ENSG00000146067

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000506879 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding retained_intron 22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.6290236 4.1024540 0.0000000 0.6699762 0.0000000 -8.6838557 0.05860000 0.107900 0.000000 -0.107900 0.003765132 0.003765132   FALSE
ENST00000510163 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding nonsense_mediated_decay 22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 0.6025257 0.5039123 0.3400583 0.5039123 0.3400583 -0.5539272 0.05308333 0.012050 0.012150 0.000100 0.998351147 0.003765132 FALSE TRUE
ENST00000510479 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding nonsense_mediated_decay 22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.9162220 3.4816472 1.5624413 0.7094257 0.7300199 -1.1509016 0.08480833 0.094000 0.109150 0.015150 1.000000000 0.003765132 FALSE TRUE
ENST00000513502 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding retained_intron 22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.7528216 3.6014569 1.3029638 0.7099931 0.4762802 -1.4597538 0.06085000 0.094800 0.062600 -0.032200 0.992847247 0.003765132 FALSE FALSE
ENST00000515394 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding retained_intron 22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.3381325 1.4417456 2.5726518 0.9377137 0.9069346 0.8310645 0.05461667 0.039800 0.124050 0.084250 0.992847247 0.003765132 FALSE TRUE
ENST00000524677 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding protein_coding 22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.5691535 0.0000000 3.3374104 0.0000000 1.1164549 8.3869016 0.13203333 0.000000 0.199275 0.199275 0.138127143 0.003765132 FALSE TRUE
MSTRG.23992.1 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding   22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 0.6771407 0.0000000 1.2494804 0.0000000 0.7402318 6.9766849 0.05236667 0.000000 0.071200 0.071200 0.870331212 0.003765132 FALSE TRUE
MSTRG.23992.11 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding   22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.5849885 3.0284014 0.7879700 1.8197805 0.4914899 -1.9289061 0.06398333 0.076450 0.043425 -0.033025 1.000000000 0.003765132 FALSE TRUE
MSTRG.23992.13 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding   22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.7802880 3.2511697 0.9079269 0.5346451 0.6393403 -1.8289383 0.06901667 0.086925 0.036175 -0.050750 0.973714513 0.003765132   FALSE
MSTRG.23992.2 ENSG00000146067 No_inf pgwt_inf FAM193B protein_coding   22.19848 37.81617 18.85617 1.410553 3.422114 -1.003583 1.9744789 3.9186427 1.2538848 1.4317438 0.7279712 -1.6361660 0.07710833 0.100850 0.073625 -0.027225 0.992847247 0.003765132 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000146067 E001 0.3420755 0.0355510274 0.028555823   5 177519789 177519789 1 - 0.303 0.000 -10.899
ENSG00000146067 E002 0.4735905 0.0341478071 0.106590334   5 177519790 177519790 1 - 0.303 0.071 -2.506
ENSG00000146067 E003 0.4735905 0.0341478071 0.106590334   5 177519791 177519791 1 - 0.303 0.071 -2.506
ENSG00000146067 E004 9.0864018 0.0015232316 0.359373605 0.67917392 5 177519792 177519930 139 - 1.032 0.946 -0.320
ENSG00000146067 E005 11.8097432 0.0056295476 0.760845822 0.91500751 5 177519931 177520055 125 - 1.059 1.087 0.102
ENSG00000146067 E006 15.1485883 0.0033387380 0.821509100 0.93919363 5 177520056 177520181 126 - 1.190 1.172 -0.062
ENSG00000146067 E007 18.0198049 0.0008346456 0.694837947 0.88403037 5 177521974 177522071 98 - 1.268 1.240 -0.098
ENSG00000146067 E008 1.2943924 0.0111660247 0.075481479 0.31241907 5 177522072 177522162 91 - 0.126 0.415 2.249
ENSG00000146067 E009 1.9173322 0.0341324150 0.239927222 0.56570942 5 177522955 177523015 61 - 0.303 0.496 1.079
ENSG00000146067 E010 1.1667890 0.0852536187 0.138430248 0.43076279 5 177523159 177523162 4 - 0.126 0.384 2.079
ENSG00000146067 E011 1.2811110 0.0725963316 0.352872583 0.67297083 5 177523163 177523179 17 - 0.224 0.384 1.079
ENSG00000146067 E012 2.6906240 0.0071089736 0.120427573 0.40164718 5 177523180 177523265 86 - 0.371 0.605 1.166
ENSG00000146067 E013 2.0492351 0.0072667176 0.165763577 0.47170867 5 177523266 177523306 41 - 0.303 0.520 1.194
ENSG00000146067 E014 2.1635513 0.0202347944 0.340831367 0.66283379 5 177523307 177523374 68 - 0.371 0.520 0.779
ENSG00000146067 E015 16.6417687 0.0008697822 0.711449578 0.89274872 5 177523957 177524032 76 - 1.235 1.207 -0.097
ENSG00000146067 E016 71.7245733 0.0002466829 0.945084854 0.98613089 5 177524185 177525053 869 - 1.829 1.831 0.007
ENSG00000146067 E017 22.5555194 0.0005948079 0.267379716 0.59564077 5 177525054 177525196 143 - 1.291 1.363 0.251
ENSG00000146067 E018 7.1123548 0.0096496909 0.138131558 0.43041636 5 177525197 177525205 9 - 0.757 0.928 0.663
ENSG00000146067 E019 1.6740599 0.0754019953 0.162547743 0.46660950 5 177525206 177525487 282 - 0.224 0.471 1.538
ENSG00000146067 E020 8.2392592 0.0177394110 0.190124282 0.50469735 5 177531282 177531337 56 - 0.828 0.979 0.576
ENSG00000146067 E021 15.3562926 0.0028545286 0.517609638 0.79117998 5 177531338 177531521 184 - 1.217 1.167 -0.178
ENSG00000146067 E022 3.6509505 0.0165857206 0.696963832 0.88489725 5 177531522 177531834 313 - 0.606 0.659 0.231
ENSG00000146067 E023 6.4577737 0.0023767819 0.278658025 0.60675303 5 177531953 177532131 179 - 0.757 0.880 0.481
ENSG00000146067 E024 1.1322969 0.1808745365 0.894359997 0.96820757 5 177532132 177532155 24 - 0.303 0.315 0.078
ENSG00000146067 E025 1.8055646 0.0094618906 0.089601498 0.34365907 5 177532156 177532200 45 - 0.224 0.496 1.664
ENSG00000146067 E026 15.2151535 0.0126591583 0.647020778 0.86099679 5 177532443 177532641 199 - 1.150 1.193 0.151
ENSG00000146067 E027 0.3772050 0.1970658547 1.000000000   5 177536304 177536357 54 - 0.126 0.132 0.079
ENSG00000146067 E028 10.6328451 0.0106603093 0.722021564 0.89780841 5 177536358 177536432 75 - 1.059 1.026 -0.121
ENSG00000146067 E029 11.0853445 0.0012540887 0.349331310 0.67000817 5 177536433 177536486 54 - 1.107 1.026 -0.296
ENSG00000146067 E030 21.7799096 0.0018896975 0.012657635 0.10820169 5 177536487 177536745 259 - 1.430 1.270 -0.559
ENSG00000146067 E031 12.8045537 0.0012286512 0.790880894 0.92774823 5 177537873 177537986 114 - 1.095 1.117 0.079
ENSG00000146067 E032 5.7541243 0.0024598785 0.032322955 0.19237481 5 177537987 177538005 19 - 0.606 0.869 1.079
ENSG00000146067 E033 12.5606262 0.0011591564 0.738930786 0.90557702 5 177538006 177538084 79 - 1.083 1.111 0.100
ENSG00000146067 E034 9.1176291 0.0038884563 0.673482811 0.87377338 5 177538085 177538107 23 - 1.004 0.963 -0.153
ENSG00000146067 E035 7.5476557 0.0023704155 0.635156735 0.85456585 5 177538905 177538910 6 - 0.869 0.919 0.188
ENSG00000146067 E036 15.2743269 0.0012936196 0.876325613 0.96085618 5 177538911 177539042 132 - 1.190 1.178 -0.044
ENSG00000146067 E037 8.3316788 0.0113846457 0.357935661 0.67790612 5 177539043 177539147 105 - 1.004 0.909 -0.354
ENSG00000146067 E038 1.7516666 0.0092464955 0.929770894 0.98037182 5 177539148 177539351 204 - 0.429 0.415 -0.073
ENSG00000146067 E039 3.2234373 0.0140892893 0.428454332 0.73228535 5 177547168 177547228 61 - 0.673 0.564 -0.474
ENSG00000146067 E040 0.3599157 0.0166506408 0.264266396   5 177552042 177552131 90 - 0.224 0.071 -1.921
ENSG00000146067 E041 11.4564104 0.0013244098 0.011405735 0.10115782 5 177553168 177553350 183 - 1.199 0.988 -0.766
ENSG00000146067 E042 7.3170963 0.0018979136 0.215996193 0.53867343 5 177553351 177553496 146 - 0.974 0.848 -0.478
ENSG00000146067 E043 13.1515372 0.0011473786 0.003264497 0.04315216 5 177553497 177553802 306 - 0.925 1.188 0.959
ENSG00000146067 E044 8.1437151 0.0104999076 0.890061698 0.96614744 5 177553803 177554248 446 - 0.942 0.928 -0.053
ENSG00000146067 E045 9.2828821 0.0015091806 0.091899488 0.34828607 5 177554249 177554586 338 - 1.083 0.928 -0.573

Help

Please Click HERE to learn more details about the results from DEXseq.