ENSG00000145723

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000399004 ENSG00000145723 No_inf pgwt_inf GIN1 protein_coding protein_coding 3.332452 3.610789 1.859398 0.5206519 0.2796944 -0.9537302 0.8805864 0.0000000 1.2973942 0.0000000 0.1223956 7.030550 0.37040833 0.000000 0.753800 0.753800 0.02608151 0.02608151 FALSE TRUE
ENST00000507478 ENSG00000145723 No_inf pgwt_inf GIN1 protein_coding protein_coding_CDS_not_defined 3.332452 3.610789 1.859398 0.5206519 0.2796944 -0.9537302 0.7495859 0.9398954 0.3447270 0.5669800 0.3447270 -1.421060 0.18437500 0.213425 0.131875 -0.081550 0.99284725 0.02608151   FALSE
ENST00000508629 ENSG00000145723 No_inf pgwt_inf GIN1 protein_coding protein_coding 3.332452 3.610789 1.859398 0.5206519 0.2796944 -0.9537302 0.6607722 0.7766843 0.2172768 0.4503493 0.2172768 -1.791334 0.21443333 0.285075 0.114325 -0.170750 0.99284725 0.02608151 FALSE TRUE
ENST00000512248 ENSG00000145723 No_inf pgwt_inf GIN1 protein_coding nonsense_mediated_decay 3.332452 3.610789 1.859398 0.5206519 0.2796944 -0.9537302 0.5868007 1.3539112 0.0000000 0.2053751 0.0000000 -7.091606 0.15049167 0.388425 0.000000 -0.388425 0.08927228 0.02608151 FALSE TRUE
ENST00000513747 ENSG00000145723 No_inf pgwt_inf GIN1 protein_coding nonsense_mediated_decay 3.332452 3.610789 1.859398 0.5206519 0.2796944 -0.9537302 0.1800992 0.5402977 0.0000000 0.5402977 0.0000000 -5.782140 0.03769167 0.113075 0.000000 -0.113075 1.00000000 0.02608151   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000145723 E001 6.3251823 0.004238116 0.004665549 0.05553869 5 103086000 103087812 1813 - 0.673 0.962 1.137
ENSG00000145723 E002 0.3607046 0.141592896 0.520853073   5 103087813 103087814 2 - 0.185 0.089 -1.225
ENSG00000145723 E003 4.4718175 0.018035712 0.578594789 0.82576078 5 103087815 103088125 311 - 0.696 0.760 0.260
ENSG00000145723 E004 2.6202654 0.005672930 0.435428412 0.73749150 5 103088126 103088172 47 - 0.494 0.596 0.475
ENSG00000145723 E005 7.3793681 0.002063465 0.737257045 0.90463264 5 103096541 103096826 286 - 0.938 0.904 -0.129
ENSG00000145723 E006 4.4788094 0.004304201 0.093662560 0.35191243 5 103097314 103097490 177 - 0.834 0.643 -0.778
ENSG00000145723 E007 3.1052694 0.005563904 0.015445248 0.12274348 5 103097590 103097781 192 - 0.761 0.449 -1.395
ENSG00000145723 E008 0.0000000       5 103102276 103102743 468 -      
ENSG00000145723 E009 2.7496099 0.006322908 0.333013372 0.65638243 5 103104541 103104699 159 - 0.494 0.620 0.582
ENSG00000145723 E010 2.4711431 0.027143398 0.882400582 0.96305751 5 103104700 103104846 147 - 0.529 0.543 0.064
ENSG00000145723 E011 0.0000000       5 103106564 103106715 152 -      
ENSG00000145723 E012 1.1582951 0.013008331 0.003408988 0.04442060 5 103106716 103106909 194 - 0.529 0.089 -3.395
ENSG00000145723 E013 1.3757651 0.010782950 0.498775733 0.77968223 5 103108569 103108714 146 - 0.314 0.412 0.582
ENSG00000145723 E014 0.7534610 0.015833496 0.514387252 0.78940669 5 103120064 103120138 75 - 0.185 0.280 0.775

Help

Please Click HERE to learn more details about the results from DEXseq.