ENSG00000145349

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000513132 ENSG00000145349 No_inf pgwt_inf CAMK2D protein_coding protein_coding 18.05552 13.34243 21.80219 0.7545657 1.086374 0.7080331 3.566704 1.7852585 4.821921 1.0745600 0.5370183 1.4284053 0.18429167 0.124000 0.219700 0.095700 0.9928472467 0.0002196727 FALSE TRUE
ENST00000699380 ENSG00000145349 No_inf pgwt_inf CAMK2D protein_coding protein_coding 18.05552 13.34243 21.80219 0.7545657 1.086374 0.7080331 1.319424 0.9891646 1.676366 0.2232241 0.1923836 0.7551233 0.07293333 0.073975 0.078050 0.004075 1.0000000000 0.0002196727 FALSE TRUE
ENST00000699415 ENSG00000145349 No_inf pgwt_inf CAMK2D protein_coding protein_coding_CDS_not_defined 18.05552 13.34243 21.80219 0.7545657 1.086374 0.7080331 2.834758 1.7131415 2.848655 1.7131415 1.6451186 0.7302955 0.15771667 0.127550 0.140550 0.013000 0.9928472467 0.0002196727 FALSE TRUE
ENST00000706056 ENSG00000145349 No_inf pgwt_inf CAMK2D protein_coding protein_coding 18.05552 13.34243 21.80219 0.7545657 1.086374 0.7080331 2.608440 0.0000000 5.236049 0.0000000 0.6359062 9.0350874 0.12768333 0.000000 0.242425 0.242425 0.0002196727 0.0002196727 FALSE TRUE
MSTRG.22197.21 ENSG00000145349 No_inf pgwt_inf CAMK2D protein_coding   18.05552 13.34243 21.80219 0.7545657 1.086374 0.7080331 4.480338 5.6200199 3.241388 1.4308832 1.8735959 -0.7920842 0.26970000 0.423975 0.139750 -0.284225 0.9244808265 0.0002196727 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000145349 E001 0.0000000       4 113418054 113419361 1308 -      
ENSG00000145349 E002 0.0000000       4 113420331 113420483 153 -      
ENSG00000145349 E003 0.0000000       4 113451032 113451037 6 -      
ENSG00000145349 E004 0.1145948 0.0111929737 8.296443e-01   4 113451038 113451044 7 - 0.079 0.000 -8.814
ENSG00000145349 E005 0.4746476 0.4541686032 7.959382e-01   4 113451045 113451063 19 - 0.203 0.115 -0.981
ENSG00000145349 E006 0.6063095 0.0189072010 9.877961e-01   4 113451064 113451067 4 - 0.203 0.205 0.021
ENSG00000145349 E007 0.8354991 0.0324290452 5.566627e-01 8.146381e-01 4 113451068 113451078 11 - 0.299 0.205 -0.716
ENSG00000145349 E008 45.7469740 0.0005231265 5.576865e-08 4.158054e-06 4 113451079 113452438 1360 - 1.548 1.784 0.801
ENSG00000145349 E009 2.5321549 0.0404444352 8.812201e-01 9.624689e-01 4 113452439 113452441 3 - 0.554 0.534 -0.094
ENSG00000145349 E010 2.7602802 0.0270890586 6.443410e-01 8.595726e-01 4 113452442 113452450 9 - 0.600 0.534 -0.301
ENSG00000145349 E011 24.0524836 0.0006065871 3.501859e-01 6.707063e-01 4 113452451 113452700 250 - 1.370 1.426 0.195
ENSG00000145349 E012 22.1756611 0.0006736962 7.192444e-01 8.969505e-01 4 113452701 113452802 102 - 1.351 1.374 0.080
ENSG00000145349 E013 27.0711629 0.0005435466 4.492669e-01 7.473977e-01 4 113452803 113452960 158 - 1.425 1.468 0.149
ENSG00000145349 E014 108.2906329 0.0029855901 3.372967e-01 6.600705e-01 4 113452961 113453913 953 - 2.020 2.052 0.107
ENSG00000145349 E015 8.4186704 0.0136099560 5.366728e-01 8.030210e-01 4 113453914 113453948 35 - 0.997 0.932 -0.242
ENSG00000145349 E016 17.6947329 0.0007941087 7.283059e-01 9.008309e-01 4 113453949 113454104 156 - 1.257 1.282 0.087
ENSG00000145349 E017 39.0203212 0.0004192479 6.272642e-01 8.507519e-01 4 113454105 113454515 411 - 1.588 1.611 0.080
ENSG00000145349 E018 14.1269125 0.0040037910 2.815617e-01 6.092446e-01 4 113454516 113455725 1210 - 1.137 1.223 0.306
ENSG00000145349 E019 2.0780247 0.0064642405 5.428155e-01 8.068292e-01 4 113455726 113455754 29 - 0.445 0.534 0.436
ENSG00000145349 E020 3.1892325 0.0101893620 3.029626e-01 6.298838e-01 4 113455755 113455821 67 - 0.554 0.693 0.606
ENSG00000145349 E021 7.1825340 0.0020050733 4.978179e-01 7.790566e-01 4 113455822 113456608 787 - 0.878 0.947 0.262
ENSG00000145349 E022 3.7737256 0.0038817962 3.376686e-02 1.974913e-01 4 113456609 113457182 574 - 0.775 0.493 -1.231
ENSG00000145349 E023 0.3596403 0.0165375874 8.804137e-01   4 113457183 113457187 5 - 0.145 0.115 -0.394
ENSG00000145349 E024 1.2913372 0.0127127483 1.292738e-01 4.173333e-01 4 113457188 113457290 103 - 0.445 0.205 -1.564
ENSG00000145349 E025 2.6475599 0.0069828926 7.513576e-01 9.108200e-01 4 113457291 113457330 40 - 0.577 0.534 -0.201
ENSG00000145349 E026 2.4198037 0.0072235379 9.782809e-01 9.970105e-01 4 113457331 113457334 4 - 0.529 0.534 0.021
ENSG00000145349 E027 31.0186530 0.0008278652 6.647406e-01 8.696871e-01 4 113457335 113457563 229 - 1.491 1.515 0.082
ENSG00000145349 E028 14.7737434 0.0014941251 2.841903e-01 6.118557e-01 4 113460147 113460241 95 - 1.227 1.146 -0.290
ENSG00000145349 E029 11.8165804 0.0013704089 6.946458e-01 8.840083e-01 4 113465529 113465604 76 - 1.117 1.085 -0.115
ENSG00000145349 E030 8.6433703 0.0044190184 3.974262e-01 7.097482e-01 4 113500463 113500508 46 - 1.014 0.932 -0.305
ENSG00000145349 E031 4.5238117 0.0406354104 2.378651e-01 5.632699e-01 4 113500509 113500511 3 - 0.803 0.636 -0.689
ENSG00000145349 E032 0.0000000       4 113502936 113502977 42 -      
ENSG00000145349 E033 0.0000000       4 113504976 113505007 32 -      
ENSG00000145349 E034 0.0000000       4 113505008 113505035 28 -      
ENSG00000145349 E035 0.0000000       4 113505036 113505068 33 -      
ENSG00000145349 E036 0.2285450 0.0154150247 4.217946e-01   4 113507454 113508030 577 - 0.145 0.000 -12.343
ENSG00000145349 E037 0.0000000       4 113508031 113508235 205 -      
ENSG00000145349 E038 0.0000000       4 113508236 113508268 33 -      
ENSG00000145349 E039 1.5074749 0.0165695132 6.552865e-02 2.893333e-01 4 113508269 113509637 1369 - 0.254 0.534 1.606
ENSG00000145349 E040 6.6125267 0.0199807110 1.923180e-02 1.404580e-01 4 113509638 113509672 35 - 0.979 0.693 -1.120
ENSG00000145349 E041 1.9737891 0.0744321053 2.533554e-02 1.671591e-01 4 113509673 113509675 3 - 0.600 0.205 -2.301
ENSG00000145349 E042 10.8920178 0.0088704626 1.277725e-01 4.144778e-01 4 113511104 113513327 2224 - 1.006 1.146 0.509
ENSG00000145349 E043 8.4765472 0.0234097821 1.989788e-01 5.168371e-01 4 113513328 113513370 43 - 1.030 0.883 -0.549
ENSG00000145349 E044 12.4319943 0.0018641347 9.571828e-02 3.560578e-01 4 113513830 113513913 84 - 1.179 1.040 -0.499
ENSG00000145349 E045 15.9975065 0.0009133789 2.856370e-02 1.788712e-01 4 113515069 113515191 123 - 1.289 1.127 -0.576
ENSG00000145349 E046 11.5759344 0.0013286600 6.607154e-01 8.675638e-01 4 113517563 113517657 95 - 1.111 1.075 -0.131
ENSG00000145349 E047 0.0000000       4 113530959 113531076 118 -      
ENSG00000145349 E048 11.8473122 0.0012195087 1.302547e-01 4.186434e-01 4 113531216 113531299 84 - 1.155 1.028 -0.460
ENSG00000145349 E049 10.1284345 0.0091511106 6.548532e-02 2.892382e-01 4 113537341 113537443 103 - 1.111 0.932 -0.657
ENSG00000145349 E050 0.1139502 0.0111907382 8.295769e-01   4 113547644 113547716 73 - 0.079 0.000 -11.427
ENSG00000145349 E051 6.9607411 0.0595786509 5.535117e-01 8.128727e-01 4 113548657 113548729 73 - 0.931 0.848 -0.319
ENSG00000145349 E052 7.8841853 0.0057037757 7.649173e-01 9.166743e-01 4 113552031 113552096 66 - 0.932 0.962 0.113
ENSG00000145349 E053 7.0158820 0.0027064839 9.952449e-01 1.000000e+00 4 113609152 113609206 55 - 0.900 0.900 0.000
ENSG00000145349 E054 0.0000000       4 113616551 113616634 84 -      
ENSG00000145349 E055 7.7804263 0.0023092102 2.223211e-01 5.464711e-01 4 113661713 113661772 60 - 0.988 0.866 -0.461
ENSG00000145349 E056 0.3941868 0.0284810900 4.571333e-02   4 113677508 113677608 101 - 0.000 0.280 12.681
ENSG00000145349 E057 0.7358806 0.0145523338 6.132155e-01 8.441288e-01 4 113679403 113679496 94 - 0.203 0.280 0.606
ENSG00000145349 E058 1.3957235 0.3980018037 3.299749e-01 6.538130e-01 4 113754739 113755090 352 - 0.203 0.534 2.022
ENSG00000145349 E059 0.1315150 0.0122427545 3.490207e-01   4 113759115 113759319 205 - 0.000 0.115 11.264
ENSG00000145349 E060 11.8689086 0.0042203886 2.084888e-01 5.290805e-01 4 113759320 113759414 95 - 1.149 1.040 -0.394
ENSG00000145349 E061 22.5697762 0.0006261988 9.606240e-03 9.052459e-02 4 113761004 113761927 924 - 1.431 1.268 -0.570

Help

Please Click HERE to learn more details about the results from DEXseq.