ENSG00000145604

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000274254 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding protein_coding 9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 0.2217910 0.0000000 0.6653731 0.00000000 0.3102947 6.0776129 0.01680000 0.000000 0.050400 0.050400 0.7270589667 0.0001057844 FALSE TRUE
ENST00000274255 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding protein_coding 9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 1.7359465 0.3583783 2.1700561 0.35837833 1.2708046 2.5651051 0.21619167 0.046275 0.280600 0.234325 0.9928472467 0.0001057844 FALSE TRUE
ENST00000513263 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding nonsense_mediated_decay 9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 1.2710368 2.2320145 0.0000000 0.21183310 0.0000000 -7.8086518 0.17186667 0.294150 0.000000 -0.294150 0.0001057844 0.0001057844 TRUE TRUE
ENST00000620197 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding protein_coding 9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 0.3905972 0.6355523 0.5362393 0.36981107 0.5362393 -0.2410007 0.04445833 0.097050 0.036325 -0.060725 0.9928472467 0.0001057844 FALSE TRUE
ENST00000677861 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding retained_intron 9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 0.5148323 0.6467581 0.5520623 0.08679694 0.1467375 -0.2246321 0.05840000 0.084950 0.051350 -0.033600 0.9928472467 0.0001057844 FALSE TRUE
ENST00000678129 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding protein_coding_CDS_not_defined 9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 0.4639421 0.5799494 0.0000000 0.57994937 0.0000000 -5.8825193 0.04584167 0.074875 0.000000 -0.074875 0.9928472467 0.0001057844 FALSE FALSE
ENST00000679015 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding protein_coding 9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 2.5161033 2.3981696 4.2951846 1.12958359 1.7384436 0.8381381 0.23476667 0.299400 0.301325 0.001925 1.0000000000 0.0001057844 FALSE FALSE
MSTRG.22793.19 ENSG00000145604 No_inf pgwt_inf SKP2 protein_coding   9.576534 7.6132 11.93475 0.6975326 2.132287 0.6479086 1.4781586 0.0000000 3.0746175 0.00000000 1.1488202 8.2689478 0.10800833 0.000000 0.219075 0.219075 0.2518974674 0.0001057844 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000145604 E001 0.0000000       5 36151989 36152066 78 +      
ENSG00000145604 E002 0.0000000       5 36152067 36152069 3 +      
ENSG00000145604 E003 0.0000000       5 36152070 36152082 13 +      
ENSG00000145604 E004 0.0000000       5 36152083 36152083 1 +      
ENSG00000145604 E005 0.0000000       5 36152084 36152094 11 +      
ENSG00000145604 E006 0.1138060 0.0110839964 0.6944100127   5 36152095 36152102 8 + 0.084 0.000 -9.665
ENSG00000145604 E007 0.2449549 0.0162275446 0.8356579673   5 36152103 36152106 4 + 0.084 0.107 0.380
ENSG00000145604 E008 0.2449549 0.0162275446 0.8356579673   5 36152107 36152108 2 + 0.084 0.107 0.380
ENSG00000145604 E009 0.2449549 0.0162275446 0.8356579673   5 36152109 36152110 2 + 0.084 0.107 0.380
ENSG00000145604 E010 0.8496938 0.0146717811 0.9792281308 0.997323022 5 36152111 36152121 11 + 0.269 0.264 -0.035
ENSG00000145604 E011 0.8496938 0.0146717811 0.9792281308 0.997323022 5 36152122 36152127 6 + 0.269 0.264 -0.035
ENSG00000145604 E012 1.0950147 0.0144686007 0.9467382683 0.986580514 5 36152128 36152131 4 + 0.317 0.326 0.058
ENSG00000145604 E013 2.5012248 0.0068008884 0.1655417691 0.471330134 5 36152132 36152167 36 + 0.625 0.427 -0.942
ENSG00000145604 E014 2.5012248 0.0068008884 0.1655417691 0.471330134 5 36152168 36152176 9 + 0.625 0.427 -0.942
ENSG00000145604 E015 3.2210621 0.0048507579 0.1419053418 0.435701011 5 36152177 36152224 48 + 0.706 0.510 -0.868
ENSG00000145604 E016 2.1405814 0.0119681714 0.1748204118 0.484850132 5 36152225 36152270 46 + 0.579 0.380 -0.998
ENSG00000145604 E017 0.1316618 0.0124485335 0.4134931234   5 36152271 36152770 500 + 0.000 0.107 11.491
ENSG00000145604 E018 1.3219979 0.0931341313 0.6647815099 0.869697025 5 36152771 36152807 37 + 0.398 0.326 -0.427
ENSG00000145604 E019 4.9344325 0.0043462980 0.3765564381 0.694092885 5 36152808 36152930 123 + 0.818 0.715 -0.413
ENSG00000145604 E020 7.0933784 0.0024986444 0.2218992803 0.545999744 5 36152931 36153042 112 + 0.962 0.837 -0.475
ENSG00000145604 E021 0.0000000       5 36159773 36159874 102 +      
ENSG00000145604 E022 0.0000000       5 36163372 36163644 273 +      
ENSG00000145604 E023 6.9950928 0.0031404225 0.4015989858 0.712646706 5 36163645 36163756 112 + 0.941 0.854 -0.330
ENSG00000145604 E024 0.6209975 0.0167631277 0.4627323242   5 36163757 36164534 778 + 0.155 0.264 0.965
ENSG00000145604 E025 0.1315150 0.0122775574 0.4137509419   5 36164535 36164627 93 + 0.000 0.107 11.492
ENSG00000145604 E026 0.0000000       5 36164628 36164695 68 +      
ENSG00000145604 E027 1.1284139 0.0142678311 0.1677508556 0.474326186 5 36164696 36166518 1823 + 0.216 0.427 1.380
ENSG00000145604 E028 3.8581970 0.0036315609 0.4950478327 0.776959512 5 36166519 36166555 37 + 0.724 0.639 -0.357
ENSG00000145604 E029 6.4918420 0.0234289945 0.2511022820 0.578133137 5 36166556 36166662 107 + 0.930 0.800 -0.501
ENSG00000145604 E030 7.3711059 0.0061463920 0.5152097500 0.789796786 5 36168313 36168447 135 + 0.951 0.887 -0.244
ENSG00000145604 E031 5.2505751 0.0030816683 0.6860030008 0.880333143 5 36170344 36170442 99 + 0.773 0.819 0.178
ENSG00000145604 E032 0.0000000       5 36170443 36170453 11 +      
ENSG00000145604 E033 6.3266028 0.0154604206 0.0612440314 0.278586538 5 36171603 36171733 131 + 0.951 0.738 -0.829
ENSG00000145604 E034 1.1577311 0.0108236300 0.0215355053 0.150921908 5 36171734 36174778 3045 + 0.467 0.107 -2.790
ENSG00000145604 E035 0.0000000       5 36174779 36174848 70 +      
ENSG00000145604 E036 0.0000000       5 36174849 36174877 29 +      
ENSG00000145604 E037 4.5257152 0.0031821508 0.0657002666 0.289722639 5 36176965 36177016 52 + 0.832 0.610 -0.915
ENSG00000145604 E038 5.6276636 0.0932946617 0.6578414021 0.866410456 5 36177185 36177292 108 + 0.789 0.854 0.255
ENSG00000145604 E039 4.6612589 0.0034408564 0.4157604133 0.722764427 5 36177293 36178597 1305 + 0.706 0.800 0.380
ENSG00000145604 E040 0.9811564 0.0212852093 0.7152234285 0.894423226 5 36178598 36178810 213 + 0.269 0.326 0.380
ENSG00000145604 E041 12.4611255 0.0012143233 0.0003072276 0.007222979 5 36178811 36181817 3007 + 0.972 1.256 1.025
ENSG00000145604 E042 72.9007085 0.0003015215 0.0074629201 0.076658557 5 36181818 36183839 2022 + 1.832 1.905 0.244
ENSG00000145604 E043 3.4966990 0.0051649503 0.5538757666 0.813126979 5 36183840 36184319 480 + 0.687 0.610 -0.330
ENSG00000145604 E044 0.0000000       5 36191412 36191522 111 +      
ENSG00000145604 E045 0.0000000       5 36191523 36191702 180 +      
ENSG00000145604 E046 0.0000000       5 36192621 36192695 75 +      
ENSG00000145604 E047 2.6306523 0.0057025827 0.2657510760 0.593885050 5 36194993 36196849 1857 + 0.625 0.471 -0.719

Help

Please Click HERE to learn more details about the results from DEXseq.