ENSG00000146063

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000315073 ENSG00000146063 No_inf pgwt_inf TRIM41 protein_coding protein_coding 18.1644 19.90478 18.7842 0.4316702 0.3053239 -0.08355255 4.547207 3.725285 5.4982082 0.76436617 0.2098377 0.56036472 0.25709167 0.188750 0.293425 0.104675 9.928472e-01 2.242832e-05 FALSE TRUE
ENST00000515223 ENSG00000146063 No_inf pgwt_inf TRIM41 protein_coding retained_intron 18.1644 19.90478 18.7842 0.4316702 0.3053239 -0.08355255 1.785715 2.765467 1.6994701 0.09326739 0.1590754 -0.69918129 0.09590000 0.139075 0.090775 -0.048300 9.928472e-01 2.242832e-05 FALSE TRUE
MSTRG.24054.10 ENSG00000146063 No_inf pgwt_inf TRIM41 protein_coding   18.1644 19.90478 18.7842 0.4316702 0.3053239 -0.08355255 1.293191 2.718428 1.1611452 1.64799002 1.1611452 -1.22015003 0.06798333 0.142025 0.061925 -0.080100 9.928472e-01 2.242832e-05 FALSE TRUE
MSTRG.24054.11 ENSG00000146063 No_inf pgwt_inf TRIM41 protein_coding   18.1644 19.90478 18.7842 0.4316702 0.3053239 -0.08355255 3.871120 4.773173 4.6531778 2.11292393 1.6362310 -0.03665461 0.21251667 0.233675 0.246475 0.012800 1.000000e+00 2.242832e-05 TRUE TRUE
MSTRG.24054.14 ENSG00000146063 No_inf pgwt_inf TRIM41 protein_coding   18.1644 19.90478 18.7842 0.4316702 0.3053239 -0.08355255 2.164154 4.381004 0.8393446 0.70366524 0.4873706 -2.37012910 0.11129167 0.220650 0.044000 -0.176650 5.634549e-01 2.242832e-05 TRUE TRUE
MSTRG.24054.9 ENSG00000146063 No_inf pgwt_inf TRIM41 protein_coding   18.1644 19.90478 18.7842 0.4316702 0.3053239 -0.08355255 2.525397 0.000000 4.3270747 0.00000000 0.1889347 8.76057849 0.14895000 0.000000 0.230850 0.230850 2.242832e-05 2.242832e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000146063 E001 0.0000000       5 181222499 181222781 283 +      
ENSG00000146063 E002 0.0000000       5 181223281 181223289 9 +      
ENSG00000146063 E003 21.7515026 0.0006630438 0.0102818303 0.09447591 5 181223290 181224057 768 + 1.435 1.277 -0.550
ENSG00000146063 E004 6.8354788 0.0024439937 0.3728449202 0.69078075 5 181224058 181224165 108 + 0.941 0.848 -0.351
ENSG00000146063 E005 0.9827115 0.0850517185 0.8962259016 0.96874589 5 181224166 181224215 50 + 0.307 0.286 -0.144
ENSG00000146063 E006 3.0429029 0.0048857536 0.4035049560 0.71392028 5 181224216 181224315 100 + 0.663 0.552 -0.492
ENSG00000146063 E007 18.3685007 0.0060126740 0.0017091303 0.02701932 5 181224316 181224690 375 + 1.397 1.169 -0.801
ENSG00000146063 E008 0.0000000       5 181224691 181224812 122 +      
ENSG00000146063 E009 3.8192818 0.0237596321 0.0109649030 0.09872504 5 181224813 181230595 5783 + 0.447 0.803 1.572
ENSG00000146063 E010 0.3596939 0.0168255572 0.5249478752   5 181230596 181230743 148 + 0.180 0.091 -1.144
ENSG00000146063 E011 9.5487089 0.0041064790 0.0217609508 0.15166100 5 181230744 181230839 96 + 1.126 0.915 -0.775
ENSG00000146063 E012 20.5498413 0.0010259908 0.0008017018 0.01514560 5 181230840 181232658 1819 + 1.195 1.414 0.764
ENSG00000146063 E013 30.7872427 0.0006765938 0.3936919795 0.70687632 5 181232659 181232889 231 + 1.524 1.479 -0.156
ENSG00000146063 E014 15.9653023 0.0009096755 0.0327046227 0.19359474 5 181232890 181233408 519 + 1.134 1.288 0.545
ENSG00000146063 E015 2.3899775 0.0078169020 0.1631199383 0.46744319 5 181233409 181233412 4 + 0.406 0.605 0.971
ENSG00000146063 E016 9.8984208 0.0022156806 0.4958202527 0.77769633 5 181233413 181233435 23 + 1.000 1.060 0.218
ENSG00000146063 E017 9.0734786 0.0026255341 0.0036365745 0.04653205 5 181233436 181233635 200 + 0.824 1.102 1.040
ENSG00000146063 E018 11.8707455 0.0369321005 0.5137956978 0.78913658 5 181233636 181233705 70 + 1.142 1.077 -0.234
ENSG00000146063 E019 10.2543475 0.0015784934 0.2716414420 0.59977364 5 181233706 181233763 58 + 1.100 1.004 -0.351
ENSG00000146063 E020 3.7484996 0.0044227898 0.2330444468 0.55854829 5 181233764 181234124 361 + 0.583 0.734 0.644
ENSG00000146063 E021 1.3574819 0.0106776341 0.8884165093 0.96541552 5 181234125 181234173 49 + 0.359 0.380 0.119
ENSG00000146063 E022 16.5619577 0.0009274409 0.5130086304 0.78853335 5 181234174 181234349 176 + 1.216 1.261 0.158
ENSG00000146063 E023 41.1715584 0.0036642294 0.0546569736 0.26135112 5 181234350 181234931 582 + 1.673 1.577 -0.324
ENSG00000146063 E024 14.9074474 0.0009605189 0.9178038343 0.97593411 5 181234932 181234995 64 + 1.195 1.202 0.023
ENSG00000146063 E025 9.9208121 0.0021555993 0.3660469592 0.68487537 5 181234996 181235079 84 + 0.989 1.069 0.292
ENSG00000146063 E026 29.5652947 0.0161423980 0.4608820956 0.75482715 5 181235080 181235353 274 + 1.451 1.505 0.183
ENSG00000146063 E027 64.9490946 0.0002475351 0.3295562934 0.65347473 5 181235354 181235808 455 + 1.798 1.830 0.109

Help

Please Click HERE to learn more details about the results from DEXseq.