ENSG00000146872

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000346027 ENSG00000146872 No_inf pgwt_inf TLK2 protein_coding protein_coding 22.2604 23.11745 21.2072 1.387323 0.4303297 -0.1243721 3.6779051 1.7847562 5.739635 0.7485622 0.5855072 1.6796826 0.16886667 0.079350 0.27235 0.193000 7.925812e-01 6.805785e-05 FALSE TRUE
ENST00000581041 ENSG00000146872 No_inf pgwt_inf TLK2 protein_coding protein_coding 22.2604 23.11745 21.2072 1.387323 0.4303297 -0.1243721 10.2313047 8.9911855 10.320380 0.8637473 0.4643413 0.1987064 0.45938333 0.386625 0.48780 0.101175 9.928472e-01 6.805785e-05 FALSE TRUE
ENST00000682274 ENSG00000146872 No_inf pgwt_inf TLK2 protein_coding nonsense_mediated_decay 22.2604 23.11745 21.2072 1.387323 0.4303297 -0.1243721 0.6907748 0.9986251 0.000000 0.9986251 0.0000000 -6.6562462 0.03210833 0.050450 0.00000 -0.050450 9.928472e-01 6.805785e-05 FALSE TRUE
MSTRG.13091.2 ENSG00000146872 No_inf pgwt_inf TLK2 protein_coding   22.2604 23.11745 21.2072 1.387323 0.4303297 -0.1243721 2.0474958 4.5049016 0.000000 0.5820624 0.0000000 -8.8185507 0.09022500 0.193700 0.00000 -0.193700 6.805785e-05 6.805785e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000146872 E001 0.0000000       17 62458658 62458761 104 +      
ENSG00000146872 E002 0.0000000       17 62458762 62458765 4 +      
ENSG00000146872 E003 0.1308632 0.0123916217 0.590193731   17 62470917 62470932 16 + 0.000 0.090 10.067
ENSG00000146872 E004 0.1308632 0.0123916217 0.590193731   17 62470933 62470941 9 + 0.000 0.090 12.331
ENSG00000146872 E005 0.1308632 0.0123916217 0.590193731   17 62470942 62470958 17 + 0.000 0.090 12.331
ENSG00000146872 E006 0.1308632 0.0123916217 0.590193731   17 62470959 62471078 120 + 0.000 0.090 12.331
ENSG00000146872 E007 2.1288565 0.0131974825 0.315279999 0.64119033 17 62477496 62477697 202 + 0.407 0.550 0.714
ENSG00000146872 E008 2.0141862 0.0071451917 0.188091248 0.50244176 17 62477768 62477838 71 + 0.361 0.550 0.977
ENSG00000146872 E009 2.3749010 0.0066257932 0.349833087 0.67036925 17 62477839 62478065 227 + 0.449 0.577 0.617
ENSG00000146872 E010 0.3774055 0.0166911080 0.644178459   17 62478066 62478081 16 + 0.100 0.165 0.840
ENSG00000146872 E011 2.3335416 0.0412662757 0.001326286 0.02227372 17 62478825 62479024 200 + 0.732 0.229 -2.663
ENSG00000146872 E012 0.9299652 0.0119609894 0.018892675 0.13907368 17 62479025 62479129 105 + 0.449 0.090 -2.968
ENSG00000146872 E013 0.4731636 0.0235127891 0.278194457   17 62479130 62479149 20 + 0.250 0.090 -1.745
ENSG00000146872 E014 0.4731636 0.0235127891 0.278194457   17 62479150 62479168 19 + 0.250 0.090 -1.745
ENSG00000146872 E015 0.5869696 0.0154541231 0.142870205   17 62479169 62479178 10 + 0.309 0.090 -2.160
ENSG00000146872 E016 0.4561064 0.0160659813 0.035954547   17 62479179 62479183 5 + 0.309 0.000 -15.127
ENSG00000146872 E017 0.3419313 0.0157631134 0.085958267   17 62479184 62479205 22 + 0.250 0.000 -14.785
ENSG00000146872 E018 0.6837183 0.0244965705 0.007246418 0.07530997 17 62479206 62479245 40 + 0.407 0.000 -15.577
ENSG00000146872 E019 0.9129079 0.0123570309 0.001387628 0.02305874 17 62479246 62479257 12 + 0.487 0.000 -15.905
ENSG00000146872 E020 2.0435619 0.0143649970 0.166110476 0.47213788 17 62479258 62479290 33 + 0.585 0.378 -1.035
ENSG00000146872 E021 0.2622978 0.2278423577 0.327411852   17 62479302 62479443 142 + 0.000 0.165 13.004
ENSG00000146872 E022 0.1139502 0.0111726043 0.489780238   17 62479444 62479613 170 + 0.100 0.000 -13.392
ENSG00000146872 E023 1.4213989 0.0094321195 0.055569957 0.26348250 17 62481121 62481123 3 + 0.522 0.229 -1.745
ENSG00000146872 E024 1.5529139 0.0087482860 0.118655475 0.39861692 17 62481124 62481125 2 + 0.522 0.285 -1.330
ENSG00000146872 E025 1.9123293 0.0074231103 0.090607255 0.34550535 17 62481126 62481137 12 + 0.585 0.334 -1.298
ENSG00000146872 E026 3.8933254 0.0472042039 0.355743989 0.67569592 17 62481138 62481206 69 + 0.753 0.628 -0.523
ENSG00000146872 E027 0.0000000       17 62486004 62486097 94 +      
ENSG00000146872 E028 0.0000000       17 62507381 62507449 69 +      
ENSG00000146872 E029 0.9459354 0.0851232700 0.143708636 0.43851749 17 62508408 62508553 146 + 0.407 0.165 -1.745
ENSG00000146872 E030 5.7125629 0.0129013429 0.419537660 0.72584682 17 62520773 62520844 72 + 0.772 0.861 0.347
ENSG00000146872 E031 6.5854597 0.0094246229 0.394628111 0.70752425 17 62522204 62522273 70 + 0.826 0.913 0.334
ENSG00000146872 E032 5.3524569 0.0037204010 0.225377612 0.54958181 17 62523134 62523177 44 + 0.873 0.732 -0.556
ENSG00000146872 E033 4.3211292 0.0033244649 0.824957568 0.94078835 17 62524236 62524331 96 + 0.711 0.732 0.088
ENSG00000146872 E034 3.5239610 0.0042623067 0.100014982 0.36458147 17 62536170 62536337 168 + 0.522 0.732 0.918
ENSG00000146872 E035 0.1139502 0.0111726043 0.489780238   17 62552302 62552397 96 + 0.100 0.000 -13.392
ENSG00000146872 E036 0.1141751 0.0111998864 0.489743709   17 62552687 62552874 188 + 0.100 0.000 -13.392
ENSG00000146872 E037 0.1315150 0.0122027902 0.590612284   17 62553444 62553662 219 + 0.000 0.090 12.331
ENSG00000146872 E038 2.7663778 0.0109622409 0.142993609 0.43767059 17 62553663 62553755 93 + 0.449 0.651 0.939
ENSG00000146872 E039 4.2391360 0.0150847948 0.297336077 0.62506942 17 62560016 62560126 111 + 0.640 0.768 0.532
ENSG00000146872 E040 0.1311489 0.0122675573 0.590424732   17 62560127 62560309 183 + 0.000 0.090 12.331
ENSG00000146872 E041 0.0000000       17 62564760 62565000 241 +      
ENSG00000146872 E042 13.2912277 0.0011308092 0.909352128 0.97321143 17 62565001 62565137 137 + 1.160 1.145 -0.053
ENSG00000146872 E043 0.4909232 0.0159195362 0.924052202   17 62572847 62573214 368 + 0.181 0.165 -0.160
ENSG00000146872 E044 14.8990612 0.0010341081 0.204448791 0.52378594 17 62573215 62573367 153 + 1.251 1.152 -0.350
ENSG00000146872 E045 0.2458369 0.0162793147 0.940860071   17 62574345 62574410 66 + 0.100 0.090 -0.160
ENSG00000146872 E046 12.0191910 0.0088173550 0.664709080 0.86968705 17 62576709 62576775 67 + 1.136 1.092 -0.160
ENSG00000146872 E047 17.8238494 0.0009953311 0.347460428 0.66825898 17 62578477 62578574 98 + 1.238 1.296 0.202
ENSG00000146872 E048 1.8031661 0.0083081763 0.008829671 0.08551942 17 62578575 62580110 1536 + 0.181 0.577 2.425
ENSG00000146872 E049 8.4316482 0.0023681292 0.413969688 0.72152361 17 62580111 62580192 82 + 0.930 1.001 0.267
ENSG00000146872 E050 0.2633236 0.2711873862 0.336730780   17 62585596 62586134 539 + 0.000 0.165 12.970
ENSG00000146872 E051 4.4387512 0.0195246592 0.981968964 0.99840658 17 62586135 62586226 92 + 0.732 0.732 0.000
ENSG00000146872 E052 0.2454652 0.0161566923 0.940112114   17 62586227 62586413 187 + 0.100 0.090 -0.160
ENSG00000146872 E053 0.6220721 0.0149317876 0.734619021   17 62586414 62586466 53 + 0.181 0.229 0.425
ENSG00000146872 E054 0.1316618 0.0123573813 0.590318300   17 62586467 62586703 237 + 0.000 0.090 12.331
ENSG00000146872 E055 8.6087968 0.0034719915 0.871327753 0.95947486 17 62596585 62596674 90 + 0.991 0.970 -0.078
ENSG00000146872 E056 0.0000000       17 62597220 62597258 39 +      
ENSG00000146872 E057 2.2255849 0.0074135645 0.794048858 0.92907094 17 62597259 62599741 2483 + 0.487 0.521 0.162
ENSG00000146872 E058 0.3935270 0.0159650905 0.122630734   17 62600278 62600592 315 + 0.000 0.229 13.755
ENSG00000146872 E059 17.5104879 0.0008440050 0.311197705 0.63731535 17 62600651 62600820 170 + 1.304 1.230 -0.261
ENSG00000146872 E060 10.2917913 0.0111521709 0.537702623 0.80355004 17 62602042 62602180 139 + 1.084 1.021 -0.229
ENSG00000146872 E061 0.0000000       17 62606096 62606129 34 +      
ENSG00000146872 E062 0.0000000       17 62606130 62606241 112 +      
ENSG00000146872 E063 0.2446691 0.0163605738 0.941017028   17 62607387 62608040 654 + 0.100 0.090 -0.160
ENSG00000146872 E064 12.9268633 0.0012145264 0.998081936 1.00000000 17 62608041 62608148 108 + 1.144 1.138 -0.023
ENSG00000146872 E065 0.3604317 0.0165768019 0.526414509   17 62611946 62612391 446 + 0.181 0.090 -1.160
ENSG00000146872 E066 94.9606382 0.0002505741 0.048808400 0.24395469 17 62612392 62615481 3090 + 1.953 1.998 0.149

Help

Please Click HERE to learn more details about the results from DEXseq.