ENSG00000143622

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000368322 ENSG00000143622 No_inf pgwt_inf RIT1 protein_coding protein_coding 29.79005 21.9116 34.54041 0.5379451 1.925707 0.6563499 5.8508880 0.000000 9.1315037 0.0000000 2.9279001 9.83628768 0.17495000 0.000000 0.261625 0.261625 0.0002626886 0.0002626886 FALSE TRUE
ENST00000368323 ENSG00000143622 No_inf pgwt_inf RIT1 protein_coding protein_coding 29.79005 21.9116 34.54041 0.5379451 1.925707 0.6563499 15.6713434 14.695721 14.7358768 0.6463918 0.5007887 0.00393408 0.54652500 0.672050 0.428975 -0.243075 0.6917260130 0.0002626886 FALSE TRUE
ENST00000539040 ENSG00000143622 No_inf pgwt_inf RIT1 protein_coding protein_coding 29.79005 21.9116 34.54041 0.5379451 1.925707 0.6563499 1.8905262 1.775749 1.6534008 1.0291560 0.9755029 -0.10239316 0.06315000 0.081900 0.044275 -0.037625 1.0000000000 0.0002626886 FALSE TRUE
ENST00000704061 ENSG00000143622 No_inf pgwt_inf RIT1 protein_coding nonsense_mediated_decay 29.79005 21.9116 34.54041 0.5379451 1.925707 0.6563499 0.8709643 2.339570 0.2733226 1.3539558 0.2733226 -3.05187920 0.03763333 0.105675 0.007225 -0.098450 0.9928472467 0.0002626886 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000143622 E001 68.4104294 0.0004886784 1.083148e-03 0.0190586599 1 155897808 155898768 961 - 1.783 1.895 0.377
ENSG00000143622 E002 6.3286244 0.0023925692 8.615898e-01 0.9554701209 1 155898769 155898801 33 - 0.874 0.855 -0.072
ENSG00000143622 E003 7.7573212 0.0017928758 2.722211e-01 0.6003545295 1 155898802 155898836 35 - 0.887 0.993 0.400
ENSG00000143622 E004 11.4527863 0.0422378242 9.840016e-01 0.9989830237 1 155898837 155898911 75 - 1.101 1.089 -0.046
ENSG00000143622 E005 146.3511107 0.0001208863 3.650820e-06 0.0001757094 1 155898912 155900273 1362 - 2.119 2.214 0.319
ENSG00000143622 E006 53.4119107 0.0015413459 1.849991e-01 0.4985209320 1 155900274 155900593 320 - 1.762 1.707 -0.187
ENSG00000143622 E007 11.1802297 0.0012814699 5.174211e-02 0.2528993044 1 155900594 155900618 25 - 1.159 0.993 -0.600
ENSG00000143622 E008 16.1133807 0.0010344741 2.341860e-02 0.1589769484 1 155904311 155904373 63 - 1.306 1.142 -0.578
ENSG00000143622 E009 29.8475503 0.0006738754 4.604456e-02 0.2360067340 1 155904374 155904502 129 - 1.538 1.432 -0.366
ENSG00000143622 E010 0.3592737 0.1467420890 7.306886e-01   1 155904603 155904605 3 - 0.160 0.103 -0.737
ENSG00000143622 E011 0.3592737 0.1467420890 7.306886e-01   1 155904606 155904610 5 - 0.160 0.103 -0.737
ENSG00000143622 E012 1.1463917 0.0267176106 5.382539e-02 0.2591017867 1 155904612 155904730 119 - 0.160 0.459 2.070
ENSG00000143622 E013 17.6546708 0.0009050559 1.604003e-01 0.4633011648 1 155904731 155904804 74 - 1.315 1.219 -0.339
ENSG00000143622 E014 1.3079418 0.0102374879 2.209229e-01 0.5447108892 1 155910095 155910449 355 - 0.445 0.256 -1.152
ENSG00000143622 E015 17.0057203 0.0008382400 5.755093e-02 0.2685608855 1 155910450 155910506 57 - 1.315 1.182 -0.469
ENSG00000143622 E016 24.1614448 0.0005857769 3.127083e-03 0.0419414741 1 155910656 155910804 149 - 1.478 1.302 -0.610
ENSG00000143622 E017 1.2291363 0.0224658393 7.777107e-01 0.9227113745 1 155910805 155910877 73 - 0.326 0.369 0.263
ENSG00000143622 E018 0.9666015 0.0139247060 6.548901e-01 0.8654623619 1 155910878 155910918 41 - 0.326 0.256 -0.474
ENSG00000143622 E019 9.6268533 0.0016447689 9.702404e-02 0.3587639415 1 155911243 155911271 29 - 1.093 0.943 -0.552
ENSG00000143622 E020 9.1523280 0.0015125415 1.297814e-01 0.4180313418 1 155911272 155911404 133 - 1.069 0.930 -0.515

Help

Please Click HERE to learn more details about the results from DEXseq.