0.0006432551 0.0667581159 0.292426879 15 74022981 74023294 314 + 1.497 1.391 -0.365
ENSG00000140464 E015 10.7859045 0.0111604577 0.7950225612 0.929370380 15 74023295 74023365 71 + 1.061 1.080 0.068
ENSG00000140464 E016 9.8868651 0.0064280122 0.7690305485 0.918820297 15 74023366 74023408 43 + 1.052 1.021 -0.116
ENSG00000140464 E017 9.8060144 0.0024790347 0.8154982663 0.937051362 15 74024857 74024879 23 + 1.025 1.041 0.062
ENSG00000140464 E018 10.7185763 0.0014034014 0.5561809947 0.814247381 15 74024880 74024927 48 + 1.095 1.041 -0.195
ENSG00000140464 E019 11.3302842 0.0013151146 0.0130092895 0.109991393 15 74024928 74028442 3515 + 0.974 1.179 0.746
ENSG00000140464 E020 0.6216493 0.0156446203 0.5777200353   15 74032395 74032571 177 + 0.167 0.248 0.719
ENSG00000140464 E021 6.9235297 0.0020746823 0.2390581693 0.564882132 15 74032572 74032698 127 + 0.835 0.952 0.444
ENSG00000140464 E022 1.8154363 0.0081987352 0.5677559789 0.819796791 15 74032699 74032715 17 + 0.492 0.405 -0.451
ENSG00000140464 E023 25.2173253 0.0005697843 0.0711927830 0.302807474 15 74033156 74033414 259 + 1.470 1.363 -0.370
ENSG00000140464 E024 0.3423004 0.0240114382 0.1254649824   15 74033415 74033422 8 + 0.231 0.000 -9.906
ENSG00000140464 E025 1.3753054 0.0099310571 0.2874241847 0.615014980 15 74033423 74034477 1055 + 0.287 0.446 0.942
ENSG00000140464 E026 7.1911250 0.0020294958 0.0274341856 0.174938434 15 74034478 74034530 53 + 1.015 0.787 -0.866
ENSG00000140464 E027 9.2396436 0.0019161532 0.4809974802 0.768511319 15 74034531 74035131 601 + 1.043 0.976 -0.248
ENSG00000140464 E028 1.1929247 0.1178270025 0.3375179983 0.660184579 15 74035132 74035142 11 + 0.421 0.248 -1.088
ENSG00000140464 E029 1.8963520 0.0076374254 0.0681190870 0.295873822 15 74035143 74035171 29 + 0.580 0.307 -1.451
ENSG00000140464 E030 60.6496474 0.0002400910 0.9679670850 0.993244432 15 74035172 74036006 835 + 1.792 1.787 -0.017
ENSG00000140464 E031 6.8716487 0.0020352727 0.7055640638 0.889920183 15 74036007 74036034 28 + 0.878 0.913 0.134
ENSG00000140464 E032 21.6810213 0.0007213877 0.1488699623 0.445988195 15 74036035 74036394 360 + 1.310 1.395 0.298
ENSG00000140464 E033 0.0000000       15 74041329 74041570 242 +      
ENSG00000140464 E034 0.0000000       15 74042989 74043139 151 +      
ENSG00000140464 E035 0.0000000       15 74043140 74043342 203 +      
ENSG00000140464 E036 101.8301273 0.0001740407 0.0001426457 0.003917479 15 74044221 74047827 3607 + 1.960 2.056 0.323

Help

Please Click HERE to learn more details about the results from DEXseq.