ENSG00000144354

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000347703 ENSG00000144354 No_inf pgwt_inf CDCA7 protein_coding protein_coding 6.254327 6.581523 6.499679 0.354539 0.2146738 -0.01802551 2.0899398 1.1065736 2.1997820 0.6450381 1.38591706 0.9848257 0.35145000 0.154000 0.341900 0.187900 1.0000000000 0.0001447298 FALSE TRUE
ENST00000410019 ENSG00000144354 No_inf pgwt_inf CDCA7 protein_coding protein_coding 6.254327 6.581523 6.499679 0.354539 0.2146738 -0.01802551 0.9363377 0.8663231 1.3224927 0.5087127 1.32249271 0.6045929 0.15330000 0.144475 0.217975 0.073500 0.9928472467 0.0001447298 FALSE TRUE
ENST00000496441 ENSG00000144354 No_inf pgwt_inf CDCA7 protein_coding retained_intron 6.254327 6.581523 6.499679 0.354539 0.2146738 -0.01802551 0.7448291 1.3934065 0.4278598 0.1477483 0.09343691 -1.6803921 0.11571667 0.213450 0.066075 -0.147375 0.7250300184 0.0001447298 FALSE TRUE
ENST00000695911 ENSG00000144354 No_inf pgwt_inf CDCA7 protein_coding nonsense_mediated_decay 6.254327 6.581523 6.499679 0.354539 0.2146738 -0.01802551 0.2166921 0.0000000 0.6500764 0.0000000 0.65007643 6.0445612 0.03399167 0.000000 0.101975 0.101975 0.9928472467 0.0001447298 FALSE TRUE
ENST00000695914 ENSG00000144354 No_inf pgwt_inf CDCA7 protein_coding protein_coding 6.254327 6.581523 6.499679 0.354539 0.2146738 -0.01802551 0.6074633 0.1308464 1.6915436 0.1308464 1.69154356 3.5946492 0.08557500 0.018175 0.238550 0.220375 1.0000000000 0.0001447298 FALSE TRUE
ENST00000695918 ENSG00000144354 No_inf pgwt_inf CDCA7 protein_coding protein_coding_CDS_not_defined 6.254327 6.581523 6.499679 0.354539 0.2146738 -0.01802551 1.4366721 2.7775657 0.0000000 0.1017289 0.00000000 -8.1228620 0.22370000 0.427075 0.000000 -0.427075 0.0001447298 0.0001447298   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000144354 E001 0.2450383 0.016299901 0.953477659   2 173354820 173354839 20 + 0.092 0.099 0.122
ENSG00000144354 E002 0.3767001 0.016593355 0.538634174   2 173354840 173354852 13 + 0.092 0.179 1.122
ENSG00000144354 E003 0.8679241 0.015300927 0.640663228 0.85784352 2 173354853 173354871 19 + 0.232 0.306 0.537
ENSG00000144354 E004 1.0964692 0.013446798 0.822750781 0.93980295 2 173354872 173354887 16 + 0.337 0.306 -0.200
ENSG00000144354 E005 1.0964692 0.013446798 0.822750781 0.93980295 2 173354888 173354892 5 + 0.337 0.306 -0.200
ENSG00000144354 E006 2.0778306 0.012199394 0.926288662 0.97937332 2 173354893 173354963 71 + 0.493 0.483 -0.048
ENSG00000144354 E007 1.0955365 0.013028160 0.825713698 0.94116365 2 173354964 173354984 21 + 0.337 0.306 -0.200
ENSG00000144354 E008 0.1308632 0.012399697 0.497304551   2 173355460 173355515 56 + 0.000 0.099 11.010
ENSG00000144354 E009 0.0000000       2 173358507 173358711 205 +      
ENSG00000144354 E010 0.7356886 0.033560479 0.929685670 0.98037182 2 173358712 173358714 3 + 0.232 0.247 0.122
ENSG00000144354 E011 2.4212534 0.036247471 0.501771936 0.78194819 2 173358715 173358837 123 + 0.582 0.483 -0.464
ENSG00000144354 E012 0.1138060 0.011676684 0.582348550   2 173359255 173359342 88 + 0.092 0.000 -11.618
ENSG00000144354 E013 0.1141751 0.011297378 0.582619994   2 173359343 173359386 44 + 0.092 0.000 -11.618
ENSG00000144354 E014 0.1141751 0.011297378 0.582619994   2 173359387 173359491 105 + 0.092 0.000 -11.618
ENSG00000144354 E015 4.6101911 0.023767232 0.505183734 0.78380445 2 173363226 173363462 237 + 0.790 0.706 -0.338
ENSG00000144354 E016 2.3232201 0.006424091 0.947370831 0.98673583 2 173363818 173363895 78 + 0.525 0.518 -0.030
ENSG00000144354 E017 1.0523490 0.020481546 0.001725011 0.02720557 2 173363896 173363999 104 + 0.000 0.483 13.513
ENSG00000144354 E018 1.7360678 0.010059209 0.509459012 0.78615026 2 173364000 173364161 162 + 0.382 0.483 0.537
ENSG00000144354 E019 4.3092014 0.005812354 0.002587994 0.03663634 2 173364162 173364794 633 + 0.493 0.868 1.596
ENSG00000144354 E020 3.3849832 0.046749737 0.359669827 0.67927215 2 173364795 173364893 99 + 0.698 0.581 -0.506
ENSG00000144354 E021 3.2057621 0.110996710 0.056431831 0.26567402 2 173364894 173364939 46 + 0.756 0.445 -1.393
ENSG00000144354 E022 3.9744600 0.003938669 0.170927685 0.47900775 2 173364940 173364989 50 + 0.773 0.609 -0.686
ENSG00000144354 E023 0.1311489 0.012495667 0.497197959   2 173364990 173365061 72 + 0.000 0.099 11.010
ENSG00000144354 E024 10.0107038 0.001500279 0.739364411 0.90578110 2 173365452 173365592 141 + 1.054 1.030 -0.090
ENSG00000144354 E025 0.0000000       2 173365593 173366282 690 +      
ENSG00000144354 E026 8.3278093 0.001850544 0.947630797 0.98673583 2 173366283 173366432 150 + 0.964 0.974 0.037
ENSG00000144354 E027 8.1348902 0.001834175 0.415516893 0.72276443 2 173367150 173367286 137 + 0.918 0.997 0.297
ENSG00000144354 E028 46.6507372 0.007833993 0.892498697 0.96737623 2 173367634 173368997 1364 + 1.674 1.681 0.023

Help

Please Click HERE to learn more details about the results from DEXseq.