ENSG00000144283

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000389757 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding protein_coding 21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 2.1889916 3.0318138 1.0939631 1.3063135 1.0939631 -1.462240 0.08766667 0.116050 0.023425 -0.092625 0.9519233510 0.0009736898 FALSE TRUE
ENST00000389759 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding protein_coding 21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.0275128 0.0000000 0.6530830 0.0000000 0.6530830 6.051117 0.06620833 0.000000 0.034550 0.034550 0.9928472467 0.0009736898 FALSE TRUE
ENST00000426248 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding nonsense_mediated_decay 21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 0.6256848 0.0000000 1.3194316 0.0000000 0.5770876 7.054666 0.04490000 0.000000 0.089725 0.089725 0.3760827906 0.0009736898 FALSE TRUE
ENST00000480171 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding retained_intron 21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.0835986 3.2507958 0.0000000 0.2006552 0.0000000 -8.349080 0.04207500 0.126225 0.000000 -0.126225 0.0009736898 0.0009736898 FALSE TRUE
ENST00000483881 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding retained_intron 21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 0.7780932 0.0000000 1.7208400 0.0000000 1.7208400 7.435329 0.04068333 0.000000 0.091025 0.091025 0.9928472467 0.0009736898 FALSE FALSE
ENST00000486254 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding retained_intron 21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.1714605 2.2499531 0.1349031 0.7037796 0.0779938 -3.963132 0.05609167 0.090475 0.005100 -0.085375 0.3278351306 0.0009736898 FALSE TRUE
ENST00000492496 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding retained_intron 21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.2972702 1.9416821 0.6639077 0.7040863 0.4074962 -1.534095 0.06167500 0.071100 0.039475 -0.031625 0.9928472467 0.0009736898 FALSE TRUE
MSTRG.17137.11 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding   21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.7657252 2.5954742 0.0000000 1.7272494 0.0000000 -8.025402 0.09900000 0.103700 0.000000 -0.103700 0.9928472467 0.0009736898 FALSE TRUE
MSTRG.17137.12 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding   21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 2.2785616 3.5426707 2.5767380 2.1074178 1.6652492 -0.457770 0.12131667 0.126600 0.179575 0.052975 1.0000000000 0.0009736898 FALSE TRUE
MSTRG.17137.14 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding   21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.7895625 0.9505436 2.7210017 0.9505436 1.9826053 1.507507 0.11699167 0.040875 0.180900 0.140025 0.9928472467 0.0009736898 FALSE TRUE
MSTRG.17137.15 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding   21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.6084692 3.8201550 1.0052527 1.6872199 1.0052527 -1.915564 0.06803333 0.150925 0.053175 -0.097750 0.9300585459 0.0009736898 FALSE TRUE
MSTRG.17137.16 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding   21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 2.9385721 0.0000000 8.8157162 0.0000000 8.8157162 9.785570 0.06292500 0.000000 0.188775 0.188775 0.9928472467 0.0009736898   FALSE
MSTRG.17137.21 ENSG00000144283 No_inf pgwt_inf PKP4 protein_coding   21.30775 26.0847 22.64592 1.484178 8.188276 -0.2038692 1.3953332 2.5553777 0.8586028 0.5950109 0.5006031 -1.562403 0.06325833 0.096400 0.041550 -0.054850 0.9589706568 0.0009736898 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000144283 E001 0.0000000       2 158456952 158456963 12 +      
ENSG00000144283 E002 0.0000000       2 158456964 158457098 135 +      
ENSG00000144283 E003 0.0000000       2 158457099 158457113 15 +      
ENSG00000144283 E004 0.4906449 0.0162375873 5.584203e-01   2 158457114 158457132 19 + 0.219 0.135 -0.839
ENSG00000144283 E005 0.6044509 0.0179511466 2.733080e-01   2 158457133 158457135 3 + 0.297 0.135 -1.424
ENSG00000144283 E006 1.3575348 0.1717599124 5.585020e-01 8.154190e-01 2 158457136 158457218 83 + 0.421 0.322 -0.576
ENSG00000144283 E007 0.6392859 0.0151564405 4.645848e-01   2 158457455 158457867 413 + 0.123 0.239 1.161
ENSG00000144283 E008 0.8668898 0.0743942100 7.076302e-01 8.910472e-01 2 158457868 158458192 325 + 0.297 0.239 -0.424
ENSG00000144283 E009 0.9024547 0.0248972846 2.183535e-01 5.414180e-01 2 158458193 158458307 115 + 0.123 0.322 1.746
ENSG00000144283 E010 0.0000000       2 158458308 158458331 24 +      
ENSG00000144283 E011 1.2794374 0.0358073238 2.980667e-01 6.256408e-01 2 158533180 158533184 5 + 0.219 0.392 1.161
ENSG00000144283 E012 1.2794374 0.0358073238 2.980667e-01 6.256408e-01 2 158533185 158533187 3 + 0.219 0.392 1.161
ENSG00000144283 E013 3.3399710 0.0043580412 3.520678e-01 6.722008e-01 2 158533188 158533316 129 + 0.693 0.574 -0.517
ENSG00000144283 E014 0.0000000       2 158533438 158533467 30 +      
ENSG00000144283 E015 0.1308632 0.0122240747 1.000000e+00   2 158533468 158533534 67 + 0.000 0.073 10.697
ENSG00000144283 E016 2.1898218 0.2716342212 2.136951e-01 5.357616e-01 2 158577271 158577302 32 + 0.631 0.392 -1.162
ENSG00000144283 E017 3.4016737 0.0043065063 2.219055e-02 1.538874e-01 2 158577303 158577340 38 + 0.795 0.505 -1.254
ENSG00000144283 E018 4.4189450 0.0033748730 8.147930e-02 3.264953e-01 2 158577341 158577383 43 + 0.839 0.633 -0.839
ENSG00000144283 E019 0.0000000       2 158578169 158578263 95 +      
ENSG00000144283 E020 0.1141751 0.0112204795 2.868858e-01   2 158588225 158588285 61 + 0.123 0.000 -12.605
ENSG00000144283 E021 0.2456901 0.0161690197 6.451214e-01   2 158588888 158588950 63 + 0.123 0.073 -0.839
ENSG00000144283 E022 3.6814741 0.0046599404 1.125769e-01 3.880184e-01 2 158603070 158603104 35 + 0.772 0.574 -0.839
ENSG00000144283 E023 0.1138060 0.0111247147 2.869542e-01   2 158606247 158606278 32 + 0.123 0.000 -12.605
ENSG00000144283 E024 4.7758943 0.0030508156 4.834114e-02 2.425785e-01 2 158620990 158621044 55 + 0.878 0.651 -0.913
ENSG00000144283 E025 6.7266342 0.0022288512 6.226231e-01 8.487859e-01 2 158621045 158621115 71 + 0.896 0.848 -0.187
ENSG00000144283 E026 2.8634967 0.0052365634 7.309164e-01 9.018521e-01 2 158621116 158621121 6 + 0.596 0.552 -0.202
ENSG00000144283 E027 18.9597156 0.0007399159 5.161264e-01 7.904680e-01 2 158621231 158621421 191 + 1.301 1.260 -0.143
ENSG00000144283 E028 9.9928087 0.0014734952 7.302115e-01 9.016796e-01 2 158624878 158624954 77 + 1.034 1.007 -0.102
ENSG00000144283 E029 14.4104359 0.0011849291 2.019893e-01 5.210556e-01 2 158624955 158625124 170 + 1.223 1.129 -0.337
ENSG00000144283 E030 17.8409985 0.0027793189 7.326016e-02 3.072781e-01 2 158625125 158625427 303 + 1.328 1.204 -0.436
ENSG00000144283 E031 14.8595011 0.0009543587 8.210016e-02 3.275759e-01 2 158631753 158631941 189 + 1.256 1.129 -0.452
ENSG00000144283 E032 0.0000000       2 158632474 158632642 169 +      
ENSG00000144283 E033 3.3369434 0.0629386314 4.249660e-01 7.296337e-01 2 158634070 158634072 3 + 0.693 0.574 -0.517
ENSG00000144283 E034 17.3248394 0.0008171994 4.302646e-01 7.334241e-01 2 158634073 158634289 217 + 1.271 1.219 -0.185
ENSG00000144283 E035 12.1753690 0.0011335382 9.017526e-03 8.670611e-02 2 158640627 158640759 133 + 1.223 1.014 -0.752
ENSG00000144283 E036 7.9406898 0.0114177429 3.149425e-01 6.409199e-01 2 158642486 158642519 34 + 0.993 0.891 -0.385
ENSG00000144283 E037 22.6903758 0.0006438585 4.978240e-02 2.469397e-01 2 158642520 158642699 180 + 1.424 1.306 -0.410
ENSG00000144283 E038 16.4195360 0.0030117889 1.877389e-02 1.387679e-01 2 158658131 158658314 184 + 1.322 1.152 -0.600
ENSG00000144283 E039 0.0000000       2 158661333 158661450 118 +      
ENSG00000144283 E040 0.2626639 0.0160692832 5.236224e-01   2 158661451 158661764 314 + 0.000 0.135 11.640
ENSG00000144283 E041 4.2002796 0.0035747605 2.781987e-07 1.768677e-05 2 158662242 158662896 655 + 0.000 0.836 15.134
ENSG00000144283 E042 10.6671153 0.0014609903 7.706953e-01 9.197144e-01 2 158662897 158662989 93 + 1.021 1.051 0.110
ENSG00000144283 E043 12.3383587 0.0123756382 4.411102e-01 7.413674e-01 2 158662990 158663057 68 + 1.047 1.123 0.272
ENSG00000144283 E044 9.3202915 0.0461953325 5.063117e-01 7.845090e-01 2 158663058 158663088 31 + 0.931 1.014 0.309
ENSG00000144283 E045 21.8745561 0.0006712343 1.455420e-01 4.411971e-01 2 158663272 158663445 174 + 1.391 1.302 -0.309
ENSG00000144283 E046 21.3454792 0.0013231741 5.691671e-01 8.206977e-01 2 158666413 158666563 151 + 1.294 1.336 0.148
ENSG00000144283 E047 0.3597871 0.0165001784 2.821860e-01   2 158666564 158666659 96 + 0.219 0.073 -1.839
ENSG00000144283 E048 1.8044802 0.0077995887 7.543401e-02 3.123627e-01 2 158669151 158669169 19 + 0.219 0.505 1.746
ENSG00000144283 E049 2.4089902 0.0060819600 3.898646e-01 7.034789e-01 2 158669170 158669302 133 + 0.421 0.552 0.646
ENSG00000144283 E050 5.5591751 0.0025986827 3.608397e-04 8.161711e-03 2 158669303 158669719 417 + 0.421 0.901 2.087
ENSG00000144283 E051 32.5066128 0.0005137883 7.584490e-01 9.142722e-01 2 158669720 158669915 196 + 1.507 1.494 -0.043
ENSG00000144283 E052 27.8261342 0.0005361828 8.863554e-02 3.416571e-01 2 158673677 158673761 85 + 1.493 1.401 -0.319
ENSG00000144283 E053 39.5967013 0.0004045615 2.634957e-01 5.916309e-01 2 158673883 158674000 118 + 1.541 1.600 0.202
ENSG00000144283 E054 12.3184961 0.0015120588 5.377462e-01 8.035500e-01 2 158676739 158676867 129 + 1.060 1.117 0.205
ENSG00000144283 E055 0.9010903 0.0132997179 2.145293e-01 5.366618e-01 2 158676868 158677355 488 + 0.123 0.322 1.746
ENSG00000144283 E056 30.7235493 0.0005454171 1.531412e-02 1.219753e-01 2 158678581 158678654 74 + 1.373 1.517 0.495
ENSG00000144283 E057 163.9751996 0.0001709017 1.042005e-05 4.411154e-04 2 158680429 158682879 2451 + 2.118 2.221 0.343

Help

Please Click HERE to learn more details about the results from DEXseq.