ENSG00000141968

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000539284 ENSG00000141968 No_inf pgwt_inf VAV1 protein_coding protein_coding 74.70922 53.48404 86.85553 1.997648 0.8441188 0.6994057 23.586136 23.092051 24.28892 1.0386060 3.987945 0.07287104 0.33049167 0.431550 0.278475 -0.153075 0.9716538398 0.0001440736 FALSE  
ENST00000596764 ENSG00000141968 No_inf pgwt_inf VAV1 protein_coding protein_coding 74.70922 53.48404 86.85553 1.997648 0.8441188 0.6994057 6.837811 3.609011 11.27362 0.9881698 3.573176 1.64056296 0.08868333 0.068025 0.129775 0.061750 0.9928472467 0.0001440736 FALSE  
ENST00000601452 ENSG00000141968 No_inf pgwt_inf VAV1 protein_coding retained_intron 74.70922 53.48404 86.85553 1.997648 0.8441188 0.6994057 1.498470 3.206856 0.00000 0.7754867 0.000000 -8.32950740 0.02524167 0.060050 0.000000 -0.060050 0.0001440736 0.0001440736 FALSE  
ENST00000602142 ENSG00000141968 No_inf pgwt_inf VAV1 protein_coding protein_coding 74.70922 53.48404 86.85553 1.997648 0.8441188 0.6994057 40.071595 20.843705 48.55480 1.3512196 3.134911 1.21960719 0.51814167 0.391150 0.559900 0.168750 0.9719904703 0.0001440736 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000141968 E001 0.0000000       19 6772708 6772713 6 +      
ENSG00000141968 E002 0.2279811 0.0154176481 4.906919e-01   19 6772714 6772727 14 + 0.138 0.000 -11.563
ENSG00000141968 E003 0.3421562 0.0304237486 2.597506e-01   19 6772728 6772746 19 + 0.193 0.000 -12.146
ENSG00000141968 E004 46.9103436 0.0003068925 8.548907e-03 0.0835623786 19 6772747 6773011 265 + 1.716 1.596 -0.407
ENSG00000141968 E005 0.1138060 0.0112140944 1.000000e+00   19 6784118 6784241 124 + 0.074 0.000 -10.561
ENSG00000141968 E006 0.0000000       19 6816436 6816471 36 +      
ENSG00000141968 E007 45.0192767 0.0003373741 9.435996e-02 0.3530832960 19 6820702 6820818 117 + 1.684 1.607 -0.262
ENSG00000141968 E008 32.6295517 0.0019237901 7.763131e-02 0.3175964697 19 6821622 6821680 59 + 1.556 1.456 -0.342
ENSG00000141968 E009 36.5473360 0.0004332407 6.354647e-01 0.8547465098 19 6821791 6821859 69 + 1.576 1.552 -0.081
ENSG00000141968 E010 53.3887231 0.0005048678 5.863032e-01 0.8303538399 19 6822221 6822329 109 + 1.736 1.713 -0.077
ENSG00000141968 E011 22.9049495 0.0005870642 8.803613e-01 0.9621065046 19 6822419 6822436 18 + 1.366 1.376 0.034
ENSG00000141968 E012 43.4452482 0.0006603076 6.369293e-01 0.8555675902 19 6822437 6822514 78 + 1.630 1.653 0.076
ENSG00000141968 E013 44.0655999 0.0009961388 9.823074e-02 0.3613273884 19 6825053 6825121 69 + 1.675 1.596 -0.268
ENSG00000141968 E014 47.6602125 0.0003145712 8.137654e-02 0.3263634935 19 6825303 6825406 104 + 1.708 1.630 -0.265
ENSG00000141968 E015 49.0679837 0.0003089823 8.314260e-01 0.9434209311 19 6826612 6826711 100 + 1.687 1.697 0.032
ENSG00000141968 E016 0.4557372 0.0162259666 1.403089e-01   19 6826712 6827104 393 + 0.242 0.000 -12.561
ENSG00000141968 E017 51.5153026 0.0019681828 8.072142e-01 0.9342003741 19 6828076 6828171 96 + 1.716 1.705 -0.038
ENSG00000141968 E018 1.2091782 0.0144631704 8.410204e-01 0.9474476562 19 6828315 6828418 104 + 0.327 0.358 0.194
ENSG00000141968 E019 30.9427212 0.0240544166 4.916774e-01 0.7752520086 19 6828419 6828445 27 + 1.518 1.461 -0.197
ENSG00000141968 E020 30.4399295 0.0264991652 8.604785e-01 0.9550786502 19 6828446 6828461 16 + 1.495 1.480 -0.054
ENSG00000141968 E021 37.8761510 0.0153877226 7.401621e-01 0.9061378546 19 6828462 6828487 26 + 1.591 1.567 -0.080
ENSG00000141968 E022 2.5739669 0.0056461774 1.106236e-05 0.0004646016 19 6828488 6828621 134 + 0.193 0.810 3.281
ENSG00000141968 E023 56.0172448 0.0034643827 5.637914e-01 0.8179174210 19 6828622 6828708 87 + 1.758 1.732 -0.089
ENSG00000141968 E024 55.0379879 0.0002586037 9.718049e-01 0.9947405239 19 6828815 6828900 86 + 1.740 1.739 -0.004
ENSG00000141968 E025 47.7555978 0.0031706010 7.660421e-01 0.9171100445 19 6829786 6829872 87 + 1.674 1.688 0.050
ENSG00000141968 E026 41.3686068 0.0167226666 2.224165e-01 0.5465610521 19 6829873 6829918 46 + 1.582 1.668 0.292
ENSG00000141968 E027 61.0055626 0.0080578719 4.963816e-01 0.7779556630 19 6832091 6832200 110 + 1.769 1.805 0.122
ENSG00000141968 E028 54.1750646 0.0004741168 8.622321e-01 0.9557742167 19 6833184 6833285 102 + 1.736 1.729 -0.023
ENSG00000141968 E029 53.6661166 0.0002664141 7.445405e-01 0.9083626222 19 6833528 6833625 98 + 1.735 1.721 -0.045
ENSG00000141968 E030 31.0430148 0.0004232843 7.920781e-01 0.9283405867 19 6833711 6833733 23 + 1.503 1.489 -0.048
ENSG00000141968 E031 41.1072014 0.0003165837 3.274047e-01 0.6518134968 19 6833908 6833953 46 + 1.597 1.643 0.158
ENSG00000141968 E032 0.7190511 0.0135048603 8.587387e-01 0.9545873590 19 6835809 6836431 623 + 0.242 0.215 -0.221
ENSG00000141968 E033 71.0843848 0.0005264616 6.748966e-02 0.2942232313 19 6836432 6836568 137 + 1.821 1.888 0.227
ENSG00000141968 E034 51.0237905 0.0003193619 3.335227e-01 0.6568668380 19 6836985 6837050 66 + 1.724 1.683 -0.140
ENSG00000141968 E035 40.1248237 0.0020255289 5.195479e-01 0.7922307807 19 6843135 6843166 32 + 1.619 1.586 -0.112
ENSG00000141968 E036 91.7919462 0.0001622771 2.859503e-01 0.6134554759 19 6847998 6848114 117 + 1.945 1.979 0.114
ENSG00000141968 E037 93.0973875 0.0001713409 1.026072e-02 0.0943204540 19 6850670 6850757 88 + 1.931 2.011 0.270
ENSG00000141968 E038 88.4513113 0.0001898815 4.878322e-01 0.7732543279 19 6852965 6853079 115 + 1.934 1.957 0.076
ENSG00000141968 E039 108.2703009 0.0030337802 9.894221e-01 1.0000000000 19 6853947 6854098 152 + 2.030 2.030 0.000
ENSG00000141968 E040 112.3540049 0.0012362387 4.134998e-01 0.7213385261 19 6857054 6857366 313 + 2.035 2.061 0.087

Help

Please Click HERE to learn more details about the results from DEXseq.